- ►shouxi.net X Liu, J Wei, DH Peng, MD Layne, SF Yet - Diabetes, 2005 - Am Diabetes Assoc Increased production of reactive oxygen species contributes to the etiology of
diabetes complications. Pathophysiological stimuli that increase oxidative
stress upregulate heme oxygenase (HO)-1, a cytoprotective heme–degrading ... Cited by 44 - Related articles - All 6 versions
S Quan, PM Kaminski, L Yang, T Morita, M … - Biochemical and Biophysical Research …, 2004 - Elsevier Heme oxygenase-1 (HO-1) represents a key defense mechanism against oxidative
injury. Hyperglycemia has been linked to increased oxidative stress, leading to
endothelial dysfunction, delayed cell replication, and enhanced apoptosis. ... Cited by 48 - Related articles - All 4 versions
- ►shouxi.net CD Filippo, R Marfella, S Cuzzocrea, E Piegari … - Diabetes, 2005 - Am Diabetes Assoc This study investigated the role of heme oxygenase (HO)-1 in the cardiac tissue
injury of acute ischemia/reperfusion (I/R) in diabetic streptozotocin
(STZ)-induced hyperglycemic rats. The effects of 1) hemin, an inducer of HO ... Cited by 42 - Related articles - All 5 versions
- ►physiology.org NG Abraham, R Rezzani, L Rodella, A Kruger, … - American Journal of Physiology- Heart and Circulatory …, 2004 - Am Physiological Soc Heme oxygenase (HO)-1 represents a key defense mechanism against oxidative
injury. Hyperglycemia produces oxidative stress and various perturbations of
cell physiology. The effect of streptozotocin (STZ)-induced diabetes on ... Cited by 59 - Related articles - All 4 versions
- ►ahajournals.org NG Abraham, T Kushida, J McClung, M Weiss, … - Circulation research, 2003 - Am Heart Assoc Heme oxygenase-1 (HO-1) is a stress protein that has been suggested to
participate in defense mechanisms against agents that may induce oxidative
injury, such as heme and inflammatory molecules. Incubation of endothelial ... Cited by 87 - Related articles - BL Direct - All 6 versions
K Takeda, J Lin, S Okubo, S Akazawa-Kudoh, … - Journal of molecular and cellular cardiology, 2004 - Elsevier Transient glucose deprivation (TGD) has been shown to induce a resistance to a
subsequent ischemia and reperfusion injury in the heart. Induction of
cyclooxygenase-2 (COX-2) and heme oxygenase-1 (HO-1) is known to mediate ... Cited by 15 - Related articles - All 5 versions
- ►physiology.org S Turkseven, A Kruger, CJ Mingone, P … - American Journal of Physiology- Heart and Circulatory …, 2005 - Am Physiological Soc Increased heme oxygenase (HO)-1 activity attenuates endothelial cell apoptosis
and decreases superoxide anion (O 2 – ) formation in experimental diabetes by
unknown mechanisms. We examined the effect of HO-1 protein and HO activity ... Cited by 80 - Related articles - BL Direct - All 4 versions
- ►asnjournals.org AI Goodman, PN Chander, R Rezzani, ML … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol Heme oxygenase-1 (HO-1) and -2 play an important role in cytoprotection and are
physiologic regulators of heme-dependent protein synthesis in renal tissues. The
impact of HO-2 deletion comparing hyperglycemic HO-2 (+/+) mice and HO-2 ... Cited by 20 - Related articles - BL Direct - All 5 versions
