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Scholar Results 1 - 10 of about 101 related to Plomgaard: Tumor necrosis factor-α induces skeletal muscle insulin resistance in healthy.... (0.31 sec) 

Tumor necrosis factor-α induces skeletal muscle insulin resistance in healthy human subjects …

- diabetesjournals.org
P Plomgaard, K Bouzakri, R Krogh-Madsen, B … - Diabetes, 2005 - Am Diabetes Assoc
Most lifestyle-related chronic diseases are characterized by low-grade systemic
inflammation and insulin resistance. Excessive tumor necrosis factor-α (TNF-α)
concentrations have been implicated in the development of insulin ...
Cited by 102 - Related articles - BL Direct - All 4 versions

Tumor necrosis factor-induces skeletal muscle insulin resistance in healthy human subjects …

- shouxi.net
P Plomgaard, K Bouzakri, R Krogh-Madsen, B … - Diabetes, 2005 - Am Diabetes Assoc
Most lifestyle-related chronic diseases are characterized by low-grade systemic
inflammation and insulin resistance. Excessive tumor necrosis factor- (TNF- )
concentrations have been implicated in the development of insulin resis- ...
Cited by 29 - Related articles - All 4 versions

MAP4K4 Gene Silencing in Human Skeletal Muscle Prevents Tumor Necrosis Factor-{alpha}- …

- jbc.org
K Bouzakri, JR Zierath - Journal of Biological Chemistry, 2007 - ASBMB
Tumor necrosis factor- (TNF- ) induces skeletal muscle insulin resistance by
impairing insulin signaling events involved in GLUT4 translocation. We tested
whether mitogenic-activated protein kinase kinase kinase kinase isoform 4 ( ...
Cited by 36 - Related articles - All 7 versions

Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and …

- shouxi.net
AL Carey, GR Steinberg, SL Macaulay, WG … - Diabetes, 2006 - Am Diabetes Assoc
Although interleukin-6 (IL-6) has been associated with insulin resistance,
little is known regarding the effects of IL-6 on insulin sensitivity in humans
in vivo. Here, we show that IL-6 infusion increases glucose disposal ...
Cited by 97 - Related articles - BL Direct - All 6 versions

Acute interleukin-6 administration does not impair muscle glucose uptake or whole-body …

- nih.gov
A Steensberg, CP Fischer, M Sacchetti, C … - The Journal of Physiology, 2003 - Physiological Soc
The cytokine interleukin (IL)-6 has recently been linked with type 2 diabetes
mellitus and has been suggested to affect glucose metabolism. To determine
whether acute IL-6 administration affects whole-body glucose kinetics or ...
Cited by 86 - Related articles - BL Direct - All 9 versions

Tumor necrosis factor α produces insulin resistance in skeletal muscle by activation of …


C De Alvaro, T Teruel, R Hernandez, M … - Journal of Biological Chemistry, 2004 - ASBMB
Insulin stimulation produced a reliable 3-fold increase in glucose uptake in
primary neonatal rat myotubes, which was accompanied by a similar effect on
GLUT4 translocation to plasma membrane. Tumor necrosis factor (TNF)-α ...
Cited by 142 - Related articles - BL Direct - All 4 versions

Acute IL-6 treatment increases fatty acid turnover in elderly humans in vivo and in tissue …

- physiology.org
EW Petersen, AL Carey, M Sacchetti, GR … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc
To determine whether IL-6 increases lipolysis and fat oxidation in patients with
type 2 diabetes and/or whether it exerts this effect independently of changes to
the hormonal milieu, patients with type 2 diabetes (D) and healthy control ...
Cited by 62 - Related articles - All 6 versions

Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and …

- jbc.org
C Huang, ACP Thirone, X Huang, A Klip - Journal of Biological Chemistry, 2005 - ASBMB
Insulin receptor substrates-1 and 2 (IRS-1 and IRS-2) are pivotal in relaying
insulin signaling in insulin-responsive tissues such as muscle. However, the
precise contribution of IRS-1 vis-à-vis IRS-2 in insulin-mediated ...
Cited by 57 - Related articles - All 5 versions

Influence of TNF-{alpha} and IL-6 infusions on insulin sensitivity and expression of IL-18 in …

- physiology.org
R Krogh-Madsen, P Plomgaard, K Moller, B … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
Inflammation is associated with insulin resistance, and both tumor necrosis
factor (TNF)- and interleukin (IL)-6 may affect glucose uptake. TNF induces
insulin resistance, whereas the role of IL-6 is controversial. High plasma ...
Cited by 43 - Related articles - BL Direct - All 3 versions

Cytokine regulation of skeletal muscle fatty acid metabolism: effect of interleukin-6 and tumor …

- physiology.org
CR Bruce, DJ Dyck - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc
IL-6 and TNF- have been associated with insulin resistance and type 2 diabetes.
Furthermore, abnormalities in muscle fatty acid (FA) metabolism are strongly
associated with the development of insulin resistance. However, few studies ...
Cited by 55 - Related articles - BL Direct - All 4 versions


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