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Scholar Results 1 - 10 of about 101 related to Brodnicki: Localization of Idd11 is not associated with thymus and NKT cell abnormalities.... (0.12 sec) 

Localization of Idd11 is not associated with thymus and NKT cell abnormalities in …


TC Brodnicki, AL Fletcher, DG Pellicci, SP Berzins, P … - Diabetes, 2005 - Am Diabetes Assoc
Congenic mouse strains provide a unique resource for genetic dissection and biological characterization
of chromosomal regions associated with diabetes progression in the nonobese diabetic
(NOD) mouse. Idd11, a mouse diabetes susceptibility locus, was previously localized to a ...
Cited by 4 - Related articles - BL Direct - All 6 versions

Through regulation of TCR expression levels, an Idd7 region gene (s) interactively …

- jimmunol.org
DV Serreze, CM Choisy-Rossi, AE Grier, TM … - The Journal of …, 2008 - Am Assoc Immnol
When expressed in NOD, but not C57BL/6 (B6) genetic background mice, the common class
I variants encoded by the H2 g7 MHC haplotype aberrantly lose the ability to mediate the thymic
deletion of autoreactive CD8 + T cells contributing to type 1 diabetes (T1D). This indicated ...
Cited by 3 - Related articles - All 2 versions

Subcongenic analysis of genetic basis for impaired development of invariant NKT …


YG Chen, JP Driver, PA Silveira, DV Serreze - Immunogenetics, 2007 - Springer
Abstract Reduced numbers and function of invariant NKT (iNKT) cells partially contribute to type
1 diabetes (T1D) development in NOD mice. Previous linkage analysis identified a genetic locus
on chromosome 2 controlling numbers of thymic iNKT cells. Interestingly, this locus ...
Cited by 8 - Related articles - BL Direct - All 3 versions

“Agouti NOD”: identification of a CBA-derived Idd locus on Chromosome 7 and its …


J Chen, PC Reifsnyder, F Scheuplein, WH Schott, M … - Mammalian Genome, 2005 - Springer
Page 1. ''Agouti NOD'': identification of a CBA-derived Idd locus on Chromosome
7 and its use for chimera production with NOD embryonic stem cells Jing Chen, 1
Peter C. Reifsnyder, 1 Felix Scheuplein, 2 William H. Schott, 1 ...
Cited by 6 - Related articles - BL Direct - All 4 versions

Dysregulation of T Cell Peripheral Tolerance in Type 1 Diabetes


R Tisch, B Wang - Advances in Immunology, 2008 - Elsevier
The hallmark of a functional immune system is the capacity to distinguish between foreign antigens
expressed by pathogens, and self antigens expressed by the body. The lack of a pathological
response to self-antigens is dependent on a number of events that occur centrally and ...
Cited by 1 - Related articles - All 3 versions

Defect in TCR-CD3ζ signaling mediates T cell hypo-responsiveness in mesenteric …


HJ Yi, CG Lee, HK Kwon, JS So, A Sahoo, JS Hwang, … - Molecular immunology, 2008 - Elsevier
Mesenteric lymph node (MLN) in gut-associated lymphoid tissue plays obligatory roles in the
induction of oral tolerance and ignorance to commensals. However, little is known about its immunological
characteristics. In this study, we investigated the hypo-responsiveness of MLN CD4 + T ...
Cited by 1 - Related articles - All 4 versions

[CITATION] The murine type 1 diabetes loci


CJ Lord, S Howlett, PA Lyons, LB Peterson, LS Wicker, … - Idd1, Idd3, Idd5, Idd9, 2001
Cited by 7 - Related articles

Identification of the transcription factor ARNTL2 as a candidate gene for the type 1 …

- oxfordjournals.org
MS Hung, P Avner, UC Rogner - Human Molecular Genetics, 2006 - Oxford Univ Press
The Idd6 murine type 1 diabetes locus has been shown to control diabetes by regulating the
protective activity of the peripheral immune system, as demonstrated by diabetes transfer assays
using splenocytes. The analysis of three novel subcongenic (NOD.C3H nonobese. C3H) ...
Cited by 8 - Related articles - BL Direct - All 6 versions

Fine-Mapping of the Mouse T Lymphocyte Fraction (Tlf) Locus on Chromosome 9: …


RB Pearce - Autoimmunity, 1998 - informahealthcare.com
T/f (T lymphocyte fraction) defines a locus that governs the unusually high fraction of circulating
T lymphocytes in the nonobese diabetic (NOD) mouse. We previously mapped T/f to proximal
Chromosome 9 in BCI mice.l'l Here, Tlf was tine-mapped on Chromosonie 9 using 8 ...
Cited by 2 - Related articles - BL Direct - All 5 versions

Gene-gene interactions in the NOD mouse model of type 1 diabetes


WM Ridgway, LB Peterson, JA Todd, DB Rainbow, B … - Advances in Immunology, 2008 - Elsevier
Human genome wide association studies (GWAS) have recently identified at least four new,
non-MHC-linked candidate genes or gene regions causing type one diabetes (T1D), highlighting
the need for functional models to investigate how susceptibility alleles at multiple ...
Cited by 2 - Related articles - All 3 versions


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