NJ Spencer-Jones, X Wang, H Snieder, TD Spector, … - Diabetes, 2005 - Am Diabetes Assoc Protein tyrosine phosphatase-1B negatively regulates leptin and insulin signaling, potentially
contributing to hormonal resistance. We selected six tagging single nucleotide polymorphisms
(SNPs) representing 18 common variants in the protein tyrosine phosphatase-1B gene ( ... Cited by 18 - Related articles - BL Direct - All 4 versions
JC Florez, CM Agapakis, NP Burtt, M Sun, P Almgren, L … - Diabetes, 2005 - Am Diabetes Assoc Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 gene, inactivates the insulin
signal transduction cascade by dephosphorylating phosphotyrosine residues in insulin signaling
molecules. Due to its chromosomal location under a chromosome 20 linkage peak and ... Cited by 25 - Related articles - All 8 versions
ND Palmer, JL Bento, JC Mychaleckyj, CD … - DIABETES-NEW …, 2004 - Am Diabetes Assoc Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 gene, catalyzes the dephosphorylation
of pro- teins at tyrosyl residues. PTP-1B has been implicated in negatively regulating insulin
signaling by dephosphory- lating the phosphotyrosine residues of the insulin re- ceptor. ... Cited by 45 - Related articles - BL Direct - All 6 versions
O Ukkola, T Rankinen, T Lakka, AS Leon, JS … - Obesity research, 2005 - ncbi.nlm.nih.gov Protein tyrosine phosphatase 1B (PTPN1) affects the regulation of insulin signaling and energy
metabolism. We studied whether polymorphisms in the PTPN1 gene impact body fat distribution
in the HERITAGE Family Study cohort in 502 white and 276 black subjects. Insulin ... Cited by 9 - Related articles - All 3 versions
NJ Spencer-Jones, X Wang, H Snieder, TD Spector, … - DIABETES, 2005 - Am Diabetes Assoc Page 1. Original Article Protein Tyrosine Phosphatase-1B Gene PTPN1 Selection of
Tagging Single Nucleotide Polymorphisms and Association With Body Fat, Insulin
Sensitivity, and the Metabolic Syndrome in a Normal Female Population ... Related articles - All 13 versions
I Dahlman, H Wahrenberg, L Persson, P Arner - Journal of internal medicine, 2004 - cat.inist.fr No association of reported functional protein tyrosine phosphatase 1 B 3' UTR gene
polymorphism with features of the metabolic syndrome in a Swedish population. I
DAHLMAN, H WAHRENBERG, L PERSSON, P ARNER Journal ... Cited by 10 - Related articles - BL Direct - All 3 versions
JL Bento, ND Palmer, JC Mychaleckyj, LA Lange, CD … - Diabetes, 2004 - Am Diabetes Assoc The PTPN1 gene codes for protein tyrosine phosphatase 1B (PTP1B) (EC 3.1.3.48), which negatively
regulates insulin signaling by dephosphorylating the phosphotyrosine residues of the insulin
receptor kinase activation segment. PTPN1 is located in 20q13, a genomic region linked ... Cited by 69 - Related articles - BL Direct - All 6 versions
S Kipfer-Coudreau, D Eberle, M Sahbatou, A … - Diabetologia, 2004 - Springer Aims/hypothesis. The development of insulin resis- tance may contribute to the occurrence and
progres- sion of the metabolic syndrome associated with obesi- ty. Components contributing
to the insulin pathway and its regulation are good candidates for the molecu- lar study of ... Cited by 11 - Related articles - BL Direct - All 4 versions
M Olivier, CA Hsiung, LM Chuang, LT Ho, CT Ting, … - Hum Mol Genet, 2004 - Oxford Univ Press Page 1. HMG-2004W-00280 Revision 1 S INGLE N UCLEOTIDE P OLYMORPHISMS
IN P ROTEIN T YROSINE P HOSPHATASE 1β (PTPN1) ARE A SSOCIATED WITH
E SSENTIAL H YPERTENSION AND O BESITY Michael ... Cited by 20 - Related articles - BL Direct - All 14 versions
