- ►diabetesjournals.org GKC Brolén, N Heins, J Edsbagge, H Semb - Diabetes, 2005 - Am Diabetes Assoc The recent success in restoring normoglycemia in type 1 diabetes by islet cell
transplantation indicates that cell replacement therapy of this severe disease
is achievable. However, the severe lack of donor islets has increased the ... Cited by 79 - Related articles - BL Direct - All 6 versions
- ►alphamedpress.org P Vaca, F Martin, JM Vegara-Meseguer, JM … - Stem Cells, 2006 - AlphaMed Press Cell signals produced during pancreas embryogenesis regulate pancreatic
differentiation. We show that the developing pancreas releases soluble factors
responsible for in vitro endocrine pancreatic differentiation from ... Cited by 51 - Related articles - BL Direct - All 8 versions
M Hansson, A Tonning, U Frandsen, A Petri, J … - Diabetes, 2004 - Am Diabetes Assoc Several recent reports claim the generation of insulin-producing cells from
embryonic stem cells via the differentiation of progenitors that express nestin.
Here, we investigate further the properties of these insulin-containing ... Cited by 137 - Related articles - BL Direct - All 4 versions
- ►alphamedpress.org H Segev, B Fishman, A Ziskind, M Shulman, J … - Stem Cells, 2004 - AlphaMed Press The protocol consisted of several steps. Embryoid bodies were first cultured and
plated in insulin-transferrin-selenium-fibronectin medium, followed by medium
supplemented with N2, B27, and basic fibroblast growth factor (bFGF). Next, ... Cited by 215 - Related articles - BL Direct - All 7 versions
X Xu, B Kahan, A Forgianni, P Jing, L … - Cloning and Stem Cells, 2006 - liebertonline.com Human embryonic stem cells (HESCs) are a potential source of insulin-producing
tissue for transplantation. Recent studies have begun to define factors that
promote definitive endo- derm formation from HESCs, but conditions ... Cited by 25 - Related articles - BL Direct - All 4 versions
W Jiang, Y Shi, D Zhao, S Chen, J Yong, J … - Cell Research, 2007 - nature.com The capacity for self-renewal and differentiation of human embryonic stem (ES)
cells makes them a potential source for generation of pancreatic beta cells for
treating type I diabetes mellitus. Here, we report a newly developed and ... Cited by 44 - Related articles - BL Direct - All 7 versions
S Sipione, A Eshpeter, JG Lyon, GS Korbutt, … - Diabetologia, 2004 - Springer Aim/hypothesis. Embryonic stem (ES) cells have been proposed as a potential
source of tissue for transplan- tation for the treatment of Type 1 diabetes.
However, studies showing differentiation of beta cells from ES cells are ... Cited by 122 - Related articles - BL Direct - All 6 versions
- ►alphamedpress.org Y Shi, L Hou, F Tang, W Jiang, P Wang, M … - Stem Cells, 2005 - AlphaMed Press Experimental induction of embryonic stem cells (ESCs) to become pancreatic ß
cells can potentially provide ample resource for cell transplantation therapy of
type I diabetes mellitus. Most of the previously reported induction ... Cited by 94 - Related articles - All 6 versions
- ►diabetesjournals.org S Miyazaki, E Yamato, J Miyazaki - Diabetes, 2004 - Am Diabetes Assoc Embryonic stem (ES) cells can differentiate into many cell types. Recent reports
have shown that ES cells can differentiate into insulin-producing cells.
However, the differentiation is not efficient enough to produce insulin- ... Cited by 152 - Related articles - BL Direct - All 4 versions
BW Kahan, LM Jacobson, DA Hullett, JM … - Diabetes, 2003 - Am Diabetes Assoc Embryonic stem (ES) cells differentiating in vitro reproduce many facets of
early embryonic development, including the expression of developmentally
regulated transcription factors and the differentiation of multipotent ... Cited by 100 - Related articles - BL Direct - All 6 versions
