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Scholar Results 1 - 10 of about 101 related to Ader: Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying.... (0.12 sec) 

Metabolic dysregulation with atypical antipsychotics occurs in the absence of …

- diabetesjournals.org
M Ader, SP Kim, KJ Catalano, V Ionut, K Hucking, JM … - Diabetes, 2005 - Am Diabetes Assoc
Atypical antipsychotics have been linked to weight gain, hyperglycemia, and diabetes. We examined
the effects of atypical antipsychotics olanzapine (OLZ) and risperidone (RIS) versus placebo on
adiposity, insulin sensitivity (S I ...
Cited by 64 - Related articles - All 7 versions

Atypical antipsychotics and glucose homeostasis.


RN Bergman, M Ader - The Journal of clinical psychiatry, 2005 - ncbi.nlm.nih.gov
OBJECTIVES: Persistent reports have linked atypical antipsychotics with diabetes, yet causative
mechanisms responsible for this linkage are unclear. Goals of this review are to outline the
pathogenesis of nonimmune diabetes ...
Cited by 82 - Related articles - All 2 versions

Evaluation of insulin sensitivity in healthy volunteers treated with olanzapine, …

- endojournals.org
M Sowell, N Mukhopadhyay, P Cavazzoni, C … - Journal of Clinical …, 2003 - Endocrine Soc
The primary objective of this study was to evaluate insulin sensitivity in healthy subjects treated
with olanzapine or risperidone. Subjects were randomly assigned to single-blind therapy with
olanzapine (10 mg/d), risperidone ...
Cited by 38 - Related articles - BL Direct - All 6 versions

Acute effects of atypical antipsychotics on whole-body insulin resistance in rats: …


KL Houseknecht, AS Robertson, W Zavadoski, … - …, 2006 - nature.com
Although it is generally accepted that atypical antipsychotics differ in their risk for diabetic
side effects, the underlying pharmacological mechanisms are unknown. Studies on the mechanisms of
antipsychotic-induced hyperglycemia ...
Cited by 37 - Related articles - BL Direct - All 6 versions

Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from …

- diabetesjournals.org
DE Johnson, H Yamazaki, KM Ward, AW Schmidt, WS … - Diabetes, 2005 - Am Diabetes Assoc
Treatment with the atypical antipsychotics olanzapine and clozapine has been associated with an
increased risk for deterioration of glucose homeostasis, leading to hyperglycemia, ketoacidosis, and
diabetes, in some cases independent ...
Cited by 31 - Related articles - All 6 versions

Glucose metabolism in patients with schizophrenia treated with atypical …

- miami.edu [PDF] 
DC Henderson, E Cagliero, PM Copeland, CP … - Archives of general …, 2005 - Am Med Assoc
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better. ... Background While the ...
Cited by 160 - Related articles - All 8 versions

Effect of olanzapine on body composition and energy expenditure in adults with …

- psychiatryonline.org
KA Graham, DO Perkins, LJ Edwards, RC … - American Journal of …, 2005 - Am Psychiatric Assoc
OBJECTIVE: Weight gain is a commonly observed adverse effect of atypical antipsychotic medications,
but associated changes in energy balance and body composition are not well defined. The authors
report here the effect of ...
Cited by 65 - Related articles - All 4 versions

Effects of antipsychotics on fat deposition and changes in leptin and insulin levels: …


ZHIJUN ZHANG, ZHIJ YAO, WEN LIU, QUN FANG, … - The British Journal of …, 2004 - RCP
Method Abdominal body fat was determined by magnetic resonance imaging in a group of previously
untreated patients with schizophrenia, before and after 10 weeks' antipsychotic drug treatment. Body
mass and blood concentrations of ...
Cited by 104 - Related articles - BL Direct - All 4 versions

Atypical antipsychotic drugs directly impair insulin action in adipocytes: effects on …


HS Vestri, L Maianu, DR Moellering, WT … - …, 2006 - nature.com
Treatment with second-generation antipsychotics (SGAs) has been associated with weight gain and the
development of diabetes mellitus, although the mechanisms are unknown. We tested the hypothesis that
SGAs exert direct cellular effects ...
Cited by 29 - Related articles - BL Direct - All 5 versions

Hyperglycemic clamp assessment of insulin secretory responses in normal …

- endojournals.org
MO Sowell, N Mukhopadhyay, P Cavazzoni, S … - Journal of Clinical …, 2002 - Endocrine Soc
Weight increased significantly (P < 0.01) in the olanzapine (2.8 ± 1.7 kg) and risperidone (3.1 ±
2.1 kg) treatment groups. An increase ( 25%) in the insulin response to hyperglycemia and a decrease
( 18%) in the insulin sensitivity ...
Cited by 91 - Related articles - BL Direct - All 4 versions


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