- ►diabetesjournals.org JC Henquin - Diabetes, 2004 - Am Diabetes Assoc Physiologically, insulin secretion is subject to a dual, hierarchal control by triggering and amplifying
pathways. By closing ATP-sensitive K + channels (K ATP channels) in the plasma
membrane, glucose and other metabolized nutrients depolarize β-cells, stimulate Ca 2+ ... Cited by 37 - Related articles - BL Direct - All 4 versions
- ►jbc.org M Nenquin, A Szollosi, L Aguilar-Bryan, J Bryan, JC … - Journal of Biological …, 2004 - ASBMB In normal -cells glucose induces insulin secretion by activating both a triggering pathway (closure
of K ATP channels, depolarization, and rise in cytosolic [Ca 2+ ] i ) and an amplifying pathway
(augmentation of Ca 2+ efficacy on exocytosis). It is unclear if and how nutrients can ... Cited by 44 - Related articles - BL Direct - All 5 versions
[CITATION] ves-Guerra MC, Goubern M, Surwit R, Bouillaud F, Richard D, Collins S, Ricquier D …
JC HENQUIN, B Brussels - MEDICOGRAPHIA, 2005 - medicographia.com The pathogenesis of type 2 diabetes is complex, involving defects in both insulin secretion and
action. Therefore, treatment of the disease is usually multifactorial, associating lifestyle changes
(exercise, diet) and pharmacological approaches aimed at decreasing hepatic glucose ... Related articles - View as HTML - All 2 versions
C Vanhoutte, A Sener, WJ Malaisse - Molecular and cellular biochemistry, 1997 - Springer It was recently proposed that stimulation of pancreatic islet by D-glucose results in the translocation
of glucokinase from the perinuclear area to the cell periphery, where the enzyme might conceivably
interact with either the glucose transporter GLUT- 2 or some other proteins and, by doing ... Cited by 6 - Related articles - BL Direct - All 5 versions
- ►physiology.org E Heart, RF Corkey, JD Wikstrom, OS … - American Journal of …, 2006 - Am Physiological Soc We examined the effects of different physiological concentrations of glucose on cytoplasmic Ca
2+ handling and mitochondrial membrane potential ( m ) and insulin secretion in single mouse
islet cells. The threshold for both glucose-induced changes in Ca 2+ and m ranged from 6 ... Cited by 24 - Related articles - BL Direct - All 5 versions
Y Takeda, MA Pérez-Pinzón, MD Ginsberg, TJ … - Journal of Cerebral Blood …, 2004 - nature.com The direction of the chemical reaction of ATP synthetase is reversible. The present study was
designed to determine whether mitochondria produce or consume ATP during ischemia. For
this purpose, changes in mitochondrial membrane potential were measured in vivo at the ... Cited by 9 - Related articles - BL Direct - All 7 versions
AV Kuznetsov, S Schneeberger, O Renz, H … - Transplantation, 2004 - journals.lww.com Background. Mitochondria play a critical role in ischemia-reperfusion injury of the heart. The
purpose of the present study was to analyze the intracellular region-specific functional state of
mitochondria after cold ischemia-reperfusion in a rat heart transplant model. Methods. ... Cited by 9 - Related articles - BL Direct - All 4 versions
J Bryan, WH Vila-Carriles, G Zhao, AP Babenko, L … - Diabetes, 2004 - Am Diabetes Assoc Advances in understanding the overall structural features of inward rectifiers and ATP-binding
cassette (ABC) transporters are providing novel insight into the architecture of ATP-sensitive
K + channels (K ATP channels) (K IR 6.0/SUR) 4 . The structure of the K IR pore has been ... Cited by 44 - Related articles - BL Direct - All 4 versions
JC Henquin, MA Ravier, M Nenquin, … - … Journal of Clinical …, 2003 - journals.indexcopernicus.com logo IndexCopernicus, Current language: English. IC Journals Master List. Journal of the Week.
Journals Master List. Journals from CC list. Recently Added Journals. Top 100 Journals.
Publishers. Top 20 Publishers. Journal Search. Evaluation methodology. ... Cited by 79 - Related articles - BL Direct - All 4 versions