- ►diabetesjournals.org D Langin, A Dicker, G Tavernier, J Hoffstedt, A Mairal, … - Diabetes, 2005 - Am Diabetes Assoc The mobilization of fat stored in adipose tissue is mediated by hormone-sensitive lipase
(HSL) and the recently characterized adipose triglyceride lipase (ATGL), yet their relative importance
in lipolysis is unknown. We show that a novel potent inhibitor of HSL does not inhibit other ... Cited by 88 - Related articles - BL Direct - All 5 versions
A Mairal, D Langin, P Arner, J Hoffstedt - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 1629–1636 DOI 10.1007/s00125-006-0272-x ARTICLE A. Mairal .
D. Langin . P. Arner . J. Hoffstedt Human adipose triglyceride lipase (PNPLA2) is not regulated
by obesity and exhibits low in vitro triglyceride hydrolase activity ... Cited by 38 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org EE Kershaw, JK Hamm, LAW Verhagen, O Peroni, M … - Diabetes, 2006 - Am Diabetes Assoc Adipose triglyceride lipase (ATGL) is a recently described adipose-enriched protein with
triglyceride-specific lipase activity. ATGL shares the greatest sequence homology with
adiponutrin, a nutritionally regulated protein of unclear biological function. Here we ... Cited by 77 - Related articles - BL Direct - All 6 versions
- ►physiology.org M Ryden, J Jocken, V van Harmelen, A … - American Journal of …, 2007 - Am Physiological Soc Hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL) regulate adipocyte lipolysis
in rodents. The purpose of this study was to compare the roles of these lipases for lipolysis in
human adipocytes. Subcutaneous adipose tissue was investigated. HSL and ATGL ... Cited by 32 - Related articles - BL Direct - All 5 versions
- ►jbc.org M Schweiger, R Schreiber, G Haemmerle, A Lass, … - Journal of Biological …, 2006 - ASBMB The mobilization of free fatty acids from adipose triacylglycerol (TG) stores requires the activities
of triacylglycerol lipases. In this study, we demonstrate that adipose triglyceride lipase
(ATGL) and hormone-sensitive lipase (HSL) are the major enzymes contributing to TG ... Cited by 89 - Related articles - All 6 versions
JA Villena, S Roy, E Sarkadi-Nagy, KH Kim, HS … - Journal of Biological …, 2004 - ASBMB We have used rat cDNA microarrays to identify adipocyte-specific genes that could play an important
role in adipocyte differentiation or function. Here, we report the cloning and identification of a
2.0-kb mRNA coding for a putative protein that we have designated as desnutrin. The ... Cited by 169 - Related articles - BL Direct - All 6 versions
- ►cell.com A Lass, R Zimmermann, G Haemmerle, M Riederer, G … - Cell Metabolism, 2006 - Elsevier Adipose triglyceride lipase (ATGL) was recently identified as an important triacylglycerol
(TG) hydrolase promoting the catabolism of stored fat in adipose and nonadipose tissues. We
now demonstrate that efficient ATGL enzyme activity requires activation by CGI-58. ... Cited by 121 - Related articles - All 13 versions
S Kralisch, J Klein, U Lossner, M Bluher, R Paschke … - Molecular and Cellular …, 2005 - Elsevier Recently, adipose triglyceride lipase (ATGL, also called desnutrin and calcium-independent
phospholipase A2 [iPLA 2 ] ζ) was isolated as a novel adipose-expressed triglyceride lipase
which is downregulated in obesity and may contribute to obesity-associated metabolic ... Cited by 46 - Related articles - All 3 versions
- ►meduni-graz.at [PDF] G Haemmerle, A Lass, R Zimmermann, G Gorkiewicz, … - Science, 2006 - sciencemag.org Fat tissue is the most important energy depot in vertebrates. The release of free fatty acids
(FFAs) from stored fat requires the enzymatic activity of lipases. We showed that genetic inactivation
of adipose triglyceride lipase (ATGL) in mice increases adipose mass and leads to ... Cited by 170 - Related articles - BL Direct - All 11 versions
- ►jbc.org JG Granneman, HPH Moore, RL Granneman, AS … - Journal of Biological …, 2007 - ASBMB This work examined the colocalization, trafficking, and interactions of key proteins involved in
lipolysis during brief cAMP-dependent protein kinase A (PKA) activation. Double label immunofluorescence
analysis of 3T3-L1 adipocytes indicated that PKA activation increases the translocation of ... Cited by 73 - Related articles - All 9 versions
