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Scholar Results 1 - 10 of about 101 related to Fan: Androgen receptor null male mice develop late-onset obesity caused by decreased energy.... (0.11 sec) 

Androgen receptor null male mice develop late-onset obesity caused by decreased …

- diabetesjournals.org
WQ Fan, T Yanase, M Nomura, T Okabe, K Goto, T … - Diabetes, 2005 - Am Diabetes Assoc
Androgen receptor (AR) null male mice (AR L–/Y ) revealed late-onset obesity, which was confirmed
by computed tomography–based body composition analysis. AR L–/Y mice were euphagic compared
with the wild-type male (AR X/Y ) controls, but they were also less dynamic and ...
Cited by 45 - Related articles - All 5 versions

Late onset of obesity in male androgen receptor-deficient (AR KO) mice


T Sato, T Matsumoto, T Yamada, T Watanabe, H … - … and Biophysical Research …, 2003 - Elsevier
An androgen receptor (AR) null mutant mice line was generated by means of a Cre-lox P
system. The male (AR L−/Y ) (KO) mice exhibited typical features of testicular feminization mutant
(Tfm) disease in external reproductive organs with growth retardation. The growth curve ...
Cited by 58 - Related articles - BL Direct - All 5 versions

Testosterone Inhibits Adipogenic Differentiation in 3T3-L1 Cells: Nuclear …

- endojournals.org
R Singh, JN Artaza, WE Taylor, M Braga, X Yuan, NF … - Endocrinology, 2006 - Endocrine Soc
Testosterone supplementation in men decreases fat mass; however, the mechanisms by which
it inhibits fat mass are unknown. We hypothesized that testosterone inhibits adipogenic differentiation
of preadipocytes by activation of androgen receptor (AR)/ß-catenin interaction and ...
Cited by 69 - Related articles - BL Direct - All 4 versions

Androgens and metabolic syndrome: Lessons from androgen receptor knock out ( …


T Yanase, WQ Fan, K Kyoya, L Min, R Takayanagi, … - Journal of Steroid …, 2008 - Elsevier
Testosterone (T) is an important factor for determining body composition in males. Abdominal
obesity is inversely correlated with serum T levels in men, leading to greater mortality. Pathologically
hypogonadal men also have a significantly higher fat mass, which is reversed by T ...
Cited by 9 - Related articles - All 2 versions

Insulin-like growth factor 1/insulin signaling activates androgen signaling through …

- jbc.org
WQ Fan, T Yanase, H Morinaga, T Okabe, M … - Journal of Biological …, 2007 - ASBMB
The androgen-androgen receptor (AR) system plays vital roles in a wide array of biological
processes, including prostate cancer development and progression. Several growth factors,
such as insulin-like growth factor 1 (IGF1), can induce AR activation, whereas insulin ...
Cited by 20 - Related articles - All 6 versions

Protein kinase A potentiates adrenal 4 binding protein/steroidogenic factor 1 …

- endojournals.org
WQ Fan, T Yanase, Y Wu, H Kawate, M Saitoh, K … - Molecular …, 2004 - Endocrine Soc
The mechanism through which protein kinase A (PKA) potentiates the transactivation ability of
adrenal 4 binding protein/steroidogenic factor 1 (Ad4BP/SF-1) is currently unclear. In the present
study, we investigated the mechanism by applying laser confocal microscopy and ...
Cited by 37 - Related articles - BL Direct - All 3 versions

Nuclear compartmentalization of N-CoR and its interactions with steroid receptors

- nih.gov
Y Wu, H Kawate, K Ohnaka, H Nawata, R … - Molecular and Cellular …, 2006 - Am Soc Microbiol
The repression mechanisms by the nuclear receptor corepressor (N-CoR) of steroid hormone
receptor (SHR)-mediated transactivation were examined. Yellow fluorescent protein
(YFP)-N-CoR was distributed as intranuclear discrete dots, while coexpression of ...
Cited by 13 - Related articles - BL Direct - All 8 versions

Androgen receptor gene repeats and indices of obesity in older adults


DR Gustafson, MJ Wen, BM Koppanati - International journal of obesity, 2003 - nature.com
MEASUREMENTS: Genotyping the GGN and CAG repeats of the AR gene, and measuring body
weight, height and waist and hip circumferences. Waist was measured at the umbilicus
(wstumb), iliac crest (wstili), and mid-way between the iliac crest and lowest rib (wstwst). ...
Cited by 28 - Related articles - BL Direct - All 4 versions

Interrelationships between intraabdominal fat and total serum testosterone levels in …


F Armellini, M Zamboni, S Castelli, R Robbi, A … - Metabolism: clinical …, 1994 - ncbi.nlm.nih.gov
Thirty-six women aged 18 to 52 years with body mass indexes (BMIs) between 27 and 52 were
studied. Visceral and subcutaneous fat areas and body fat were evaluated by computerized tomography
with a single scan at the IV-V lumbar vertebra level. Glucose, insulin, and C-peptide ...
Cited by 15 - Related articles - BL Direct - All 3 versions

Relative impact of androgen and estrogen receptor activation in the effects of …


K Venken, K De Gendt, S Boonen, J … - Journal of Bone and …, 2006 - Am Soc Bone Min Res
Hello. Sign in to personalize your visit. New user? Register now. ... Laboratory for Experimental
Medicine and Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium. ... The authors
state that they have no conflicts of interest. ... The relative importance of AR and ER ...
Cited by 35 - Related articles - BL Direct - All 8 versions


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