- ►diabetesjournals.org K Ichinose, Y Maeshima, Y Yamamoto, H Kitayama, Y … - Diabetes, 2005 - Am Diabetes Assoc Diabetic nephropathy is one of the major microvascular complications in diabetes and is the
leading cause of end-stage renal disease worldwide. Among various factors, angiogenesis-associated
factors such as vascular endothelial growth factor (VEGF)-A and angiopoietin (Ang)-2 are ... Cited by 40 - Related articles - BL Direct - All 6 versions
K Ichinose, Y Maeshima, Y Yamamoto, M Kinomura, K … - Diabetes, 2006 - Am Diabetes Assoc One of the mechanisms involved in the progression of diabetic nephropathy, the most common
cause of end-stage renal failure, is angiogenic phenomenon associated with the increase of
angiogenic factors such as vascular endothelial growth factor (VEGF)-A and angiopoietin ( ... Cited by 15 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org Y Yamamoto, Y Maeshima, H Kitayama, S Kitamura, Y … - Diabetes, 2004 - Am Diabetes Assoc In the early stage of diabetic nephropathy (one of the major microvascular complications of
diabetes) glomerular hyperfiltration and hypertrophy are observed. It is clinically important to
regulate glomerular hypertrophy for preventing glomerulosclerosis. The number of ... Cited by 84 - Related articles - BL Direct - All 6 versions
Y Kanesaki, D Suzuki, G Uehara, M Toyoda, T … - American Journal of …, 2005 - Elsevier Background: In diabetic nephropathy (DN) small vessels are frequently observed around the
glomerular vascular pole in addition to normal afferent and efferent arterioles; this is regarded
as neovascularization. Because vascular endothelial growth factor (VEGF) promotes ... Cited by 35 - Related articles - All 8 versions
- ►asnjournals.org SX Zhang, JJ Wang, K Lu, R Mott, R … - Journal of the American …, 2006 - Am Soc Nephrol Angiostatin is a proteolytic fragment of plasminogen and a potent angiogenic inhibitor. Previous
studies have shown that angiostatin inhibits retinal neovascularization and reduces retinal vascular
permeability in diabetic retinopathy. Here, it is reported for the first time that angiostatin is ... Cited by 21 - Related articles - BL Direct - All 6 versions
K Tanabe, Y Maeshima, K Ichinose, H Kitayama, Y … - Kidney international, 2006 - nature.com Peritoneal sclerosis is a major and serious complication in patients on long-term continuous
ambulatory peritoneal dialysis (PD). The involvement of angiogenesis and proangiogenic factors
such as vascular endothelial growth factor (VEGF)-A in progressing peritoneal sclerosis ... Cited by 13 - Related articles - BL Direct - All 3 versions
- ►oxfordjournals.org BF Schrijvers, A Flyvbjerg, RG Tilton, NH Lameire … - Nephrology Dialysis …, 2006 - ERA-EDTA Background. Antagonism of vascular endothelial growth factor (VEGF) has improved the outcome
in experimental nephropathies of various origins, including diabetic nephropathy in a type 1
diabetic rat model and a type 2 diabetic mouse model. Neutralizing VEGF antibodies ... Cited by 27 - Related articles - BL Direct - All 5 versions
H Makino, N Kashihara, H Sugiyama, K Kanao, T … - Diabetes, 1996 - Am Diabetes Assoc The phenotypic change of the mesangial cell is considered to play a pivotal role in the accumulation
of extracellular matrix in diabetic nephropathy. This investigation was undertaken to evaluate
the expression of the various isoforms of contractile proteins in the streptozocin (STZ)- ... Cited by 71 - Related articles - All 4 versions
MP Cohen, S Chen, FN Ziyadeh, E Shea, EA Hud, GT … - Kidney international, 2005 - nature.com Albumin modified by Amadori-glucose adducts has been linked to the development of diabetic
nephropathy through its ability, independent of hyperglycemia, to activate protein kinase C-
(PKC- ), up-regulate the transforming growth factor- (TGF- ) system, and stimulate ... Cited by 35 - Related articles - BL Direct - All 4 versions
B Rizkalla, JM Forbes, Z Cao, G Boner, ME … - Journal of …, 2005 - journals.lww.com Objective: It has been postulated that vascular endothelial growth factor (VEGF) plays a role
in the progression of renal injury. However, the role of other angiogenic factors and their
receptors, such as the angiopoietins and Tie2, and in particular their relation to ... Cited by 16 - Related articles - All 3 versions
