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Scholar Results 1 - 10 of about 101 related to Noronha: Inducible nitric oxide synthase has divergent effects on vascular and metabolic.... (0.12 sec) 

Inducible nitric oxide synthase has divergent effects on vascular and metabolic function in …


BT Noronha, JM Li, SB Wheatcroft, AM Shah, … - Diabetes, 2005 - Am Diabetes Assoc
Previous studies have suggested an involvement of inducible nitric oxide
synthase (iNOS) in obesity, but the relation, if any, between this and
mechanisms underlying endothelial dysfunction in obesity is unknown. We ...
Cited by 31 - Related articles - All 5 versions

Preserved glucoregulation but attenuation of the vascular actions of insulin in mice …

- diabetesjournals.org
SB Wheatcroft, AM Shah, JM Li, E Duncan, … - Diabetes, 2004 - Am Diabetes Assoc
Type 2 diabetes is preceded by years of insulin resistance and is characterized
by reduced bioavailability of the antiatherosclerotic signaling molecule nitric
oxide (NO) and premature atherosclerosis. The relationship between ...
Cited by 20 - Related articles - BL Direct - All 5 versions

Vascular endothelial function and blood pressure homeostasis in mice overexpressing IGF …

- diabetesjournals.org
SB Wheatcroft, MT Kearney, AM Shah, DJ … - Diabetes, 2003 - Am Diabetes Assoc
IGFs and their binding proteins (IGFBPs) play a significant role in metabolic
regulation, and there is growing evidence that they also exert important
vascular effects. IGFBP-1 contributes to glucose counterregulation, and ...
Cited by 20 - Related articles - BL Direct - All 9 versions

Application of the nitric oxide donor SNAP to cardiomyocytes in culture provides protection …


E Monastyrskaya, N Folarin, I Malyshev, C … - Nitric Oxide, 2002 - Elsevier
Multiple data indicates that nitric oxide (NO) donors retain immediate
protective effects against different disturbances in cardiovascular system. The
aim of the present study was to investigate delayed effects of nitric oxide ...
Cited by 16 - Related articles - All 3 versions

Marked heterogeneity of endothelin-mediated contractility and contraction dynamics in …

- ebmonline.org
CC Widmer, AL Mundy, M Kretz, M Barton - Experimental Biology and Medicine, 2006 - SEBM
Although endothelin (ET)-1 is one of the strongest known vasoconstrictors in
most species, we and others have previously found that it is only weakly
effective in the mouse aorta. The aim of this study was to further ...
Cited by 9 - Related articles - BL Direct - All 3 versions

Effect of fat distribution on endothelial-dependent and endothelial-independent …


IL Williams, PJ Chowienczyk, SB Wheatcroft, … - Diabetes, obesity & metabolism, 2006 - pt.wkhealth.com
Methods: Seventy-three healthy people (44 women; age range: 24-64 years) with
body mass index (BMI) range of 18.6-73.1 kg/m 2 were recruited. All participants
underwent assessment of conduit artery endothelial-dependent vasodilatation ...
Cited by 23 - Related articles - BL Direct - All 7 versions

A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese …

- diabetesjournals.org
M Fujimoto, N Shimizu, K Kunii, JA Martyn, K … - Diabetes, 2005 - Am Diabetes Assoc
Chronic inflammation has been postulated to play an important role in the
pathogenesis of insulin resistance. Inducible nitric oxide synthase (iNOS) has
been implicated in many human diseases associated with inflammation. iNOS ...
Cited by 24 - Related articles - All 5 versions

Endothelial function and weight loss in obese humans


IL Williams, PJ Chowienczyk, SB Wheatcroft … - Obesity surgery, 2005 - Springer
Background: Obesity is a major risk factor for the development of endothelial
dysfunction. We explored the effect of different degrees of body mass on
endothelial function, lipids, systemic inflammation and glucose homeostasis ...
Cited by 37 - Related articles - BL Direct - All 5 versions

Accelerated endothelial dysfunction in mild prediabetic insulin resistance: the early role of …

- physiology.org
ER Duncan, SJ Walker, VA Ezzat, SB … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
Insulin resistance is well established as an independent risk factor for the
development of type 2 diabetes and cardiovascular atherosclerosis. Most studies
have examined atherogenesis in models of severe insulin resistance or ...
Cited by 13 - Related articles - BL Direct - All 3 versions

Fat intake modifies vascular responsiveness and receptor expression of vasoconstrictors: …

- cardiovascres.org
AL Mundy, E Haas, I Bhattacharya, CC Widmer … - Cardiovascular research, 2007 - cardiovascres.org
Methods: C57BL/6 mice were fed diets of normal (Control, 12.3% kcal from fat),
high (HF, 41% kcal from fat) and very high (VHF, 58% kcal from fat) fat content
for 15 weeks. Glucose tolerance tests were performed, and aortic rings were ...
Cited by 17 - Related articles - All 10 versions


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