TC Brodnicki, AL Fletcher, DG Pellicci, SP Berzins, P … - Diabetes, 2005 - Am Diabetes Assoc Congenic mouse strains provide a unique resource for genetic dissection and biological characterization
of chromosomal regions associated with diabetes progression in the nonobese diabetic
(NOD) mouse. Idd11, a mouse diabetes susceptibility locus, was previously localized to a ... Cited by 4 - Related articles - BL Direct - All 6 versions
- ►jimmunol.org DV Serreze, CM Choisy-Rossi, AE Grier, TM … - The Journal of …, 2008 - Am Assoc Immnol When expressed in NOD, but not C57BL/6 (B6) genetic background mice, the common class
I variants encoded by the H2 g7 MHC haplotype aberrantly lose the ability to mediate the thymic
deletion of autoreactive CD8 + T cells contributing to type 1 diabetes (T1D). This indicated ... Cited by 3 - Related articles - All 2 versions
YG Chen, JP Driver, PA Silveira, DV Serreze - Immunogenetics, 2007 - Springer Abstract Reduced numbers and function of invariant NKT (iNKT) cells partially contribute to type
1 diabetes (T1D) development in NOD mice. Previous linkage analysis identified a genetic locus
on chromosome 2 controlling numbers of thymic iNKT cells. Interestingly, this locus ... Cited by 8 - Related articles - BL Direct - All 3 versions
J Chen, PC Reifsnyder, F Scheuplein, WH Schott, M … - Mammalian Genome, 2005 - Springer Page 1. ''Agouti NOD'': identification of a CBA-derived Idd locus on Chromosome
7 and its use for chimera production with NOD embryonic stem cells Jing Chen, 1
Peter C. Reifsnyder, 1 Felix Scheuplein, 2 William H. Schott, 1 ... Cited by 6 - Related articles - BL Direct - All 4 versions
R Tisch, B Wang - Advances in Immunology, 2008 - Elsevier The hallmark of a functional immune system is the capacity to distinguish between foreign antigens
expressed by pathogens, and self antigens expressed by the body. The lack of a pathological
response to self-antigens is dependent on a number of events that occur centrally and ... Cited by 1 - Related articles - All 3 versions
HJ Yi, CG Lee, HK Kwon, JS So, A Sahoo, JS Hwang, … - Molecular immunology, 2008 - Elsevier Mesenteric lymph node (MLN) in gut-associated lymphoid tissue plays obligatory roles in the
induction of oral tolerance and ignorance to commensals. However, little is known about its immunological
characteristics. In this study, we investigated the hypo-responsiveness of MLN CD4 + T ... Cited by 1 - Related articles - All 4 versions
[CITATION] The murine type 1 diabetes loci
CJ Lord, S Howlett, PA Lyons, LB Peterson, LS Wicker, … - Idd1, Idd3, Idd5, Idd9, 2001 Cited by 7 - Related articles
- ►oxfordjournals.org MS Hung, P Avner, UC Rogner - Human Molecular Genetics, 2006 - Oxford Univ Press The Idd6 murine type 1 diabetes locus has been shown to control diabetes by regulating the
protective activity of the peripheral immune system, as demonstrated by diabetes transfer assays
using splenocytes. The analysis of three novel subcongenic (NOD.C3H nonobese. C3H) ... Cited by 8 - Related articles - BL Direct - All 6 versions
RB Pearce - Autoimmunity, 1998 - informahealthcare.com T/f (T lymphocyte fraction) defines a locus that governs the unusually high fraction of circulating
T lymphocytes in the nonobese diabetic (NOD) mouse. We previously mapped T/f to proximal
Chromosome 9 in BCI mice.l'l Here, Tlf was tine-mapped on Chromosonie 9 using 8 ... Cited by 2 - Related articles - BL Direct - All 5 versions
WM Ridgway, LB Peterson, JA Todd, DB Rainbow, B … - Advances in Immunology, 2008 - Elsevier Human genome wide association studies (GWAS) have recently identified at least four new,
non-MHC-linked candidate genes or gene regions causing type one diabetes (T1D), highlighting
the need for functional models to investigate how susceptibility alleles at multiple ... Cited by 2 - Related articles - All 3 versions