KG Ewens, RA George, K Sharma, FN … - Diabetes, 2005 - Am Diabetes Assoc Several lines of evidence, including familial aggregation, suggest that allelic
variation contributes to risk of diabetic nephropathy. To assess the evidence
for specific susceptibility genes, we used the transmission/disequilibrium ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org AJ McKnight, AP Maxwell, S Sawcer, A … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol In an effort to accelerate the identification of susceptibility genes in
diabetic nephropathy, the first genome-wide fluorescence-based DNA
microsatellite (n = 6000) association screen was performed, using pools of ... Cited by 19 - Related articles - BL Direct - All 5 versions
JD Center, AS Krolewski… - Kidney international, 2006 - mhp.koshigaya.saitama.jp Nominal P-values foe evidence for linkage in all relatives on 22 q, 5q and 7q
were lower than empirical, indicating that the nominal P-values may have
slightly overstated the evidence for linkage to these regions. In contrast, ... Cited by 42 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org BI Freedman, PJ Hicks, MM Sale, ED Pierson … - Nephrology Dialysis Transplantation, 2007 - ERA-EDTA Background. Four linkage analyses have identified a region on chromosome
18q22-23 that appears to harbour a diabetic nephropathy (DN) susceptibility
locus. A trinucleotide repeat sequence in exon 2 of the carnosinase gene ... Cited by 32 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org A Shimazaki, Y Kawamura, A Kanazawa, A … - Diabetes, 2005 - Am Diabetes Assoc To search for a gene(s) conferring susceptibility to diabetic nephropathy (DN),
we genotyped over 80,000 gene-based single nucleotide polymorphisms (SNPs) in
Japanese patients and identified that the engulfment and cell motility 1 ... Cited by 45 - Related articles - All 7 versions
I Vardarli, LJ Baier, RL Hanson, I Akkoyun, … - Kidney international, 2002 - nature.com Diabetic nephropathy is the major cause of end-stage renal failure in patients
with diabetes mellitus types 1 and 2. Epidemiological studies have suggested a
genetic susceptibility to diabetic nephropathy. The aim of this study was ... Cited by 91 - Related articles - BL Direct - All 5 versions
RL Hanson, DW Craig, MP Millis, KA Yeatts, … - Diabetes, 2007 - Am Diabetes Assoc To identify genetic variants contributing to end-stage renal disease (ESRD) in
type 2 diabetes, we performed a genome-wide analysis of 115,352 single
nucleotide polymorphisms (SNPs) in pools of 105 unrelated case subjects ... Cited by 24 - Related articles - BL Direct - All 5 versions
AM Osterholm, B He, J Pitkaniemi, L Albinsson … - Kidney International, 2006 - nature.com Diabetic nephropathy (DN) is the primary cause of morbidity and mortality in
patients with type 1 as well as type 2 diabetes, and accounts for 40% of
end-stage renal disease in the Western world. Familial clustering of DN ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org B Janssen, D Hohenadel, P Brinkkoetter, V … - Diabetes, 2005 - Am Diabetes Assoc The risk of diabetic nephropathy is partially genetically determined. Diabetic
nephropathy is linked to a gene locus on chromosome 18q22.3-q23. We aimed to
identify the causative gene on chromosome 18 and to study the mechanism by ... Cited by 80 - Related articles - BL Direct - All 8 versions
SK Iyengar, HE Abboud, KAB Goddard, MF Saad … - Diabetes, 2007 - Am Diabetes Assoc The Family Investigation of Nephropathy and Diabetes (FIND) was initiated to map
genes underlying susceptibility to diabetic nephropathy. A total of 11 centers
participated under a single collection protocol to recruit large numbers of ... Cited by 37 - Related articles - BL Direct - All 8 versions
