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Scholar Results 1 - 10 of about 101 related to Santini: Effect of PPAR-γ activation and inhibition on glucose-stimulated insulin release.... (0.13 sec) 

Effect of PPAR-γ activation and inhibition on glucose-stimulated insulin release in INS-1e …


E Santini, P Fallahi, SM Ferrari, A Masoni, A … - Diabetes, 2004 - Am Diabetes Assoc
Peroxisome proliferator-activated receptor (PPAR)-γ is expressed in human
β-cells and in the rat β-cell line INS-1. Previous studies have suggested that
PPAR-γ agonism (eg, thiazolidinediones) enhances glucose-stimulated ...
Cited by 11 - Related articles - BL Direct - All 4 versions

Insights into PPARγ from structures with endogenous and covalently bound ligands


KW Nettles - Nature Structural & Molecular Biology, 2008 - nature.com
Peroxisome proliferator–activated receptor- (PPAR ) is a ligand-regulated
transcription factor with crucial roles in carbohydrate and lipid metabolism and
adipogenesis, but the structural details of the binding and activation by ...
Cited by 2 - Related articles - All 2 versions

[PDF] The functions of PPARs in aging and longevity


A Erol - PPAR research, 2007 - hindawi.com
Page 1. Hindawi Publishing Corporation PPAR Research Volume 2007, Article
ID 39654, 10 pages doi:10.1155/2007/39654 Review Article ...
Cited by 3 - Related articles - View as HTML - All 11 versions

Inflammatory pathways are activated during cardiomyocyte hypertrophy and attenuated by …


PJH Smeets, BEJ Teunissen, A Planavila, H … - Journal of Biological Chemistry, 2008 - ASBMB
Accumulating evidence indicates an important role for inflammation in cardiac
hypertrophy and failure. Peroxisome proliferator-activated receptors (PPARs)
have been reported to attenuate inflammatory signaling pathways and, as ...
Cited by 4 - Related articles - All 3 versions

Induction of CXCR2 Receptor by Peroxisome Proliferator-Activated Receptor {gamma} in …

- ahajournals.org
E Rigamonti, C Fontaine, B Lefebvre, C Duhem … - Arteriosclerosis, Thrombosis, and Vascular Biology, 2008 - Am Heart Assoc
Objective— Macrophages play a central role in the immune response against
infectious organisms. Once activated, macrophages secrete proinflammatory
cytokines and chemokines. Interleukin (IL)-8 and related CXC chemokines ...
Cited by 3 - Related articles - All 5 versions

Nuclear receptor agonists improve insulin responsiveness in cultured cardiomyocytes …

- endojournals.org
C Montessuit, I Papageorgiou, R Lerch - Endocrinology, 2008 - Endocrine Soc
Insulin resistance is the failure of insulin to stimulate the transport of
glucose into its target cells. A highly regulatable supply of glucose is
important for cardiomyocytes to cope with situations of metabolic stress. ...
Cited by 4 - Related articles - BL Direct - All 3 versions

Bcr kinase activation by angiotensin II inhibits peroxisome proliferator-activated receptor { …


JD Alexis, N Wang, W Che, N Lerner- … - Circulation Research, 2009 - Am Heart Assoc
Bcr is a serine/threonine kinase activated by platelet-derived growth factor
that is highly expressed in the neointima after vascular injury. Here, we
demonstrate that Bcr is an important mediator of angiotensin (Ang) II and ...
Cited by 4 - Related articles - All 5 versions

PPARgamma and its ligands: therapeutic implications in cardiovascular disease.


L Villacorta, FJ Schopfer, J Zhang, BA … - Clinical science (London, England: 1979), 2009 - ncbi.nlm.nih.gov
The relevance of PPARgamma (peroxisome-proliferator-activated receptor gamma) as
an important therapeutic target for the treatment of diabetes arises from its
hypoglycaemic effects in diabetic patients and also from the critical role ...
Cited by 4 - Related articles - All 5 versions

Can Exercise Mimetics Substitute for Exercise?


EA Richter, B Kiens, JFP Wojtaszewski - Cell Metabolism, 2008 - Elsevier
Exercise training leads to multiple adaptations in the body. Well-documented
effects are within the cardiovascular and the musculoskeletal systems, but in
reality there are probably few, if any, organs that are not affected. These ...
Cited by 4 - Related articles - All 3 versions

Troglitazone ameliorates lipotoxicity in the beta cell line INS-1 expressing PPAR gamma


T Kawai, H Hirose, Y Seto, H Fujita, H Fujita, … - Diabetes research and clinical practice, 2002 - Elsevier
To elucidate the mechanisms by which troglitazone, which is a direct ligand for
peroxisome proliferator-activated receptor (PPAR) gamma, ameliorates insulin
resistance, we have demonstrated that PPAR gamma is expressed in a ...
Cited by 12 - Related articles - All 8 versions


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