- ►shouxi.net D Bruder, AM Westendorf, W Hansen, S … - Diabetes, 2005 - Am Diabetes Assoc Targeting of antigens to immature dendritic cells has been shown to result in
antigen-specific T-cell tolerance in vivo. In the INS-HA/TCR-HA transgenic mouse
model for type 1 diabetes, we tested the potential of the dendritic cell– ... Cited by 33 - Related articles - BL Direct - All 7 versions
- ►hematologylibrary.org I Caminschi, AI Proietto, F Ahmet, S … - Blood, 2008 - bloodjournal.hematologylibrary.org A novel dendritic cell (DC)–restricted molecule, Clec9A, was identified by
gene expression profiling of mouse DC subtypes. Based on sequence similarity, a
human ortholog was identified. Clec9A encodes a type II membrane protein ... Cited by 15 - Related articles - All 5 versions
- ►aacrjournals.org K Mahnke, Y Qian, S Fondel, J Brueck, C … - Cancer Research, 2005 - AACR Anti ( )-DEC-205 antibodies target to the DEC-205 receptor that mediates antigen
presentation to T cells by dendritic cells. To exploit these properties for
immunization purposes, we conjugated the melanoma antigen ... Cited by 35 - Related articles - BL Direct - All 4 versions
D Sancho, D Mourão-Sá, OP Joffre, O Schulz … - The Journal of clinical investigation, 2008 - pubmedcentral.nih.gov The mouse CD8α + DC subset excels at cross-presentation of antigen, which can
elicit robust CTL responses. A receptor allowing specific antigen targeting to
this subset and its equivalent in humans would therefore be useful for the ... Cited by 20 - Related articles - BL Direct - All 22 versions
- ►jimmunol.org E Tagliani, P Guermonprez, J Sepulveda, M … - The Journal of Immunology, 2008 - Am Assoc Immnol Improvement of the strategy to target tumor Ags to dendritic cells (DCs) for
immunotherapy requires the identification of the most appropriate
ligand/receptor pairing. We screened a library of Ab fragments on mouse DCs ... Cited by 7 - Related articles - All 5 versions
- ►nih.gov A Mukhopadhaya, T Hanafusa, I Jarchum, YG … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Type 1 diabetes (T1D) is an autoimmune disease resulting from defects in central
and peripheral tolerance and characterized by T cell-mediated destruction of
islet β cells. Cytotoxic CD8 + T cells, reactive to β cell antigens, are ... Cited by 8 - Related articles - BL Direct - All 7 versions
- ►nih.gov C Huysamen, JA Willment, KM Dennehy, GD … - Journal of Biological Chemistry, 2008 - ASBMB We describe here the first characterization of CLEC9A, a group V C-type
lectin-like receptor located in the “Dectin-1 cluster” of related receptors,
which are encoded within the natural killer (NK)-gene complex. Expression ... Cited by 13 - Related articles - All 8 versions
FVV Castro, AL Tutt, AL White, JL Teeling, S … - European Journal of Immunology, 2008 - interscience.wiley.com The magnitude and quality of T cell responses generated when Ag is targeted to
receptors on DC is influenced by both the specific receptor targeted and its
distribution among DC subsets. Here we examine the targeting of the model ... Cited by 14 - Related articles - All 3 versions
L Chatenoud, 2000 - content.karger.com Type 1 diabetes mellitus (T1D) is a T-cell-mediated autoimmune disease [1, 2].
It is thus logical to modulate the immune system to stop the progression of the
disease as it is widely done for other autoimmune diseases. T1D presents, ... Cited by 3 - Related articles - All 4 versions
