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Scholar Results 1 - 10 of about 101 related to Pedchenko: Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive.... (0.08 sec) 

Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive …

- diabetesjournals.org
VK Pedchenko, SV Chetyrkin, P Chuang, AJL Ham, MA … - Diabetes, 2005 - Am Diabetes Assoc
Perturbation of interactions between cells and the extracellular matrix (ECM) of renal glomeruli
may contribute to characteristic histopathological lesions found in the kidneys of patients with
diabetic nephropathy. However, the mechanism by which the diabetic conditions may ...
Cited by 24 - Related articles - BL Direct - All 7 versions

Angiotensin II-induced podocyte apoptosis: role of the MAPK subtypes


XX Lai, GH Ding, CX Huang, M Shi, C … - Beijing da xue xue bao. Yi …, 2004 - ncbi.nlm.nih.gov
OBJECTIVE: To evaluate the role of the MAPK subtypes (p38MAPK, ERK and JNK) in ANG
II-induced apoptosis of cultured human podocytes. METHODS: The cultured podocytes were
incubated in media containing either vehicle, SB202190(5 micromol/L, an inhibitor of ...
Cited by 5 - Related articles

Integrin-mediated interactions between primary/T-SV 40 immortalized human …


U Krishnamurti, Y Chen, A Michael, Y Kim, WW Fan, … - Laboratory …, 1996 - cat.inist.fr
The use of human glomerular epithelial cells(HGEC) in research has been severely restricted
by several obstacles, which have been circumvented by the generation of T-SV 40 immortalized
human visceral glomerular epithelial cells(Delarue et al, 1991). In this work, we compared ...
Cited by 30 - Related articles - BL Direct - All 2 versions

[CITATION] The role of the podocyte in the degeneration of a renal glomerulus.


W Kriz - Advances in nephrology from the Necker Hospital, 1997 - ncbi.nlm.nih.gov
1: Adv Nephrol Necker Hosp. 1997;27:1-13. The role of the podocyte in the
degeneration of a renal glomerulus. Kriz W. Institut für Anatomie und Zellbiologie,
Universität Heidelberg, Germany. Publication Types: Research Support ...
Cited by 10 - Related articles - BL Direct

Threonine 788 in integrin subunit β1 regulates integrin activation


S Nilsson, D Kaniowska, C Brakebusch, R Fässler, S … - Experimental cell …, 2006 - Elsevier
In the present study, the functional role of suggested phosphorylation of the conserved threonines
in the cytoplasmic domain of integrin subunit β1 was investigated. Mutants mimicking phosphorylated
and unphosphorylated forms of β1 were expressed in β1 deficient GD25 cells. T788 in β1 ...
Cited by 11 - Related articles - All 5 versions

Differential expression of collagen-and laminin-binding integrins mediates ureteric …

- physiology.org [PDF] 
D Chen, R Roberts, M Pohl, S Nigam, J … - American Journal of …, 2004 - Am Physiological Soc
24 articles, 11 of which you can access free at: This article cites http://ajprenal.physiology.org
/cgi/content/full/287/4/F602#BIBL ... 10 other HighWire hosted articles, the first 5 are: This article
has been cited by ... [PDF] [Full Text] [Abstract] , November 1, 2007; 18 (11): 4446-4456. ...
Cited by 24 - Related articles - BL Direct - All 5 versions

Glomerular injury is exacerbated in diabetic integrin α1-null mice


R Zent, X Yan, Y Su, BG Hudson, DB Borza, GW … - Kidney international, 2006 - nature.com
Excessive glomerular collagen IV and reactive oxygen species (ROS) production are key factors
in the development of diabetic nephropathy. Integrin 1 1, the major collagen IV receptor, dowregulates
collagen IV and ROS production, suggesting this integrin might determine the severity of ...
Cited by 14 - Related articles - BL Direct - All 3 versions

Stress proteins in glomerular epithelial cell injury


K Bijian, AV Cybulsky - Contributions to Nephrology, 2005 - content.karger.com
Abstract Glomerular visceral epithelial cells (GEC) or podocytes are highly differentiated,
spe- cialized cells that play a key role in the maintenance of glomerular permselectivity. Injury
of GEC, leading to proteinuria, contributes to the pathogenesis of human and ...
Cited by 15 - Related articles - All 5 versions

Lack of Integrin {alpha} 1 {beta} 1 Leads to Severe Glomerulosclerosis after …

- amjpathol.org
X Chen, G Moeckel, JD Morrow, D Cosgrove, RC … - American Journal of …, 2004 - ASIP
Severity of fibrosis after injury is determined by the nature of the injury and host genetic
susceptibility. Metabolism of collagen, the major component of fibrotic lesions, is, in part, regulated
by integrins. Using a model of glomerular injury by adriamycin, which induces reactive ...
Cited by 29 - Related articles - BL Direct - All 4 versions

Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces …

- diabetesjournals.org
D Dobler, N Ahmed, L Song, KE Eboigbodin, PJ … - Diabetes, 2006 - Am Diabetes Assoc
Chronic vascular disease in diabetes is associated with disruption of extracellular matrix
(ECM) interactions with adherent endothelial cells, compromising cell survival and impairing
vasculature structure. Loss of functional contact with integrins activates anoikis and ...
Cited by 31 - Related articles - BL Direct - All 5 versions


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