- ►diabetesjournals.org Y Li, X Cao, LX Li, PL Brubaker, H Edlund, DJ … - Diabetes, 2005 - Am Diabetes Assoc Glucagon-like peptide-1 (GLP-1) regulates energy intake, gastrointestinal
motility, and nutrient disposal. The relative importance of the islet β-cell
for GLP-1 actions remains unclear. We determined the role of the islet ... Cited by 71 - Related articles - All 6 versions
BR Gedulin, P Smith, KS Prickett, M Tryon, S … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 1380–1385 DOI 10.1007/s00125-005-1795-2 SHORT
COMMUNICATION BR Gedulin . P. Smith . KS Prickett . M. Tryon . S. Barnhill . ... Cited by 39 - Related articles - BL Direct - All 4 versions
S Park, X Dong, TL Fisher, S Dunn, AK Omer, … - Journal of Biological Chemistry, 2006 - ASBMB The insulin receptor substrate 2 (Irs2) branch of the insulin/insulin-like
growth factor-signaling cascade prevents diabetes in mice because it promotes β
cell replication, function, and survival, especially during metabolic ... Cited by 65 - Related articles - BL Direct - All 8 versions
H Wang, M Iezzi, S Theander, PA Antinozzi, … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Mutations in genes encoding HNF-4α, HNF-1α and
IPF-1/Pdx-1 are associated with, re- spectively, MODY subtypes-1, -3 and -4.
Impaired glucose- stimulated insulin secretion is the common primary defect ... Cited by 29 - Related articles - All 3 versions
- ►diabetesjournals.org LL Baggio, Q Huang, TJ Brown, DJ Drucker - Diabetes, 2004 - Am Diabetes Assoc Peptide hormones exert unique actions via specific G protein–coupled
receptors; however, the therapeutic potential of regulatory peptides is
frequently compromised by rapid enzymatic inactivation and clearance from ... Cited by 94 - Related articles - BL Direct - All 11 versions
- ►endojournals.org H Hui, A Nourparvar, X Zhao, R Perfetti - Endocrinology, 2003 - Endocrine Soc The activation of the glucagon-like peptide-1 (GLP-1) receptor has been shown to
have an important role in the functional activity of islet ß-cells and in the
expansion of the islet cell mass. Constant remodeling of islet cell mass is ... Cited by 141 - Related articles - BL Direct - All 4 versions
J Buteau, ML Spatz, D Accili - Diabetes, 2006 - Am Diabetes Assoc The glucoincretin hormone glucagon-like peptide-1 (GLP-1) increases pancreatic
β-cell proliferation and survival through sequential activation of the
epidermal growth factor receptor (EGFR), phosphatidylinositol-3 kinase (PI ... Cited by 47 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org J Buteau, S Foisy, E Joly, M Prentki - Diabetes, 2003 - Am Diabetes Assoc We previously provided evidence that glucagon-like peptide 1 (GLP-1) induces
pancreatic ß-cell growth nonadditively with glucose in a phosphatidylinositol
(PI) 3-kinase- and protein kinase C -dependent manner. However, the exact ... Cited by 147 - Related articles - BL Direct - All 5 versions
Y Li, T Hansotia, B Yusta, F Ris, PA Halban, … - Journal of Biological Chemistry, 2003 - ASBMB Glucagon-like peptide-1 (GLP-1) stimulates insulin secretion and augments β
cell mass via activation of β cell proliferation and islet neogenesis. We
examined whether GLP-1 receptor signaling modifies the cellular ... Cited by 252 - Related articles - BL Direct - All 7 versions
- ►endocrinology-journals.org BN Friedrichsen, N Neubauer, YC Lee, VK … - Journal of Endocrinology, 2006 - Soc Endocrinology The incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent
insulinotropic peptide (GIP), have been suggested to act as ß-cell growth
factors and may therefore be of critical importance for the maintenance of ... Cited by 33 - Related articles - BL Direct - All 4 versions