AM Efanov, S Sewing, K Bokvist, J Gromada - Diabetes, 2004 - Am Diabetes Assoc Liver X receptors (LXRs) α and β, transcription factors of a nuclear hormone
receptor family, are expressed in pancreatic islets as well as
glucagon-secreting and insulin-secreting cell lines. Culture of pancreatic ... Cited by 60 - Related articles - BL Direct - All 5 versions
I Gerin, VW Dolinsky, JG Shackman, RT … - Journal of Biological Chemistry, 2005 - ASBMB Liver X receptors (LXR) α and β are nuclear oxysterol receptors with
established roles in cholesterol, lipid, and carbohydrate metabolism. Although
LXRs have been extensively studied in liver and macrophages, the importance ... Cited by 55 - Related articles - All 7 versions
G Cao, Y Liang, CL Broderick, BA Oldham, TP … - Journal of Biological Chemistry, 2003 - ASBMB The oxysterol receptors LXR (liver X receptor)-α and LXRβ are nuclear
receptors that play a key role in regulation of cholesterol and fatty acid
metabolism. We found that LXRs also play a significant role in glucose ... Cited by 160 - Related articles - BL Direct - All 4 versions
- ►endojournals.org W Wente, MB Brenner, H Zitzer, J Gromada, … - Endocrinology, 2007 - Endocrine Soc Liver X receptors (LXRs) form functional heterodimers with the retinoid X
receptors (RXRs) and regulate cholesterol, lipid, and glucose metabolism. We
demonstrated previously that activation of LXR modulates insulin secretion ... Cited by 22 - Related articles - BL Direct - All 3 versions
- ►endojournals.org H Zitzer, W Wente, MB Brenner, S Sewing, K … - Endocrinology, 2006 - Endocrine Soc Liver X receptors (LXR and LXRß) regulate glucose and lipid metabolism.
Pancreatic ß-cells and INS-1E insulinoma cells express only the LXRß isoform.
Activation of LXRß with the synthetic agonist T0901317 increased glucose- ... Cited by 23 - Related articles - BL Direct - All 4 versions
- ►physiology.org A Grefhorst, TH van Dijk, A Hammer, FH van … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Liver X receptor (LXR) agonists have been proposed to act as anti-diabetic
drugs. However, pharmacological LXR activation leads to severe hepatic
steatosis, a condition usually associated with insulin resistance and type ... Cited by 54 - Related articles - BL Direct - All 8 versions
BA Laffitte, LC Chao, J Li, R Walczak, S … - Proceedings of the National Academy of Sciences of …, 2003 - National Acad Sciences The control of lipid and glucose metabolism is closely linked. The nuclear
receptors liver X receptor (LXR)α and LXRβ have been implicated in gene
expression linked to lipid homeostasis; however, their role in glucose ... Cited by 227 - Related articles - BL Direct - All 10 versions
- ►diabetesjournals.org ET Kase, AJ Wensaas, V Aas, K Højlund, K … - Diabetes, 2005 - Am Diabetes Assoc Liver X receptors (LXRs) are important regulators of cholesterol and lipid
metabolism and are also involved in glucose metabolism. However, the functional
role of LXRs in human skeletal muscle is at present unknown. This study ... Cited by 37 - Related articles - All 6 versions
A Helleboid-Chapman, S Helleboid, H Jakel, C … - Cell Research, 2006 - nature.com Liver X receptors (LXRs) are members of the nuclear receptor superfamily, which
have been implicated in lipid homeostasis and more recently in glucose
metabolism. Here, we show that glucose does not change LXR protein level, ... Cited by 16 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org SS Choe, AH Choi, JW Lee, KH Kim, JJ Chung, … - Diabetes, 2007 - Am Diabetes Assoc Liver X receptor (LXR)α and LXRβ play important roles in fatty acid metabolism
and cholesterol homeostasis. Although the functional roles of LXR in the liver,
intestine, fat, and macrophages are well established, its role in ... Cited by 23 - Related articles - BL Direct - All 6 versions
