- ►shouxi.net E Jaeckel, H von Boehmer, MP Manns - Diabetes, 2005 - Am Diabetes Assoc CD4 + CD25 + T-cells can be used to interfere with spontaneous autoimmune
diseases such as type 1 diabetes. However, their low frequency and often unknown
specificity represent major obstacles to their therapeutic use. Here we ... Cited by 124 - Related articles - All 5 versions
- ►diabetesjournals.org [PDF] SJ Micallef, ME Janes, K Knezevic, RP Davis, … - Diabetes, 2005 - Am Diabetes Assoc CD4 + CD25 + T-cells can be used to interfere with spon- taneous autoimmune
diseases such as type 1 diabetes. However, their low frequency and often unknown
spec- ificity represent major obstacles to their therapeutic use. Here we ... Cited by 53 - Related articles - All 5 versions
- ►jimmunol.org EL Masteller, MR Warner, Q Tang, KV Tarbell, … - The Journal of Immunology, 2005 - Am Assoc Immnol CD4 + CD25 + Foxp3 + regulatory T cells (T reg ) are critical for controlling
autoimmunity. Evidence suggests that T reg development, peripheral maintenance,
and suppressive function are dependent on Ag specificity. However, there is ... Cited by 105 - Related articles - BL Direct - All 4 versions
- ►rupress.org Q Tang, KJ Henriksen, M Bi, EB Finger, G Szot … - Journal of Experimental Medicine, 2004 - jem.rupress.org The low number of CD4 + CD25 + regulatory T cells (T regs ), their anergic
phenotype, and diverse antigen specificity present major challenges to
harnessing this potent tolerogenic population to treat autoimmunity and ... Cited by 446 - Related articles - BL Direct - All 11 versions
KV Tarbell, S Yamazaki, K Olson, P Toy, RM … - Journal of Experimental Medicine, 2004 - jem.rupress.org In the nonobese diabetic (NOD) mouse model of type 1 diabetes, the immune system
recognizes many autoantigens expressed in pancreatic islet ß cells. To silence
autoimmunity, we used dendritic cells (DCs) from NOD mice to expand CD25 + ... Cited by 348 - Related articles - BL Direct - All 9 versions
K Loser, W Hansen, J Apelt, S Balkow, J Buer, … - Gene therapy, 2005 - nature.com Regulatory T cells are promising candidates for the modulation of inflammation
and autoimmunity. To generate regulatory T cells in vitro, we have infected
naïve CD4 + CD25 - T cells with a retrovirus encoding the transcription ... Cited by 51 - Related articles - BL Direct - All 4 versions
JG Chai, S Xue, D Coe, C Addey, I Bartok, D … - Transplantation, 2005 - journals.lww.com Skip Navigation Links Home > May 27, 2005 - Volume 79 - Issue 10 > Regulatory T
Cells, Derived from Naive CD4+CD25- T Cells by... ... 1 Transplantation Biology
Group, Medical Research Council Clinical Sciences Centre, Faculty of ... Cited by 68 - Related articles - BL Direct - All 2 versions
- ►rupress.org SM Pop, CP Wong, DA Culton, SH Clarke, R … - Journal of Experimental Medicine, 2005 - jem.rupress.org Natural CD4 + CD25 + regulatory T (CD4 + CD25 + T reg) cells play a key role in
the immunoregulation of autoimmunity. However, little is known about the
interactions between CD4 + CD25 + T reg cells and autoreactive T cells. ... Cited by 110 - Related articles - All 8 versions
- ►jimmunol.org S Gregori, N Giarratana, S Smiroldo, L Adorini - The Journal of Immunology, 2003 - Am Assoc Immnol In the nonobese diabetic (NOD) mouse, pathogenic and suppressor CD4 + T cells
can be distinguished by the constitutive expression of CD25. In this study, we
demonstrate that the progression of autoimmune diabetes in NOD mice ... Cited by 125 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org N Sarween, A Chodos, C Raykundalia, M … - The Journal of Immunology, 2004 - Am Assoc Immnol It is well established that CD4 + CD25 + regulatory T cells (Tregs) inhibit
autoimmune pathology. However, precisely how the behavior of disease-inducing T
cells is altered by Tregs remains unclear. In this study we use a TCR ... Cited by 80 - Related articles - BL Direct - All 5 versions
