B Emanuelli, M Glondu, C Filloux, P Peraldi, E Van … - Diabetes, 2004 - Am Diabetes Assoc Defects in insulin secretion, resulting from loss of function or destruction of pancreatic
ß-cells, trigger diabetes. Interleukin (IL)-1ß is a proinflammatory cytokine that is involved in type
1 and type 2 diabetes development and impairs ß-cell survival and function. Because ... Cited by 22 - Related articles - BL Direct - All 4 versions
F He, JM Stephens - Biochemical and Biophysical Research …, 2006 - Elsevier Insulin receptor substrate (IRS)-1 is a key protein in insulin signaling. Several studies have shown
that the expression of IRS-1 can be modulated by protein degradation via the proteasome and
the degradation of IRS-1 can be related to insulin-resistant states. The degradation of ... Cited by 6 - Related articles - All 4 versions
- ►endojournals.org SG Ronn, JA Hansen, K Lindberg, AE Karlsen, N … - Molecular …, 2002 - Endocrine Soc GH is an important regulator of cell growth and metabolism. In the pancreas, GH stimulates mitogenesis
as well as insulin production in ß-cells. The cellular effects of GH are exerted mainly through
activation of the Janus kinase-signal transducer and activator of transcription (STAT) ... Cited by 30 - Related articles - BL Direct - All 3 versions
A Marette - International journal of obesity and related metabolic …, 2003 - ncbi.nlm.nih.gov 1: Int J Obes Relat Metab Disord. 2003 Dec;27 Suppl 3:S46-8. Molecular mechanisms
of inflammation in obesity-linked insulin resistance. Marette A. Department of Anatomy
and Physiology, Lipid Research Unit, Laval University ... Cited by 10 - Related articles - BL Direct - All 3 versions
[CITATION] Interferon signaling in pancreatic-cells is persistent but can be terminated by …
AE Karlsen, PE Heding, H Frobøse, SG Rønn, M … - Diabetologia, 2004 - Springer Aims/hypothesis. The proinflammatory cytokine IL-1β induces apoptosis in pancreatic beta cells
via path- ways dependent on nuclear factor-κB (NF-κB), mito- gen-activated protein kinase, and
protein kinase C. We recently showed suppressor of cytokine signalling (SOCS)-3 to be a ... Cited by 25 - Related articles - All 3 versions
- ►endocrinology-journals.org K Lindberg, SG Ronn, D Tornehave, H … - Journal of molecular …, 2005 - Soc Endocrinology Growth hormone and prolactin are important growth factors for pancreatic ß-cells. The effects
exerted by these hormones on proliferation and on insulin synthesis and secretion in ß-cells
are largely mediated through the Janus kinase (JAK)/signal transducer and activator of ... Cited by 26 - Related articles - BL Direct - All 3 versions
[CITATION] Suppressor of cytokine signaling pancreatic islets: modulation by gene expression …
C Santangelo, A Scipioni, L Marselli, P Marchetti, F … - Eur J Endoc, 2005 Cited by 2 - Related articles
R Hepp, NJ Grant, S Chasserot-Golaz, D Aunis, K … - Journal of neurocytology, 2001 - Springer Page 1. Journal of Neurocytology 30, 789–800 (2001) The hypophysis controls expression of
SNAP-25 and other SNAREs in the adrenal gland R ´EGINE HEPP, NANCY J. GRANT, SYLVETTE
CHASSEROT-GOLAZ, DOMINIQUE AUNIS and KEITH LANGLEY ∗ ... Cited by 4 - Related articles - BL Direct - All 4 versions
- ►endojournals.org [PDF] J Jager, T Grémeaux, M Cormont, Y Le Marchand- … - Endocrinology, 2006 - Endocrine Soc Page 1. - 1 - INTERLEUKIN-1β−INDUCED INSULIN RESISTANCE IN ADIPOCYTES THROUGH
DOWN-REGULATION OF IRS-1 EXPRESSION Running Title: IL-1β and insulin resistance Jennifer
Jager, Thierry Grémeaux, Mireille Cormont , Yannick Le Marchand-Brustel, and ... Cited by 6 - Related articles - All 2 versions
