- ►diabetesjournals.org Y Ishigaki, H Katagiri, T Yamada, T Ogihara, J Imai, K … - Diabetes, 2005 - Am Diabetes Assoc For examining whether dissipating excess energy in the liver is a possible therapeutic approach
to high-fat diet–induced metabolic disorders, uncoupling protein-1 (UCP1) was expressed in
murine liver using adenoviral vectors in mice with high-fat diet–induced diabetes and ... Cited by 41 - Related articles - All 5 versions
Y Ishigaki, H Katagiri, T Yamada, T Ogihara, J Imai, K … - Diabetes, 2005 - Am Diabetes Assoc Page 1. Perspectives in Diabetes Dissipating Excess Energy Stored in the Liver Is a Potential
Treatment Strategy for Diabetes Associated With Obesity Yasushi Ishigaki, 1 Hideki Katagiri,
2 Tetsuya Yamada, 1 Takehide Ogihara, 2 Junta Imai, 1,2 Kenji Uno, 1,2 ... Related articles - All 2 versions
T Yamada, H Katagiri, Y Ishigaki, T Ogihara, J Imai, K … - Cell Metabolism, 2006 - Elsevier Intra-abdominal fat accumulation is involved in development of the metabolic syndrome, which
is associated with insulin and leptin resistance. We show here that ectopic expression of very
low levels of uncoupling protein 1 (UCP1) in epididymal fat (Epi) reverses both insulin ... Cited by 40 - Related articles - All 8 versions
K Uno, H Katagiri, T Yamada, Y Ishigaki, T Ogihara, J … - Science, 2006 - sciencemag.org Coordinated control of energy metabolism and glucose homeostasis requires communication
between organs and tissues. We identified a neuronal pathway that participates in the cross
talk between the liver and adipose tissue. By studying a mouse model, we showed that ... Cited by 60 - Related articles - BL Direct - All 7 versions
J Imai, H Katagiri, T Yamada, Y Ishigaki, T Ogihara, K … - Obesity, 2006 - nature.com Formerly known as Obesity Research, Obesity is the official journal of The Obesity Society.
Available in print and online, Obesity is dedicated to increasing knowledge, fostering research,
and promoting better treatment for people with obesity and their loved ones. Obesity publishes ... Cited by 21 - Related articles - All 3 versions
J Gao, H Katagiri, Y Ishigaki, T Yamada, T Ogihara, J … - Diabetes, 2007 - Am Diabetes Assoc Although apolipoprotein E (apoE) is well known to play a major role in lipid metabolism, its role
in glucose and energy homeostasis remains unclear. Herein, we established apoE-deficient
genetically obese Ay (apoE −/− ;Ay/+) mice. ApoE deficiency in Ay mice prevented the ... Cited by 26 - Related articles - BL Direct - All 4 versions
D Langin - Drugs Today, 2003 - journals.prous.com Uncoupling proteins (UCP) are carriers expressed in the mitochondrial inner membrane that
uncouple oxygen consumption by the respiratory chain from ATP synthesis. UCP2 is a member
of the multigenic UCP family that is expressed in a wide range of tissues and organs. ... Cited by 11 - Related articles - All 5 versions
- ►ahajournals.org H Katagiri, T Yamada, Y Oka - Circulation research, 2007 - Am Heart Assoc Obesity, a major healthcare issue, is associated with significant cardiovascular morbidities, including
hypertension and atherosclerosis. Numerous intensive studies conducted this decade have revealed
that adipose tissue is a major endocrine organ that secretes a variety of bioactive ... Cited by 52 - Related articles - All 6 versions
C Son, K Hosoda, K Ishihara, L Bevilacqua, H … - Diabetologia, 2004 - Springer Aims/hypothesis. It has been suggested that uncou- pling protein 3 (UCP3) can increase energy
expendi- ture, thereby regulating body weight. Although stud- ies on UCP3 knock-out mice suggest
that lack of UCP3 function does not cause obesity or Type 2 dia- betes, it is possible that ... Cited by 22 - Related articles - BL Direct - All 4 versions
[CITATION] S.(2002) Type of dietary fat and insulin resistance
