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Scholar Results 1 - 10 of about 101 related to Micallef: Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells. (0.12 sec) 

Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells

- diabetesjournals.org [PDF] 
SJ Micallef, ME Janes, K Knezevic, RP Davis, … - Diabetes, 2005 - Am Diabetes Assoc
CD4 + CD25 + T-cells can be used to interfere with spon- taneous autoimmune
diseases such as type 1 diabetes. However, their low frequency and often unknown
spec- ificity represent major obstacles to their therapeutic use. Here we ...
Cited by 53 - Related articles - All 5 versions

Inducing embryonic stem cells to differentiate into pancreatic {beta} cells by a novel three- …

- alphamedpress.org
Y Shi, L Hou, F Tang, W Jiang, P Wang, M … - Stem Cells, 2005 - AlphaMed Press
Experimental induction of embryonic stem cells (ESCs) to become pancreatic ß
cells can potentially provide ample resource for cell transplantation therapy of
type I diabetes mellitus. Most of the previously reported induction ...
Cited by 96 - Related articles - All 6 versions

Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes


E Jaeckel, H von Boehmer, MP Manns - Diabetes, 2005 - Am Diabetes Assoc
CD4 + CD25 + T-cells can be used to interfere with spontaneous autoimmune
diseases such as type 1 diabetes. However, their low frequency and often unknown
specificity represent major obstacles to their therapeutic use. Here we ...
Cited by 124 - Related articles - All 5 versions

Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells …

- diabetesjournals.org
S Miyazaki, E Yamato, J Miyazaki - Diabetes, 2004 - Am Diabetes Assoc
Embryonic stem (ES) cells can differentiate into many cell types. Recent reports
have shown that ES cells can differentiate into insulin-producing cells.
However, the differentiation is not efficient enough to produce insulin- ...
Cited by 155 - Related articles - BL Direct - All 4 versions

[PDF] Embryonic stem cells differentiate into insulin-producing cells without selection of nestin- …


P Blyszczuk, C Asbrand, A Rozzo, G Kania, … - Int J Dev Biol, 2004 - ijdb.ehu.es
ABSTRACT We present a new strategy for the differentiation of embryonic stem
(ES) cells into insulin-producing cells via a multi-step process without
selection and induction of nestin-positive cells. During ES cell ...
Cited by 66 - Related articles - View as HTML - All 6 versions

[PDF] The generation of insulin-producing cells from embryonic stem cells—a discussion of …


G Kania, P Blyszczuk, AM Wobus - Int J Dev Biol, 2004 - ijdb.ehu.es
ABSTRACT The derivation of insulin-producing cells from embryonic stem (ES)
cells has been controversially described. Whereas several authors showed
successful differentiation of mouse ES cells into islet-like clusters, ...
Cited by 35 - Related articles - View as HTML - All 7 versions

Artifactual insulin release from differentiated embryonic stem cells


M Hansson, A Tonning, U Frandsen, A Petri, J … - Diabetes, 2004 - Am Diabetes Assoc
Several recent reports claim the generation of insulin-producing cells from
embryonic stem cells via the differentiation of progenitors that express nestin.
Here, we investigate further the properties of these insulin-containing ...
Cited by 139 - Related articles - BL Direct - All 4 versions

Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells


BW Kahan, LM Jacobson, DA Hullett, JM … - Diabetes, 2003 - Am Diabetes Assoc
Embryonic stem (ES) cells differentiating in vitro reproduce many facets of
early embryonic development, including the expression of developmentally
regulated transcription factors and the differentiation of multipotent ...
Cited by 101 - Related articles - BL Direct - All 6 versions

TGF-{beta} signaling potentiates differentiation of embryonic stem cells to Pdx-1 expressing …


N Shiraki, CJ Lai, Y Hishikari, S Kume - Genes to Cells, 2005 - Mol Biology Soc Japan
Embryonic stem (ES) cells have the capacity to differentiate to every cell type
that constitutes fetal or adult tissues. To trace and quantitatively assess the
differentiation of ES cells into gut endodermal cells, we used an ES cell ...
Cited by 16 - Related articles - All 5 versions

Insulin expressing cells from differentiated embryonic stem cells are not beta cells


S Sipione, A Eshpeter, JG Lyon, GS Korbutt, … - Diabetologia, 2004 - Springer
Aim/hypothesis. Embryonic stem (ES) cells have been proposed as a potential
source of tissue for transplan- tation for the treatment of Type 1 diabetes.
However, studies showing differentiation of beta cells from ES cells are ...
Cited by 123 - Related articles - BL Direct - All 6 versions


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