- ►shouxi.net E Carlsson, P Poulsen, H Storgaard, P … - Diabetes, 2005 - Am Diabetes Assoc The gene encoding calpain-10 (CAPN10) has been identified as a candidate gene
for type 2 diabetes. Our aim was to study the impact of genetic (heritability
and polymorphisms) and nongenetic (insulin, free fatty acids, and age) ... Cited by 21 - Related articles - BL Direct - All 5 versions
LJ Logie, AE Brown, SJ Yeaman, M Walker - Molecular Genetics and Metabolism, 2005 - Elsevier Variation in the calpain 10 gene has been reported to increase susceptibility to
type 2 diabetes. Part of this susceptibility appears to be mediated by a
decrease in whole body insulin sensitivity. As skeletal muscle is the ... Cited by 15 - Related articles - All 3 versions
MD Turner, FK Fulcher, CV Jones, BT Smith, E … - Biochemical and biophysical research communications, 2007 - Elsevier Calpain-10 (CAPN10) has been identified as a diabetes susceptibility gene.
Previous studies have shown that alterations in calpain activity alter both
glucose uptake and insulin secretion. In this report, we investigated the ... Cited by 11 - Related articles - All 6 versions
- ►endojournals.org E Carlsson, J Fredriksson, L Groop, M … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Our aim was to investigate the possible role of the type 2 diabetes
susceptibility gene CAPN10 in obesity. A case control study consisting of 235
obese Swedish subjects [body mass index, 40 (35–45) kg/m 2 ] and 235 ... Cited by 41 - Related articles - BL Direct - All 4 versions
AE Brown, SJ Yeaman, M Walker - Molecular Genetics and Metabolism, 2007 - Elsevier Calpain-10 was identified as a novel type 2 diabetes susceptibility gene,
although the mechanisms by which it increases susceptibility to type 2 diabetes
remain unclear. As skeletal muscle is the principal site of the peripheral ... Cited by 7 - Related articles - All 3 versions
L Norton, T Parr, RG Bardsley, H Ye, K … - Acta Physiologica, 2007 - viking.nottingham.ac.uk Received 4 September 2006, revision requested 5 October 2006, revision received
10 October 2006, accepted 10 October 2006 Correspondence: Dr K. Tsintzas, School
of Biomedical Sciences, Nottingham University Medical School, Queen's ... Cited by 7 - Related articles - View as HTML - BL Direct - All 6 versions
- ►endojournals.org C Marshall, GA Hitman, CJ Partridge, A Clark … - Molecular Endocrinology, 2005 - Endocrine Soc Calpain-10 (CAPN10) is the first type 2 diabetes susceptibility gene to be
identified through a genome scan, with polymorphisms being associated with
altered CAPN10 expression. Functional data have been hitherto elusive, but ... Cited by 49 - Related articles - All 5 versions
[CITATION] Common variants in the TCF7L2 gene increase risk of future type 2 diabetes by influencing …
DS Paul, AW Harmon, CP Winston, YM Patel - Biochemical Journal, 2003 - bj.portlandpress.com Calpains are a family of non-lysosomal cysteine proteases. Recent studies have
identified a member of the calpain family of proteases, calpain 10, as a
putative diabetes-susceptibility gene that may be involved in the ... Cited by 48 - Related articles - View as HTML - BL Direct - All 10 versions
X Yang, RE Pratley, LJ Baier, Y Horikawa, GI … - Molecular genetics and metabolism, 2001 - Elsevier The DNA polymorphism SNP-43 in the calpain-10 gene is associated with insulin
resistance and reduced skeletal muscle transcript in Pima Indians. Alternative
splicing generates transcript isoforms calpain-10a to -10h. We determined ... Cited by 34 - Related articles - BL Direct - All 4 versions
