MN Weedon, TM Frayling, B Shields, B Knight, … - Diabetes, 2005 - Am Diabetes Assoc Rare mutations in the glucokinase (GCK) gene cause fasting hyperglycemia and
considerably influence birth weight when present in a mother or her offspring.
The role of common variation of GCK is uncertain. A polymorphism at ... Cited by 58 - Related articles - All 13 versions
- ►nih.gov MN Weedon, VJ Clark, Y Qian, Y Ben-Shlomo, N … - The American Journal of Human Genetics, 2006 - Elsevier Fasting glucose is associated with future risk of type 2 diabetes and ischemic
heart disease and is tightly regulated despite considerable variation in
quantity, type, and timing of food intake. In pregnancy, maternal fasting ... Cited by 35 - Related articles - BL Direct - All 13 versions
CS Rose, J Ek, SA Urhammer, C Glumer, K … - Diabetes, 2005 - Am Diabetes Assoc A graded relationship has been reported between fasting and postprandial plasma
glucose levels and the subsequent risk of cardiovascular morbidity and
mortality. We hypoth- esized that the GCK 30G>A promoter polymorphism is ... Cited by 23 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org W Winckler, NP Burtt, J Holmkvist, C Cervin, … - Diabetes, 2005 - Am Diabetes Assoc It is currently unclear how often genes that are mutated to cause rare,
early-onset monogenic forms of disease also harbor common variants that
contribute to the more typical polygenic form of each disease. The gene for ... Cited by 46 - Related articles - BL Direct - All 6 versions
MN Weedon, KR Owen, B Shields, G Hitman, M … - Diabetes, 2005 - Am Diabetes Assoc HNF1α (TCF1) is a key transcription factor that is essential for pancreatic
β-cell development and function. Rare mutations of HNF1α cause maturity-onset
diabetes of the young. A common variant, G319S, private to the Oji-Cree ... Cited by 38 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org W Marz, M Nauck, MM Hoffmann, D Nagel, … - Circulation, 2004 - Am Heart Assoc From the Clinical Institute of Medical and Chemical Laboratory Diagnostics,
Medical University of Graz, Graz, Austria (WM); Division of Clinical Chemistry,
Department of Medicine, University Hospital, Freiburg, Germany (MN, MMH); ... Cited by 27 - Related articles - All 8 versions
M Ounsted, A Scott, VA Moar - Annals of human biology, 1988 - informahealthcare.com Summary. Data are presented on the birthweights of 1092 siblings and 5207
maternal and paternal relatives of 986 probands. Previous analyses had
demonstrated the potency of a maternal regulator constraining fetal growth. ... Cited by 29 - Related articles - All 7 versions
AJ Bennett, U Sovio, A Ruokonen, H … - Diabetes, 2004 - Am Diabetes Assoc Page 1. Brief Genetics Report Variation at the Insulin Gene VNTR (Variable
Number Tandem Repeat) Polymorphism and Early Growth Studies ... Cited by 35 - Related articles - BL Direct - All 4 versions
LM Stone, SE Kahn, WY Fujimoto, SS Deeb, D … - Diabetes, 1996 - Am Diabetes Assoc We sought to determine whether a G -> A variant at position -30 of the beta-cell
promoter of the glucokinase (GCK) gene observed to be present more frequently in
Japanese-American men with impaired glucose tolerance (IGT) than in ... Cited by 36 - Related articles - All 4 versions
- ►diabetesjournals.org TM Frayling, AT Hattersley, A McCarthy, J … - Diabetes, 2002 - Am Diabetes Assoc IGF-I has a critical role in growth and metabolism. A microsatellite
polymorphism 1 kb upstream to the IGF-I gene has recently been associated with
several adult phenotypes. In a large Dutch cohort, the absence of the ... Cited by 75 - Related articles - BL Direct - All 6 versions
