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Redox Paradox


BJ Goldstein, K Mahadev, X Wu - Diabetes, 2005 - Am Diabetes Assoc
Propelled by the identification of a small family of NADPH oxidase (Nox) enzyme
homologs that produce superoxide in response to cellular stimulation with
various growth factors, renewed interest has been generated in ...
Cited by 90 - Related articles - All 6 versions

[PDF] Perspectives in Diabetes


R Paradox - Diabetes, 2005 - Am Diabetes Assoc
Insulin Action Is Facilitated by Insulin-Stimulated ... Reactive Oxygen Species
With Multiple Potential Signaling ... Barry J. Goldstein, Kalyankar Mahadev,
and Xiangdong Wu ... Propelled by the identification of a small family of ...
Related articles

Insulin-Stimulated Reactive Oxygen Species and Insulin Signal Transduction


BJ Goldstein, K Mahadev, X Wu - Oxidative stress and inflammatory mechanisms in …, 2007 - books.google.com
11 Insulin-Stimulated Reactive Oxygen Species and Insulin Signal Transduction
Barry J. Goldstein, Kalyankar Mahadev, and Xiangdong Wu CONTENTS Introduction
178 Regulation of Reversible Tyrosine Phosphorylation in Insulin Signaling ...
Related articles - BL Direct

Role of insulin-induced reactive oxygen species in the insulin signaling pathway

- nih.gov
BJ Goldstein, K Mahadev, X Wu, L Zhu, H … - Antioxidants & redox signaling, 2005 - liebertonline.com
A LTHOUGH HIGH LEVELS of circulating reactive oxygen species have been well
documented to play an impor- tant role in the pathogenesis of tissue damage in
the compli- cations of diabetes mellitus (9), senescence (23), and other ...
Cited by 50 - Related articles - BL Direct - All 4 versions

Regulation of insulin signaling through reversible oxidation of the protein-tyrosine …


TC Meng, DA Buckley, S Galic, T Tiganis, NK … - Journal of Biological Chemistry, 2004 - ASBMB
Many studies have illustrated that the production of reactive oxygen species
(ROS) is important for optimal tyrosine phosphorylation and signaling in
response to diverse stimuli. Protein-tyrosine phosphatases (PTPs), which ...
Cited by 102 - Related articles - BL Direct - All 4 versions

The NAD (P) H oxidase homolog Nox 4 modulates insulin-stimulated generation of H 2 O …


K MAHADEV, H MOTOSHIMA, X WU, JM … - Molecular and cellular biology(Print), 2004 - cat.inist.fr
Insulin stimulation of target cells elicits a burst of H 2 O 2  that
enhances tyrosine phosphorylation of the insulin receptor and its cellular
substrate proteins as well as distal signaling events in the insulin action ...
Cited by 68 - Related articles

The NAD (P) H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and …

- nih.gov
K Mahadev, H Motoshima, X Wu, JM Ruddy, RS … - Molecular and cellular biology, 2004 - Am Soc Microbiol
Insulin stimulation of target cells elicits a burst of H 2 O 2 that enhances
tyrosine phosphorylation of the insulin receptor and its cellular substrate
proteins as well as distal signaling events in the insulin action cascade. ...
Cited by 142 - Related articles - BL Direct - All 6 versions

Hydrogen Peroxide Generated during Cellular Insulin Stimulation Is Integral to Activation of …


K Mahadev, X Wu, A Zilbering, L Zhu, JTR … - Journal of Biological Chemistry, 2001 - ASBMB
In a variety of cell types, insulin stimulation elicits the rapid production of
H 2 O 2 , which causes the oxidative inhibition of protein-tyrosine phosphatases
and enhances the tyrosine phosphorylation of proteins in the early insulin ...
Cited by 131 - Related articles - BL Direct - All 4 versions

The major target of the endogenously generated reactive oxygen species in response to …

- molbiolcell.org
JH Seo, Y Ahn, SR Lee, CY Yeo, KC Hur - Molecular biology of the cell, 2005 - Am Soc Cell Biol
Phosphoinositide-3 kinase (PI-3 kinase) and its downstream signaling molecules
PDK-1 and Akt were analyzed in SK-N-SH and SK-N-BE(2) human neuroblastoma cell
lines. When cells were stimulated with insulin, PI-3 kinase was activated ...
Cited by 59 - Related articles - All 7 versions

[PDF] The NAD (P) H oxidase homolog Nox4 modulates insulin-stimulated generation of H202 and …


K Mahadev, H Motoshima, X Wu, JM Ruddy, RS … - MOLECULAR AND CELLULAR BIOLOGY, 2004 - jdc.jefferson.edu
∗Thomas Jefferson University †Thomas Jefferson University ‡Thomas
Jefferson University ∗∗Thomas Jefferson University ††Emory University
‡‡Emory University §Emory University ¶Thomas Jefferson University, ...
Cited by 1 - Related articles


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