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Scholar Results 1 - 10 of about 101 related to Coward: The human glomerular podocyte is a novel target for insulin action. (0.12 sec) 

The human glomerular podocyte is a novel target for insulin action


RJM Coward, GI Welsh, J Yang, C Tasman, R … - Diabetes, 2005 - Am Diabetes Assoc
Microalbuminuria is significant both as the earliest stage of diabetic
nephropathy and as an independent cardiovascular risk factor in nondiabetic
subjects, in whom it is associated with insulin resistance. The link ...
Cited by 36 - Related articles - BL Direct - All 11 versions

Nephrin is critical for the action of insulin on human glomerular podocytes


RJM Coward, GI Welsh, A Koziell, S Hussain, … - Diabetes, 2007 - Am Diabetes Assoc
The leading causes of albuminuria and end-stage renal failure are secondary to
abnormalities in the production or cellular action of insulin, including
diabetes and hyperinsulinemic metabolic syndrome. The human glomerular ...
Cited by 20 - Related articles - BL Direct - All 5 versions

Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy …


T Tejada, P Catanuto, A Ijaz, JV Santos, X Xia … - Kidney International, 2008 - nature.com
Loss of podocytes by apoptosis characterizes the early stages of diabetic
nephropathy. To examine its mechanism we studied glomeruli and podocytes
isolated from db/db mice with early diabetic nephropathy and albuminuria. ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, …

- asnjournals.org
RJM Coward, RR Foster, D Patton, L Ni, R … - Journal of the American Society of Nephrology, 2005 - Am Soc Nephrol
Podocytes are critical in maintaining the filtration barrier of the glomerulus
and are dependent on the slit diaphragm (SD) proteins nephrin, podocin, and
CD2-associated protein (CD2AP) to function optimally. The effects of normal ...
Cited by 42 - Related articles - All 6 versions

Mechanical strain increases SPARC levels in podocytes: implications for glomerulosclerosis

- physiology.org [PDF] 
RV Durvasula, SJ Shankland - American Journal of Physiology- Renal Physiology, 2005 - Am Physiological Soc
42 articles, 15 of which you can access free at: This article cites
http://ajprenal.physiology.org/cgi/content/full/289/3/F577#BIBL ... 6 other
HighWire hosted articles, the first 5 are: This article has been cited by
Cited by 16 - Related articles - BL Direct - All 5 versions

Characterization of glucose uptake by cultured rat podocytes


B Lewko, E Bryl, JM Witkowski, E Latawiec, M … - Kidney Blood Press Res, 2005 - content.karger.com
Barbara Lewko a, c Ewa Bryl b Jacek M. Witkowski b El z ˙ bieta Latawiec a
Magdalena Gołos a Nicole Endlich d Brunhilde Hähnel d Claudia Koksch d ...
Stefan Angielski a, c Wilhelm Kriz d Jan Stepinski a, c
Cited by 6 - Related articles - All 6 versions

Obesity and insulin resistance as risk factors for chronic kidney disease


A Whaley-Connell, BS Pavey, A Afroze, GL … - J Cardiometab Syndr, 2006 - interscience.wiley.com
The cardiometabolic syndrome is a state of metabolic and vascular dysregulation.
The cardiometabolic syndrome is clinically composed of a cluster of metabolic
abnormalities including insulin resistancelhyperinsulinemia, ...
Cited by 10 - Related articles

Spectrum of renal diseases associated with extreme forms of insulin resistance

- asnjournals.org
C Musso, E Javor, E Cochran, JE Balow, P … - Clinical Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol
Diabetic nephropathy is the leading cause of ESRD in the United States. Why the
pathogenic mechanisms lead to nephropathy in certain patients with type 1 and 2
diabetes and spare others is unclear, but it is clear that hyperglycemia ...
Cited by 9 - Related articles - BL Direct - All 4 versions

High glucose and advanced glycosylated end-products affect the expression of α-actinin-4 in …


TS Ha - Nephrology, 2006 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
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degraded, the site should continue to be functional. We recommend using the ...
Cited by 10 - Related articles - BL Direct - All 3 versions

Podocyte biology in diabetic nephropathy


JJ Li, SJ Kwak, DS Jung, JJ Kim, TH Yoo, … - Kidney International, 2007 - nature.com
Glomerular visceral epithelial cells, namely podocytes, are highly specialized
cells and give rise to primary processes, secondary processes, and finally foot
processes. The foot processes of neighboring podocytes interdigitate, ...
Cited by 16 - Related articles - BL Direct - All 3 versions


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