A Farret, M Vignaud, S Dietz, J Vignon, P … - Diabetes, 2004 - Am Diabetes Assoc Purine nucleotides and their analogs increase insulin secretion through
activation of pancreatic β-cell P2Y receptors. The present study aimed at
determining the role of glucose metabolism in the response to P2Y agonists ... Cited by 12 - Related articles - BL Direct - All 5 versions
H Chevassus, A Roig, C Belloc, AD Lajoix, C … - Naunyn-Schmiedeberg's archives of pharmacology, 2002 - Springer Abstract Adenine nucleotides stimulate insulin secretion by binding to P2
receptors of the pancreatic β-cells; the stimulus-secretion coupling is not yet
clearly established and may depend on the receptor subtype. The aim of the ... Cited by 10 - Related articles - BL Direct - All 3 versions
A Farret, R Filhol, N Linck, M Manteghetti, J … - Pharmaceutical research, 2006 - Springer Received May 5, 2006; accepted July 5, 2006; published online October 18, 2006
Purpose. A series of C2-substituted ATP analogues was previously shown to have
potent insulin- secreting properties, yet with poor tissue-selectivity for ... Cited by 4 - Related articles - All 5 versions
L Lugo-Garcia, R Filhol, AD Lajoix, R Gross, P … - European journal of pharmacology, 2007 - Elsevier Purinergic P2Y-receptor agonists amplify glucose-induced insulin secretion from
pancreatic β-cells, thus offering new opportunities for the treatment of type 2
diabetes. However, little is known about which subtypes of purinergic P2Y ... Cited by 7 - Related articles - All 5 versions
J Fernandez-Alvarez, D Hillaire-Buys, MM … - Pancreas, 2001 - journals.lww.com Although P2 receptors for adenosine 5`-triphosphate (ATP) and/or adenosine
5`-diphosphate (ADP) have been characterized in mammalian pancreatic β cells,
no evidence for an insulin-secreting effect of P2 receptor agonists has ... Cited by 27 - Related articles - BL Direct - All 4 versions
C Léon, M Freund, O Latchoumanin, A Farret, … - Purinergic Signalling, 2005 - Springer & Christian Gachet 1 1 Institut National de la Santé et de la Recherche
Médicale U.311, Etablissement Français du Sang-Alsace, Strasbourg Cedex,
France; 2 Centre de Pharmacologie et Biotechnologie pour la Santé, CNRS ... Cited by 10 - Related articles - All 5 versions
- ►nrc-cnrc.gc.ca [PDF] EJ Verspohl, B Johannwille, A Waheed, H … - Canadian journal of physiology and pharmacology, 2002 - article.pubs.nrc-cnrc.gc.ca 5.6 and 8.3 mM glucose. This is compatible with the view that either two
different receptors are involved, or the cells desensitize and (or) the effect
of an inhibitory degradation product such as adenosine (ectonucleotidase ... Cited by 23 - Related articles - BL Direct - All 7 versions
- ►ucl.ac.uk [PDF] R Coutinho-Silva, M Parsons, T Robson, J … - Molecular and cellular endocrinology, 2003 - Elsevier The expression of the nucleotide receptors P2X 1 , P2X 2 , P2X 7 , P2Y 1 , P2Y 2
and P2Y 4 , in the pancreas of the streptozotocin-induced diabetic rat was
investigated using immunohistochemistry. In diabetic animals, P2X 7 ... Cited by 28 - Related articles - All 20 versions
P Petit, D Hillaire-Buys, MM Loubatieres- … - Handbook of experimental pharmacology, 2001 - cat.inist.fr Purinergic receptors and the pharmacology of type 2 diabetes. P PETIT,
D HILLAIRE-BUYS, MM LOUBATIERES-MARIANI, J CHAPAL Handbook ... Cited by 9 - Related articles - BL Direct
- ►physiology.org E Tuduri, E Filiputti, EM Carneiro, I Quesada - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Glucagon secreted from pancreatic -cells plays a critical role in glycemia,
mainly by hepatic glucose mobilization. In diabetic patients, an impaired
control of glucagon release can worsen glucose homeostasis. Despite its ... Cited by 2 - Related articles - BL Direct - All 3 versions
