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Scholar Results 1 - 10 of about 101 related to Kared: Treatment With Granulocyte Colony− Stimulating Factor Prevents Diabetes in NOD Mice.... (0.11 sec) 

Treatment With Granulocyte Colony− Stimulating Factor Prevents Diabetes in NOD Mice by …

- diabetesjournals.org
H Kared, A Masson, H Adle-Biassette, JF … - Diabetes, 2005 - Am Diabetes Assoc
Accumulating evidence that granulocyte colony−stimulating factor (G-CSF), the
key hematopoietic growth factor of the myeloid lineage, not only represents a
major component of the endogenous response to infections, but also affects ...
Cited by 54 - Related articles - All 6 versions

Granulocyte colony-stimulating factor promotes the generation of regulatory DC through …


S Rutella, G Bonanno, L Pierelli, A Mariotti, … - European journal of immunology, 2004 - interscience.wiley.com
We have recently demonstrated that G-CSF promotes the generation of human T
regulatory (T REG ) type 1 cells. In this study, we investigated whether the
immunomodulatory effects of G-CSF might be mediated by DC. CD14 + monocytes ...
Cited by 46 - Related articles - BL Direct - All 3 versions

G-CSF treatment prevents cyclophosphamide acceleration of autoimmune diabetes in the …


K Hadaya, H Kared, A Masson, L Chatenoud, … - Journal of Autoimmunity, 2005 - Elsevier
Cyclophosphamide (CY) accelerates autoimmune diabetes in the NOD mouse at
different levels, including critical targeting of a regulatory T cell subset,
exacerbation of pro-Th1 IFN-γ production and promotion of inflammation in ...
Cited by 14 - Related articles - All 4 versions

Role for granulocyte colony-stimulating factor in the generation of human T regulatory type 1 …

- hematologylibrary.org
S Rutella, L Pierelli, G Bonanno, S Sica, F … - Blood, 2002 - bloodjournal.hematologylibrary.org
Herein we report that highly purified CD4 + T cells from healthy HSC donors
receiving G-CSF acquire the functional properties of Tr cells after activation
with alloantigens and secrete high amounts of IL-10 and moderate amounts of ...
Cited by 72 - Related articles - BL Direct - All 4 versions

Granulocyte-colony stimulating factor treatment of lupus autoimmune disease in MRL-lpr/lpr …

- jimmunol.org
F Zavala, A Masson, K Hadaya, S Ezine, E … - The Journal of Immunology, 1999 - Am Assoc Immnol
G-CSF not only functions as an endogenous hemopoietic growth factor for
neutrophils, but also displays pro-Th2 and antiinflammatory properties that
could be of therapeutic benefit in autoimmune settings. We evaluated the ...
Cited by 39 - Related articles - BL Direct - All 4 versions

Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice …

- jimmunol.org
S Gaudreau, C Guindi, M Menard, G Besin, G … - The Journal of Immunology, 2007 - Am Assoc Immnol
Autoimmune diabetes results from a breakdown of self-tolerance that leads to T
cell-mediated -cell destruction. Abnormal maturation and other defects of
dendritic cells (DCs) have been associated with the development of ...
Cited by 20 - Related articles - All 3 versions

G-CSF as immune regulator in T cells expressing the G-CSF receptor: implications for …

- hematologylibrary.org
A Franzke, W Piao, J Lauber, P Gatzlaff, C … - Blood, 2003 - bloodjournal.hematologylibrary.org
Results from experimental models, in vitro studies, and clinical data indicate
that granulocyte colony-stimulating factor (G-CSF) stimulation alters T-cell
function and induces Th2 immune responses. The immune modulatory effect of ...
Cited by 78 - Related articles - BL Direct - All 5 versions

Donor treatment with pegylated G-CSF augments the generation of IL-10-producing …

- hematologylibrary.org
ES Morris, K MacDonald, V Rowe, DH Johnson, … - Blood, 2004 - bloodjournal.hematologylibrary.org
Graft-versus-host disease (GVHD) remains a major complication following
allogeneic hemopoietic stem cell transplantation, with the resultant multiorgan
damage and immune deficiency significantly impairing overall ...
Cited by 69 - Related articles - BL Direct - All 5 versions

G-CSF therapy of ongoing experimental allergic encephalomyelitis via chemokine-and …

- jimmunol.org
F Zavala, S Abad, S Ezine, V Taupin, A … - The Journal of Immunology, 2002 - Am Assoc Immnol
Converging evidence that G-CSF, the hemopoietic growth factor of the myeloid
lineage, also exerts anti-inflammatory and pro-Th2 effects, prompted us to
evaluate its direct therapeutic potential in autoimmune diseases. Here we ...
Cited by 70 - Related articles - BL Direct - All 4 versions

Reduced IFN-α secretion by blood dendritic cells in human diabetes


KL Summers, AM Marleau, JL Mahon, R … - Clinical Immunology, 2006 - Elsevier
Characterization of dendritic cells (DC) in human diabetes has been restricted
to monocyte-derived DC in type 1 diabetes, whose physiological relevance to
endogenous DC is uncertain. Here, we provide the first report ...
Cited by 16 - Related articles - All 4 versions


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