V Lyssenko, P Almgren, D Anevski, R Perfekt, K Lahti, … - Diabetes, 2005 - Am Diabetes Assoc Identification of individuals at high risk of developing type 2 diabetes is a prerequisite for prevention
of the disease. We therefore studied risk factors predicting type 2 diabetes in the Botnia Study
in western Finland. A total of 2,115 nondiabetic individuals were prospectively followed ... Cited by 96 - Related articles - All 7 versions
V Lyssenko, P Almgren, D Anevski, M Orho- … - PLoS …, 2005 - medicine.plosjournals.org By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN10
(SNP43 and 44), KCNJ11 (E23K), UCP2 (−866G>A), and IRS1 (G972R) genes were studied
for their ability to predict T2D in 2,293 individuals participating in the Botnia study in ... Cited by 63 - Related articles - Cached - BL Direct - All 10 versions
E Ferrannini, M Nannipieri, K Williams, C Gonzales, SM … - Diabetes, 2004 - Am Diabetes Assoc Fasting plasma glucose concentrations (FPG) predict development of type 2 diabetes. Whether
hyperglycemia evolves from normoglycemia gradually over time or as a step increase is not
known. We measured plasma glucose and insulin levels during oral glucose testing in ... Cited by 28 - Related articles - BL Direct - All 4 versions
L Groop, C Forsblom, M Lehtovirta, T Tuomi, S Karanko … - Diabetes, 1996 - Am Diabetes Assoc Although a strong genetic susceptibility has been established for NIDDM and a maternal transmission
of the disease predominates in some populations, a relationship between parental diabetes
status and metabolic abnormalities in nondiabetic offspring has not been shown in ... Cited by 204 - Related articles - BL Direct - All 4 versions
JC Bunt, J Krakoff, E Ortega, WC Knowler … - … research and reviews, 2007 - pubmedcentral.nih.gov Earlier prospective studies have identified insulin action and secretion as predictors of T2DM
in populations with normal glucose tolerance (NGT) and impaired glucose tolerance (IGT)
(2-h OGTT < 7.8 and 7.8-11 mmol/L, respectively). Fasting plasma glucose (FPG), an ... Cited by 7 - Related articles - BL Direct - All 4 versions
JC Florez, M Sjögren, N Burtt, M Orho-Melander, S … - Diabetes, 2004 - Am Diabetes Assoc The insulin receptor substrate (IRS)-1 is an important component of the insulin signal transduction
cascade. Several reports suggest that a Gly→Arg change in codon 972 is associated with type
2 diabetes and related traits, and a recent meta-analysis reported a modest but nominally ... Cited by 49 - Related articles - BL Direct - All 4 versions
V Lyssenko, A Jonsson, P Almgren, N Pulizzi … - The New England …, 2008 - nejm.highwire.org From the Department of Clinical Sciences, Lund University, Malmö, Sweden (VL, AJ, PA, GB,
PN, LG); the University of Pisa, Pisa, Italy (NP); the Folkhalsan Research Center (BI, TT) and
Helsinki University Central Hospital and the Uni- versity of Helsinki (TT, LG) — all in ... Cited by 58 - Related articles - All 4 versions
M Uusitupa, V Lindi, A Louheranta, T Salopuro, J … - Diabetes, 2003 - Am Diabetes Assoc Lifestyle interventions reduce the incidence of type 2 diabetes among individuals with impaired
glucose tolerance (IGT). However, it is unknown whether this is due to improved insulin sensitivity
or insulin secretion. We investigated at baseline insulin sensitivity and insulin secretion ... Cited by 80 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org AM Kanaya, CLW Fyr, N de Rekeneire, RI Shorr, … - Diabetes Care, 2005 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— A cross-sectional analysis with data from the Rancho
Bernardo Study (age 67 ± 11 years) to derive a rule predicting abnormal PCPG ≥140 mg/dl,
using demographic, clinical, and laboratory data of nondiabetic participants with fasting ... Cited by 34 - Related articles - All 6 versions
- ►diabetesjournals.org D Tripathy, P Almgren, T Tuomi, L Groop - Diabetes care, 2004 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—The homeostasis model assessment (HOMA) of insulin
resistance (IR) and the insulin sensitivity index (S i ) from oral glucose tolerance test (OGTT)
were compared with the M value from a hyperinsulinemic-euglycemic clamp in 467 ... Cited by 36 - Related articles - BL Direct - All 6 versions
