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Scholar Results 1 - 10 of about 101 related to Nakano: A functional variant in the human betacellulin gene promoter is associated with type.... (0.12 sec) 

A functional variant in the human betacellulin gene promoter is associated with type 2 …

- diabetesjournals.org
Y Nakano, H Furuta, A Doi, S Matsuno, T … - Diabetes, 2005 - Am Diabetes Assoc
Betacellulin (BTC) plays an important role in differentiation, growth, and
antiapoptosis of pancreatic β-cells. We characterized about 2.3 kb of the
5′-flanking region of human BTC gene and identified six polymorphisms (− ...
Cited by 1 - Related articles - BL Direct - All 5 versions

Molecular scanning of the betacellulin gene for mutations in type 2 diabetic patients


T Nakagawa, H Furuta, T Sanke, S … - Diabetes research and clinical practice, 2005 - Elsevier
Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, is an
important factor in the growth and/or differentiation of pancreatic β cells. In
this point of view, we determined the transcriptional start site of the ...
Cited by 5 - Related articles - All 10 versions

Genetic contributions to Type 2 diabetes: recent insights


MM Sale, SS Rich - Expert Review of Molecular Diagnostics, 2007 - ingentaconnect.com
10.1586/14737159.7.2.207 © 2007 Future Drugs Ltd ISSN 1473-7159 207 ...
Michèle M Sale and Stephen S Rich † ... † Author for correspondence
University of Virginia, Center for Public Health Genomics, Charlottesville, ...
Cited by 4 - Related articles - BL Direct - All 4 versions

Bile salt-stimulated lipase (BSSL) distribution in rat, mouse and transgenic mouse …


N Poorkhalkali, AS Lidmer, LG Lundberg, MA … - Histochemistry and cell biology, 1998 - Springer
&p.1:Abstract In some species, including man and mouse, bile salt-stimulated
lipase (BSSL) in milk catalyzes the hydrolysis of triacylglycerides into
glycerol and free fat- ty acids, a reaction that is of particular ...
Cited by 4 - Related articles - BL Direct - All 3 versions

C-peptide response to glucagon in type 2 diabetes mellitus: a comparison with oral glucose …


Y Iwasaki, K Kondo, H Hasegawa, Y Oiso - Diabetes research (Edinburgh, Scotland), 1994 - ncbi.nlm.nih.gov
1: Diabetes Res. 1994;25(3):129-37. C-peptide response to glucagon in type 2 diabetes
mellitus: a comparison with oral glucose tolerance test. ...
Cited by 4 - Related articles - BL Direct - All 2 versions

Structural Insights into the Design of Nonpeptidic Isothiazolidinone-containing Inhibitors of …

- jbc.org
PJ Ala, L Gonneville, M Hillman, M Becker- … - Journal of Biological Chemistry, 2006 - ASBMB
Structural analyses of the protein-tyrosine phosphatase 1B (PTP1B) active site
and inhibitor complexes have aided in optimization of a peptide inhibitor
containing the novel (S)-isothiazolidinone (IZD) phosphonate mimetic. ...
Cited by 5 - Related articles - All 6 versions

The exon 1 Cys7Gly polymorphism within the betacellulin gene is associated with type 2 …

- diabetesjournals.org
K Silver, M Tolea, J Wang, TI Pollin, F Yao, BD … - Diabetes, 2005 - Am Diabetes Assoc
In vitro and in vivo studies suggest a role for betacellulin in islet neogenesis
and regeneration. Since abnormalities in β-cell function play a role in the
development of type 2 diabetes, a mutation in the betacellulin gene could ...
Cited by 14 - Related articles - All 5 versions

Role of μ-opioid receptors in insulin release in the presence of inhibitory and excitatory …


MJ Garcı́a-Barrado, MC Iglesias-Osma, R … - European journal of pharmacology, 2002 - Elsevier
In mouse pancreatic islets incubated under static conditions, the inhibitory
effects on glucose-evoked insulin release induced by adrenaline (1 μM),
clonidine (2 μM) and UK 14,304 (brimonidine, 0.001–1 μM) were abolished ...
Cited by 6 - Related articles - All 4 versions

Is exenatide a useful addition to diabetes therapy?


NE Mikhail - Endocrine Practice, 2006 - AACE
Defective insulin secretion and insulin resistance con- tribute independently to
the development of type 2 dia- betes (1). In addition, type 2 diabetes is
generally charac- terized by inappropriately elevated plasma fasting and ...
Cited by 6 - Related articles - BL Direct - All 2 versions

Localization of opioid receptor antagonist [3H]-LY255582 binding sites in mouse brain: …

- u-bordeaux2.fr [PDF] 
SL Gackenheimer, TM Suter, JE Pintar, SJ … - Neuropeptides, 2005 - Elsevier
Agonist stimulation of opioid receptors increases feeding in rodents, while
opioid antagonists inhibit food intake. The pan-opioid antagonist, LY255582,
produces a sustained reduction in food intake and body weight in rodent ...
Cited by 6 - Related articles - All 8 versions


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