- ►nih.gov IG Obrosova, P Pacher, C Szabó, Z … - Diabetes, 2005 - Am Diabetes Assoc This study evaluated the effects of aldose reductase inhibition on
diabetes-induced oxidative-nitrosative stress and poly(ADP-ribose) polymerase
(PARP) activation. In animal experiments, control and ... Cited by 73 - Related articles - All 8 versions
IG Obrosova, F Li, OI Abatan, MA Forsell, K … - Diabetes, 2004 - Am Diabetes Assoc Oxidative and nitrosative stress play a key role in the pathogenesis of diabetic
neuropathy, but the mechanisms remain unidentified. Here we provide evidence
that poly(ADP-ribose) polymerase (PARP) activation, a downstream effector ... Cited by 87 - Related articles - BL Direct - All 10 versions
- ►inotekcorp.com [PDF] F Li, C Szabo, P Pacher, GJ Southan, OI … - Diabetologia, 2004 - Springer Aims/hypothesis. Poly(ADP-ribose) polymerase acti- vation depletes NAD + and
high-energy phosphates, activates protein kinase C, and affects gene expression
in various tissues. This study was designed to charac- terise the effects ... Cited by 38 - Related articles - BL Direct - All 11 versions
L Zheng, C Szabó, TS Kern - Diabetes, 2004 - Am Diabetes Assoc The current study investigated the role of poly(ADP-ribose) polymerase (PARP) in
the development of diabetic retinopathy. Activity of PARP was increased in whole
retina and in endothelial cells and pericytes of diabetic rats. ... Cited by 98 - Related articles - BL Direct - All 5 versions
- ►pubget.com [PDF] IG Obrosova, AG Minchenko, R Vasupuram, L … - Diabetes, 2003 - Am Diabetes Assoc The study addressed the role for aldose reductase (AR) in 1) retinal oxidative
stress and vascular endothelial growth factor (VEGF) overexpression in early
diabetes, and 2) high glucose-induced oxidative stress in retinal ... Cited by 83 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org F Li, VR Drel, C Szabó, MJ Stevens, IG … - Diabetes, 2005 - Am Diabetes Assoc Poly(ADP-ribose) polymerase (PARP) inhibition has recently been identified as a
novel approach to treatment of experimental peripheral diabetic neuropathy
(PDN). However, long-term inhibition of PARP, an enzyme involved in DNA ... Cited by 25 - Related articles - All 5 versions
- ►fasebj.org [PDF] AG Minchenko, MJ Stevens, L White, OI … - The FASEB Journal, 2003 - FASEB The FASEB Journal express article 10.1096/fj.03-0013fje. Published online June
3, 2003. ... Katalin Komjáti, fl,§ Pal Pacher, fl Csaba Szabó, fl and Irina
G. Obrosova † ... *Department of Anesthesiology Thomas Jefferson ... Cited by 67 - Related articles - BL Direct - All 7 versions
NE Cameron, Z Tuck, L McCabe, MA Cotter - Diabetologia, 2001 - Springer Page 1. Oxidative stress contributes to the neural and vascu- lar complications
of diabetes [1, 2]. For nerve, antiox- idant protection ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org C Cheng, DW Zochodne - Diabetes, 2003 - Am Diabetes Assoc Long-term experimental diabetes may best model the prominent and irreversible
sensory deficits of chronic human diabetic polyneuropathy. Whereas irretrievable
loss of sensory neurons, if present, would be an unfortunate feature of the ... Cited by 78 - Related articles - BL Direct - All 4 versions
