- ►diabetesjournals.org P Poulsen, K Levin, I Petersen, K … - Diabetes, 2005 - Am Diabetes Assoc The etiology of type 2 diabetes is multifactorial, including genetic as well as
pre- and postnatal factors that influence several different defects of glucose
homeostasis, primarily in muscle, β-cells, and liver. In the present twin ... Cited by 61 - Related articles - All 6 versions
P Poulsen, K Levin, H Beck-Nielsen, A Vaag - Diabetologia, 2002 - Springer Aims/hypothesis. Study the influence of age, zygosity and birth weight on
insulin action and insulin secre- tion in twins. Methods. In vivo insulin action
and insulin secretion were measured using the euglycaemic, hyperinsulin- ... Cited by 43 - Related articles - BL Direct - All 3 versions
- ►shouxi.net P Poulsen, A Vaag - Diabetes, 2006 - Am Diabetes Assoc According to the “fetal origins hypothesis,” monozygotic (MZ) twins may be
more prone to develop various metabolic abnormalities compared with dizygotic
(DZ) twins, and twins all together may be more predisposed to metabolic ... Cited by 25 - Related articles - BL Direct - All 5 versions
- ►endojournals.org H Storgaard, P Poulsen, C Ling, L Groop, AA … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Context: Insulin-stimulated glucose uptake in skeletal muscle is mediated
through translocation of the insulin-sensitive glucose transporter 4
(GLUT4)-containing vesicles to the plasma membrane. Thus, skeletal muscle ... Cited by 8 - Related articles - BL Direct - All 3 versions
N Morling - The Lancet, 2004 - Elsevier In crime casework today, there is an international consensus to investigate
repetitive DNA sequences in microsatellite regions—also called a short tandem
repeat (STR). Investigations are usually performed with enzymatic ... Cited by 13 - Related articles - All 4 versions
- ►diabetesjournals.org JM Lin, H Ortsäter, H Fakhrai-Rad, J Galli, H … - Diabetes, 2001 - Am Diabetes Assoc The major diabetes quantitative trait locus (Niddm1), which segregates in
crosses between GK rats affected with spontaneous type 2–like diabetes and
normoglycemic F344 rats, encodes at least two different diabetes ... Cited by 14 - Related articles - BL Direct - All 5 versions
M Lehtovirta, J Kaprio, C Forsblom, J Eriksson … - Diabetologia, 2000 - Springer There is plenty of evidence that Type II (non-insulin- dependent) diabetes
mellitusis a disease with a strong genetic predisposition [1ą3]. In Finland,
the estimat- ed lifetime relative risk (l) of developing diabetes for a ... Cited by 71 - Related articles - BL Direct - All 4 versions
- ►nih.gov C Ling, P Poulsen, E Carlsson, M … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig Genetic and environmental factors contribute to age-dependent susceptibility to
type 2 diabetes. Recent studies have reported reduced expression of PPARγ
coactivator 1α (PGC-1α) and PGC-1β genes in skeletal muscle from type 2 ... Cited by 111 - Related articles - BL Direct - All 9 versions
SM Clee, BS Yandell, KM Schueler, ME … - Nature - stat.wisc.edu We previously mapped the type 2 diabetes mellitus-2 locus (T2dm2), which affects
fasting insulin levels, to distal chromosome 19 in a leptin-deficient obese F2
intercross derived from C57BL/6 (B6) and BTBR T+ tf/J (BTBR) mice1. ... Cited by 46 - Related articles - View as HTML - BL Direct - All 12 versions
- ►bmj.com P Poulsen, A Vaag, H Beck-Nielsen - British Medical Journal, 1999 - bmj.com Several epidemiological and metabolic studies have shown a strong association
between low birth weight and the development of type 2 diabetes later in life.
1-4 Our finding of lower birth weights among monozygotic twins with type 2 ... Cited by 35 - Related articles - BL Direct - All 6 versions
