- ►diabetesjournals.org J Yang, CE Robert, BR Burkhardt, RA Young, … - Diabetes, 2005 - Am Diabetes Assoc Pancreatic-derived factor (PANDER) is an islet-specific cytokine present in both
pancreatic α- and β-cells, which, in vitro, induces β-cell apoptosis of
primary islet and cell lines. In this study, we investigated whether PANDER ... Cited by 15 - Related articles - BL Direct - All 5 versions
BR Burkhardt, MC Yang, CE Robert, SR … - BBA-Gene Structure and Expression, 2005 - Elsevier Pancreatic derived factor (PANDER) is a recently identified cytokine-like
protein that is dominantly expressed in the islets of Langerhans of the
pancreas. To investigate the mechanism of tissue-specific regulation of ... Cited by 12 - Related articles - All 4 versions
X Cao, Z Gao, CE Robert, S Greene, G Xu, W … - Diabetes, 2003 - Am Diabetes Assoc PANDER (PANcreatic DERived factor, FAM3B), a newly discovered secreted cytokine,
is specifically expressed at high levels in the islets of Langerhans of the
endocrine pancreas. To evaluate the role of PANDER in β-cell function, we ... Cited by 23 - Related articles - BL Direct - All 5 versions
W Xu, Z Gao, J Wu, BA Wolf - Molecular and cellular endocrinology, 2005 - Elsevier The pancreatic-derived factor (PANDER, FAM3B) is a novel protein that is β-cell
specific and induces β-cell death. PANDER is localized to insulin-containing
granules-based on confocal microscopy and immunogold electron microscopy. ... Cited by 12 - Related articles - All 4 versions
- ►physiology.org X Cao, J Yang, BR Burkhardt, Z Gao, RK … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc PANcreatic DERived factor (PANDER, FAM3B) is a recently discovered
islet-specific cytokine. We have previously shown that, in vitro, truncated
recombinant PANDER isoforms (20 and 21 kDa) are cytotoxic to -cell lines ... Cited by 11 - Related articles - BL Direct - All 4 versions
- ►endojournals.org O Wang, K Cai, S Pang, T Wang, D Qi, Q Zhu, … - Endocrinology, 2008 - Endocrine Soc Pancreatic-derived factor (PANDER) is a cytokine-like peptide highly expressed
in pancreatic β-cells. PANDER was reported to promote apoptosis of pancreatic
β-cells and secrete in response to glucose. Here we explored the effects ... Cited by 4 - Related articles - BL Direct - All 4 versions
J Yang, Z Gao, CE Robert, BR Burkhardt, H … - Biochemistry, 2005 - pubs.acs.org PANDER (pancreatic derived factor, FAM3B) is a novel cytokine, present in
insulin secretory granules, that induces apoptosis of α and β cells of mouse,
rat, and human islets in a dose- and time-dependent manner, and may be ... Cited by 10 - Related articles - All 3 versions
D Jia, M Taguchi, M Otsuki - Metabolism, 2005 - Elsevier Camostat-fed rats gained less weight or lost weight, although they consumed more
food than the control rat when food intake was adjusted for body weight.
Camostat reduced visceral adipose depots and fasting serum concentrations ... Cited by 9 - Related articles - All 13 versions
- ►nih.gov BR Burkhardt, JR Cook, RA Young, BA Wolf - BBA-Gene Regulatory Mechanisms, 2008 - Elsevier Pancreatic Derived Factor (PANDER) is a novel cytokine-like protein dominantly
expressed within the endocrine pancreas. Our previous study demonstrated that
the PANDER promoter was both tissue-specific and glucose-responsive. ... Cited by 2 - Related articles - All 3 versions
Y Zhu, G Xu, A Patel, MM McLaughlin, C … - Genomics, 2002 - Elsevier We report the identification and characterization of a novel cytokine-like gene
family using structure-based methods to search for novel four-helix-bundle
cytokines in genomics databases. There are four genes in this family, ... Cited by 32 - Related articles - BL Direct - All 5 versions
