- ►diabetesjournals.org NM Morton, V Densmore, M Wamil, L Ramage, … - Diabetes, 2005 - Am Diabetes Assoc Despite major advances in understanding monogenic causes of morbid obesity, the
complex genetic and environmental etiology of idiopathic metabolic syndrome
remains poorly understood. One hypothesis suggests that similarities ... Cited by 19 - Related articles - BL Direct - All 6 versions
JH Goedecke, DJ Wake, NS Levitt, EV … - CLINICAL ENDOCRINOLOGY-OXFORD-, 2006 - interscience.wiley.com Objective Glucocorticoid hyperactivity in adipose tissue, due to up-regulation
of local glucocorticoid reactivation by 11β-hydroxysteroid dehydrogenase-1
(11HSD1) or of glucocorticoid receptors (GR), may underpin susceptibility ... Cited by 16 - Related articles - BL Direct - All 5 versions
[CITATION] Omental fat 11beta-HSD1, but not GR, is correlated with fat cell size independently of obesity'in …
- ►angrylapdog.com GR Small, PWF Hadoke, I Sharif, AR Dover, … - Proceedings of the National Academy of Sciences, 2005 - National Acad Sciences Angiogenesis restores blood flow to healing tissues, a process that is inhibited
by high doses of glucocorticoids. However, the role of endogenous
glucocorticoids and the potential for antiglucocorticoid therapy to enhance ... Cited by 26 - Related articles - BL Direct - All 10 versions
[CITATION] beta-hydroxysteroid dehydrogenase type 1 induction in the arcuate nucleus by high-fat …
- ►endojournals.org JM Paterson, MC Holmes, CJ Kenyon, R Carter … - Endocrinology, 2007 - Endocrine Soc 11ß-Hydroxysteroid dehydrogenase type 1 (11ß-HSD1) acts as a reductase in
vivo, regenerating active glucocorticoids within cells from circulating inert
11-keto forms, thus amplifying local glucocorticoid action. 11ß-HSD1 is ... Cited by 7 - Related articles - BL Direct - All 4 versions
SJY Wang, S Birtles, J De Schoolmeester, J … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 1333–1337 DOI 10.1007/s00125-006-0239-y SHORT
COMMUNICATION SJY Wang . S. Birtles . J. de Schoolmeester . J. Swales . ... Cited by 16 - Related articles - BL Direct - All 4 versions
- ►endojournals.org NM Morton, L Ramage, JR Seckl - Endocrinology, 2004 - Endocrine Soc The enzyme 11ß-hydroxysteroid dehydrogenase type 1 (11ß-HSD-1) amplifies
intracellular glucocorticoid action in vivo. 11ß-HSD-1 activity is increased in
adipose tissues of obese humans and genetically obese rodents, providing a ... Cited by 45 - Related articles - BL Direct - All 5 versions
P Alberts, Y Rönquist-Nii, C Larsson, G … - Hormone and metabolic research. Hormon-und …, 2005 - ncbi.nlm.nih.gov The present study was performed to compare glucocorticoid levels in obese KKA
(y) and ob/ob mice with those in normal C57BL/6J mice, and the effect of
high-fat diet on glucocorticoids in KKA (y) and ob/ob mice. Liver, ... Cited by 17 - Related articles - BL Direct - All 3 versions
[CITATION] beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of …
