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Scholar Results 1 - 10 of about 101 related to Chen: Insulin deficiency downregulated heat shock protein 60 and IGF-1 receptor signaling.... (0.10 sec) 

Insulin deficiency downregulated heat shock protein 60 and IGF-1 receptor …


HS Chen, YX Shan, TL Yang, HD Lin, JW Chen, SJ Lin, … - Diabetes, 2005 - Am Diabetes Assoc
Heat shock protein (Hsp)60 and IGF-1 receptor signaling protect cardiac muscle against injury. The
abundance of cardiac IGF-1 receptor can be upregulated by Hsp60, but how diabetes modulates cardiac
muscle Hsp60 has not yet been ...
Cited by 30 - Related articles - All 6 versions

Hsp 10 and Hsp 60 Suppress Ubiquitination of Insulin-like Growth Factor-1 …


Y Shan, TL Yang, R Mestril, PH Wang - Journal of Biological Chemistry, 2003 - ASBMB
We have investigated the effects of two heat shock proteins, Hsp10 and Hsp60, on insulin-like growth
factor-1 receptor (IGF-1R) signaling in cardiac muscle cells. Neonatal cardiomyocytes were
transduced with Hsp10 or Hsp60 via ...
Cited by 32 - Related articles - BL Direct - All 4 versions

Regulation of IGF-I receptor signaling in diabetic cardiac muscle: dysregulation of …

- physiology.org
HC Lai, TJ Liu, CT Ting, JY Yang, L … - American Journal of …, 2007 - Am Physiological Soc
Insulin deficiency downregulates HSP60 and IGF-I receptor signaling and disrupts intracellular
signaling homeostasis in diabetic cardiac muscle. Our previous studies had shown that IGF-I
receptor signaling can be modulated by the abundance of HSP60. Since HSP60 localizes ...
Cited by 14 - Related articles - BL Direct - All 5 versions

Heat stress fails to protect myocardium of streptozotocin-induced diabetic rats …

- oxfordjournals.org
M Joyeux, P Faure, D Godin-Ribuot, … - Cardiovascular …, 1999 - cardiovascres.oxfordjournals.org
Objective: Protection conferred by heat stress (HS) against ischaemia–reperfusion injury, in term
of mechanical function and myocardial necrosis, has been extensively studied. In contrast, the
effects of disease states on this ...
Cited by 19 - Related articles - All 8 versions

Exercise training modulates heat shock protein response in diabetic rats

- physiology.org
M Atalay, NKJ Oksala, DE Laaksonen, S … - Journal of Applied …, 2004 - Am Physiological Soc
Strenuous exercise induces oxidative stress and modification of intracellular proteins. Exercise
training, however, upregulates endogenous antioxidant defenses and heat shock protein (HSP)
expression. In diabetes, ...
Cited by 58 - Related articles - BL Direct - All 7 versions

Decreased expression of heat shock protein 72 in skeletal muscle of patients with …

- diabetesjournals.org
I Kurucz, Á Morva, A Vaag, KF Eriksson, X Huang, L … - Diabetes, 2002 - Am Diabetes Assoc
Oxidative stress has been ascribed a role in the pathogenesis of diabetes and its complications, and
stress proteins have been shown to protect organisms in vitro and in vivo against oxidative stress.
To study the putative role of one ...
Cited by 46 - Related articles - BL Direct - All 4 versions

IGF-I is a matter of heart


OS Opgaard, PH Wang - Growth Hormone & IGF Research, 2005 - Elsevier
An intriguing relationship between IGF-I action and cardiac function has been noted for some time,
but exactly how IGF-I modulates myocardial function remained obscure. Recent research shed novel
insight into potential mechanisms ...
Cited by 14 - Related articles - All 2 versions

Association between plasma levels of heat shock protein 60 and cardiovascular …

- oxfordjournals.org
A Shamaei-Tousi, JW Stephens, R Bin, JA … - European heart …, 2006 - Eur Soc Cardiology
Methods and results A total of 855 patients with T1DM or T2DM, recruited as part of the UCL Diabetes
and Cardiovascular disease Study (UDACS), were assayed for plasma levels of Hsp60. Immunoreactive
Hsp60 was detected in 54% of the ...
Cited by 17 - Related articles - BL Direct - All 5 versions

Arm Muscle HSP70 Response to Strenght Training


M Brkic, Y Liu, A Schlumberger, K Wirth, D … - Medicine & Science in …, 2004 - journals.lww.com
Heat shock protein 70 (HSP70) expression in skeletal muscle is involved in a variety of muscular
changes including myopathy, muscle atrophy, muscle hypertrophy and ischemia.HSP70 plays an important
role in muscular adaptation to ...
Cited by 2 - Related articles

Ischemia induces HSP70 expression in porcine skeletal muscle


L Gampert, A Gebhardt, Y Liu, H Reinelt, M … - Medicine & Science in …, 2004 - journals.lww.com
1 Section of Sports and Rehabilitation Medicine, University of Ulm, Ulm, Germany. ... 2 Dept. of
Cardiac Anaesthesiology, University of Ulm, Ulm, Germany. ... Ischemia causing a series of cellular
changes is known to induce ...
Cited by 2 - Related articles


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