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Scholar Results 1 - 10 of about 101 related to Murray: Plasma free fatty acids and peroxisome proliferator–activated receptor α in the.... (0.09 sec) 

Plasma free fatty acids and peroxisome proliferator–activated receptor α in the control of …


AJ Murray, M Panagia, D Hauton, GF Gibbons, … - Diabetes, 2005 - Am Diabetes Assoc
Diabetic patients have abnormal cardiac energy metabolism associated with high
plasma free fatty acid (FFA) concentrations. We investigated whether high plasma
FFAs increase mitochondrial uncoupling protein (UCP) levels in the mouse ...
Cited by 53 - Related articles - BL Direct - All 5 versions

Plasma Free Fatty Acids and Peroxisome ProliferatoreCActivated Receptor in the Control of …


AJ Murray, M Panagia, D Hauton, GF Gibbons, … - 糖尿病学杂志, 2005 - journal.shouxi.net
Diabetic patients have abnormal cardiac energy metabolism associated with high
plasma free fatty acid (FFA) concentrations. We investigated whether high plasma
FFAs increase mitochondrial uncoupling protein (UCP) levels in the mouse ...
Related articles - Cached

Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice

- shouxi.net
OJ How, E Aasum, DL Severson, WY Chan, … - Diabetes, 2006 - Am Diabetes Assoc
Altered cardiac metabolism and function (diabetic cardiomyopathy) has been
observed in diabetes. We hypothesize that cardiac efficiency, the ratio of
cardiac work (pressure-volume area [PVA]) and myocardial oxygen consumption ...
Cited by 58 - Related articles - BL Direct - All 5 versions

Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair …

- ahajournals.org
S Boudina, S Sena, BT O'Neill, P Tathireddy, … - Circulation, 2005 - Am Heart Assoc
Methods and Results— Cardiac function, M O 2 , mitochondrial respiration, and
ATP synthesis were measured in 9-week-old ob/ob and control mouse hearts.
Contractile function and M O 2 in glucose-perfused ob/ob hearts were ...
Cited by 75 - Related articles - All 10 versions

Mitochondrial uncoupling: a key contributor to reduced cardiac efficiency in diabetes

- physiology.org
S Boudina, ED Abel - Physiology, 2006 - Am Physiological Soc
Diabetes is a worldwide epidemic (112). Cardiovascular disease remains the major
cause of morbidity and mortality in people with diabetes. Epidemiological
studies suggest that the prevalence of heart failure exceeds that which can ...
Cited by 39 - Related articles - BL Direct - All 5 versions

Reduced cardiac efficiency and altered substrate metabolism precedes the onset of …

- endojournals.org
J Buchanan, PK Mazumder, P Hu, G … - Endocrinology, 2005 - Endocrine Soc
Hyperglycemia is associated with altered myocardial substrate use, a condition
that has been hypothesized to contribute to impaired cardiac performance. The
goals of this study were to determine whether changes in cardiac ...
Cited by 69 - Related articles - BL Direct - All 5 versions

Hypoxia-induced decrease of UCP3 gene expression in rat heart parallels metabolic gene …


MF Essop, P Razeghi, C McLeod, ME Young, … - Biochemical and Biophysical Research …, 2004 - Elsevier
Mitochondrial uncoupling proteins 2 and 3 (UCP2 and UCP3) are postulated to
contribute to antioxidant defense, nutrient partitioning, and energy efficiency
in the heart. To distinguish isotype function in response to metabolic ...
Cited by 22 - Related articles - All 4 versions

Mechanisms responsible for enhanced fatty acid utilization by perfused hearts from type 2 …


AN Carley, LL Atkinson, A Bonen, ME Harper … - Archives of physiology and biochemistry, 2007 - informahealthcare.com
The aim of this study was to determine the biochemical mechanism(s) responsible
for enhanced FA utilization (oxidation and esterification) by perfused hearts
from type 2 diabetic db/db mice. The plasma membrane content of fatty acid ...
Cited by 14 - Related articles - BL Direct - All 6 versions

Uncoupling protein 3 transcription is regulated by peroxisome proliferator-activated receptor …

- fasebj.org
ME YOUNG, S PATIL, JUN Ying, C DEPRE, … - The FASEB Journal, 2001 - FASEB
Relatively little is known concerning the regulation of uncoupling proteins
(UCPs) in the heart. We investigated in the adult rodent heart 1) whether
changes in workload, substrate supply, or cytokine (TNF- ) administration ...
Cited by 141 - Related articles - BL Direct - All 3 versions

Uncoupling proteins in human heart


AJ Murray, RE Anderson, GC Watson, GK … - The Lancet, 2004 - Elsevier
Abnormal energetic activity in heart failure correlates inversely with plasma
free-fatty-acid concentrations. However, the link between energetic and
metabolic abnormalities is unknown. To investigate this association, we ...
Cited by 104 - Related articles - All 11 versions


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