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Scholar Results 1 - 10 of about 101 related to Flavell: Peroxisome proliferator-activated receptor α gene variation influences age of onset.... (0.08 sec) 

Peroxisome proliferator-activated receptor α gene variation influences age of onset and …


DM Flavell, H Ireland, JW Stephens, E Hawe, … - Diabetes, 2005 - Am Diabetes Assoc
Dysregulation of fatty acid metabolism is important in the pathogenesis of type
2 diabetes. Peroxisome proliferator-activated receptor (PPAR)α is a master
regulator of fatty acid catabolism, and PPARα activators delay the onset ...
Cited by 41 - Related articles - All 7 versions

Response to micronized fenofibrate treatment is associated with the peroxisome-proliferator …


C Foucher, S Rattier, DM Flavell, PJ Talmud, … - Pharmacogenetics and Genomics, 2004 - journals.lww.com
Objective: The association between polymorphisms in candidate genes related to
lipoprotein metabolism and the reduction in plasma triglyceride (TG) in response
to fenofibrate treatment was evaluated in subjects with type 2 diabetes ...
Cited by 19 - Related articles - All 6 versions

Variation in the PPARα gene is associated with altered function in vitro and plasma lipid …

- pubget.com [PDF] 
DM Flavell, IP Torra, Y Jamshidi, D Evans, … - Diabetologia, 2000 - Springer
Risk of coronary artery disease (CAD) is determined by a combination of genetic
and environmental fac- tors which influence plasma lipid homeostasis, hae-
mostasis and inflammation. Peroxisome proliferator activated receptor alpha ...
Cited by 114 - Related articles - BL Direct - All 4 versions

A polymorphism, L162V, in the peroxisome proliferator-activated receptor alpha (PPARalpha) …


D Evans, J Aberle, D Wendt, A Wolf, U … - Journal of molecular medicine (Berlin, Germany), 2001 - ncbi.nlm.nih.gov
This study examined the effect a polymorphism (L162V) in the gene for peroxisome
proliferator activated receptor (PPAR) alpha in the development of
non-insulin-dependent diabetes mellitus (type 2 DM), obesity and ...
Cited by 44 - Related articles - BL Direct - All 3 versions

Peroxisome Proliferator-Activated Receptor {alpha} Gene Variants Influence Progression of …

- ahajournals.org
DM Flavell, Y Jamshidi, E Hawe, I Pineda … - Circulation, 2002 - Am Heart Assoc
From the Centre for Cardiovascular Genetics, Department of Medicine, Royal Free
and University College of London Medical School, London, UK (DMF, YJ, EH, SEH,
PJT); U.325 INSERM, Département d'Athérosclérose, Institut Pasteur, ...
Cited by 85 - Related articles - All 8 versions

The peroxisome proliferator-activated receptor {alpha} Leu162Val polymorphism influences the …

- ajcn.org
AM Paradis, B Fontaine-Bisson, Y Bosse, J … - American Journal of Clinical Nutrition, 2005 - Am Soc Nutrition
2 Supported in part by Valorisation-Recherche-Québec, the Canada Research Chair
in Nutrition, Functional Food and Cardiovascular Health and the Fonds de la
recherche en santé du Québec (FRSQ). YB is a recipient of a doctoral ...
Cited by 22 - Related articles - All 5 versions

Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma …

- nutrition.org
ES Tai, D Corella, S Demissie, LA Cupples, O … - Journal of Nutrition, 2005 - Am Soc Nutrition
Peroxisome proliferator-activated receptor (PPAR ) is a nuclear transcription
factor regulating multiple genes involved in lipid metabolism. It was shown that
a common leucine to valine (L162V) substitution at the PPAR gene (PPARA) is ...
Cited by 48 - Related articles - All 11 versions

Single Nucleotide Polymorphisms of the Peroxisome Proliferator–Activated Receptor-α …

- diabetesjournals.org
L Andrulionytė, T Kuulasmaa, JL Chiasson, … - Diabetes, 2007 - Am Diabetes Assoc
Peroxisome proliferator–activated receptor (PPAR) α, a transcription factor
of the nuclear receptor superfamily, regulates fatty acid oxidation. We
evaluated the association of single nucleotide polymorphisms (SNPs) of the ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Molecular scanning of the human PPARa gene: association of the L162v mutation with …

- jlr.org
MC Vohl, P Lepage, D Gaudet, CG Brewer, C … - The Journal of Lipid Research, 2000 - ASBMB
Peroxisome proliferator-activated receptor alpha (PPAR ) is a member of the
steroid hormone receptor super family involved in the control of cellular lipid
utilization. This makes PPAR a candidate gene for type 2 diabetes and ...
Cited by 127 - Related articles - BL Direct - All 2 versions

[CITATION] investigators D: Response to micronized fenofibrate treatment is associated with the …


C Foucher, S Rattier, DM Flavell, PJ Talmud, … - Pharmacogenetics, 2004
Cited by 4 - Related articles


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