- ►diabetesjournals.org S Papadopoulou, H Edlund - Diabetes, 2005 - Am Diabetes Assoc Mesenchymal-epithelial interactions are pivotal for proper pancreatic growth and
development. We have earlier shown that the fibroblast growth factor (FGF)
receptor 2 is expressed in pancreatic progenitor cells and that FGF10, the ... Cited by 57 - Related articles - BL Direct - All 6 versions
- ►biologists.org LC Murtaugh, AC Law, Y Dor, DA Melton - Development, 2005 - dev.biologists.org Despite our increasingly sophisticated understanding of transcriptional
regulation in pancreas development, we know relatively little about the
extrinsic signaling pathways involved in this process. We show here that ... Cited by 62 - Related articles - BL Direct - All 4 versions
- ►biologists.org PW Heiser, J Lau, MM Taketo, PL Herrera, M … - Development, 2006 - dev.biologists.org A recent study has shown that deletion of ß-catenin within the pancreatic
epithelium results in a loss of pancreas mass. Here, we show that ectopic
stabilization of ß-catenin within mouse pancreatic epithelium can have ... Cited by 57 - Related articles - BL Direct - All 5 versions
J Dessimoz, C Bonnard, J Huelsken, A Grapin … - Current Biology, 2005 - Elsevier Mutations and deregulation of adenomatous polyposis coli (APC) and β-catenin
are implicated in specific cancers of the pancreas, but the role of Wnt pathway
in normal pancreas development and homeostasis is unknown [1, 2, 3 and 4]. ... Cited by 54 - Related articles - All 10 versions
RS Heller, DS Dichmann, J Jensen, C Miller … - Developmental Dynamics, 2002 - interscience.wiley.com It is well established that gut and pancreas development depend on
epithelial-mesenchymal interactions. We show here that several Wnt, Frizzled,
and secreted frizzled-related protein (sFRP) encoding mRNAs are present ... Cited by 62 - Related articles - BL Direct - All 2 versions
JM Wells, F Esni, GP Boivin, BJ Aronow, W … - BMC developmental biology, 2007 - biomedcentral.com Pdx1-cre floxed β-catenin animals were viable but demonstrated small body size
and shortened median survival. The pancreata from knockout mice were hypoplastic
and histologically demonstrated a striking paucity of exocrine pancreas, ... Cited by 36 - Related articles - Cached - All 9 versions
- ►sciencemag.org IC Rulifson, SK Karnik, PW Heiser, D ten … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences There is widespread interest in defining factors and mechanisms that stimulate
proliferation of pancreatic islet cells. Wnt signaling is an important regulator
of organ growth and cell fates, and genes encoding Wnt-signaling factors ... Cited by 63 - Related articles - BL Direct - All 8 versions
RS Heller, T Klein, Z Ling, H Heimberg, M … - Gene expression, 2003 - ncbi.nlm.nih.gov Wnts are important signaling molecules involved in many normal developmental
processes in the human body as well as some forms of cancer. Nineteen Wnt genes
are found in the human genome, as well as 10 Wnt receptor genes called ... Cited by 57 - Related articles - BL Direct - All 2 versions
- ►biologists.org A Strom, C Bonal, R Ashery-Padan, N … - Development, 2007 - dev.biologists.org 1 Department of Genetic Medicine and Development, University of Geneva Faculty
of Medicine, 1 Rue Michel-Servet, CH-1211 Geneva 4, Switzerland. 2 Department of
Human Molecular Genetics and Biochemistry, Sackler School of Medicine, ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►shouxi.net S Cauchi, D Meyre, H Choquet, C Dina, C Born … - Diabetes, 2006 - Am Diabetes Assoc Recently, case-control studies demonstrated that a TCF7L2 (transcription factor
7–like 2 gene) noncoding variant (rs7903146 T at-risk allele) was strongly
associated with an increased risk of type 2 diabetes. However, the ... Cited by 54 - Related articles - BL Direct - All 4 versions
