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Scholar Results 1 - 10 of about 101 related to Haugaard: Skeletal muscle insulin signaling defects downstream of PI3K at the level of Akt.... (0.10 sec) 

Skeletal muscle insulin signaling defects downstream of PI3K at the level of Akt are …

- diabetesjournals.org
SB Haugaard, O Andersen, S Madsbad, C Frøsig, J … - Diabetes, 2005 - Am Diabetes Assoc
More than 40% of HIV-infected patients on highly active antiretroviral therapy (HAART) experience
fat redistribution (lipodystrophy), a syndrome associated with insulin resistance primarily affecting
insulin-stimulated nonoxidative glucose metabolism (NOGM ins ). Skeletal muscle ...
Related articles

Skeletal muscle insulin signaling defects downstream of phosphatidylinositol 3- …


SB Haugaard, O Andersen, S Madsbad, C Frøsig, J … - Diabetes, 2005 - Am Diabetes Assoc
More than 40% of HIV-infected patients on highly active antiretroviral therapy (HAART) experience
fat redistribution (lipodystrophy), a syndrome associated with insulin resistance primarily affecting
insulin-stimulated nonoxidative glucose metabolism (NOGM ins ). Skeletal muscle ...
Cited by 11 - Related articles - BL Direct - All 5 versions

Therapeutic dose of HIV-1 protease inhibitor saquinavir does not permanently …


P Algenstaedt, S Daneshi, B Schwarzloh, N … - Experimental and …, 2003 - thieme-connect.com
The introduction of HIV-1 protease inhibitor therapy has significantly improved the expectancy
and quality of life for HIV-infected patients. Recent reports have highlighted the development
of metabolic complications in patients taking protease inhibitors, including abnormalities ...
Cited by 4 - Related articles - BL Direct - All 5 versions

Adverse effects of antiretroviral therapy for HIV infection: a review of selected topics


D Nolan, P Reiss, S Mallal - eds, 2005 - Informa Pharma Science
In the current era of HIV treatment, the toxicity profiles of antiretroviral drugs have increasingly
emerged as a basis for selecting initial antiretroviral regimens as well as a reason for switching
therapy in treatment-experienced patients. In this respect, an intensive research effort ...
Cited by 14 - Related articles - All 4 versions

Defective glucose and lipid metabolism in human immunodeficiency virus-infected …

- eje-online.org
SB Haugaard, O Andersen, F Dela, JJ Holst, H … - European Journal of …, 2005 - EFES
Results: Compared with NONLIPO and NAÏVE separately, LIPO displayed markedly reduced
ratio of limb to trunk fat (RLF; >34%, P < 0.001), hepatic insulin sensitivity (>40%, P < 0.03), incremental
glucose disposal (>50%, P < 0.001) and incremental exogenous glucose storage (>50%, ...
Cited by 28 - Related articles - All 8 versions

Hyperproinsulinaemia in normoglycaemic lipodystrophic HIV-infected patients.


SB Haugaard, O Andersen, CN Hales, I … - European journal of …, 2006 - pt.wkhealth.com
Results: LIPO exhibited increased fasting IP and SP (P < 0·05), a higher proportion of elevated
fasting IP (3·1 pmol L -1 , 66% vs. 33% and 28%, P < 0·05) and SP (7·2 pmol L -1 , 50%, 11%
and 0%, P < 0·01), reduced Si RD (> 50%, P < 0·001) and increased ISR (P < 0·001) ...
Cited by 3 - Related articles - BL Direct - All 6 versions

The effects of protease inhibitors on basal and insulin-stimulated lipid metabolism, …

- jlr.org
C Cammalleri, RJ Germinario - The Journal of Lipid Research, 2003 - ASBMB
The objective of our research was to investigate the effects of the protease inhibitors
ritonavir, saquinavir, and indinavir on triglyceride synthesis, lipolysis, insulin binding, and signaling
in differentiating 3T3 L1 pre-adipocytes. Saquinavir, ritonavir, and indinavir all stimulated ...
Cited by 17 - Related articles - All 4 versions

Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal …


K Højlund, P Stæhr, BF Hansen, KA Green, DG Hardie, … - Diabetes, 2003 - Am Diabetes Assoc
In type 2 diabetes, insulin activation of muscle glycogen synthase (GS) is impaired. This defect
plays a major role for the development of insulin resistance and hyperglycemia. In animal
muscle, insulin activates GS by reducing phosphorylation at both NH 2 - and ...
Cited by 59 - Related articles - BL Direct - All 4 versions

[beta]-Cell dysfunction and low insulin clearance in insulin-resistant human …


SB Haugaard, O Andersen, A Volund, BR … - Clinical …, 2005 - pt.wkhealth.com
Results: β-Cell secretory capacity (ie the rate of change in insulin secretion per unit change in
glucose concentration) was similar in lipodystrophic and nonlipodystrophic patients (6·2 ± 1·0
mU kg -1 min -1 mg -1 dl vs. 5·4 ± 0·4, P > 0·4), but insulin sensitivity was reduced by 61% ...
Cited by 11 - Related articles - BL Direct - All 8 versions

Phosphorylation-dependent translocation of glycogen synthase to a novel structure …

- jbc.org
C Prats, JA Cadefau, R Cussó, K Qvortrup, JN … - Journal of Biological …, 2005 - ASBMB
Glycogen metabolism has been the subject of extensive research, but the mechanisms by which
it is regulated are still not fully understood. It is well accepted that the rate-limiting enzymes in
glycogenesis and glycogenolysis are glycogen synthase (GS) and glycogen ...
Cited by 19 - Related articles - All 8 versions


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