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Scholar Results 1 - 10 of about 101 related to Williams: Loss of Heparan N-Sulfotransferase in Diabetic Liver. (0.11 sec) 

Loss of Heparan N-Sulfotransferase in Diabetic Liver

- diabetesjournals.org
KJ Williams, ML Liu, Y Zhu, X Xu, WR Davidson, P … - Diabetes, 2005 - Am Diabetes Assoc
The basis for accelerated atherosclerosis in diabetes is unclear. Diabetes is associated with
loss of heparan sulfate (HS) from the liver, which may impede lipoprotein clearance and thereby
worsen atherosclerosis. To study hepatic HS loss in diabetes, we examined regulation of ...
Cited by 19 - Related articles - All 5 versions

Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich …

- nih.gov
JM MacArthur, JR Bishop, KI Stanford, L … - Journal of Clinical …, 2007 - Am Soc Clin Investig
We examined the role of hepatic heparan sulfate in triglyceride-rich lipoprotein metabolism by
inactivating the biosynthetic gene GlcNAc N-deacetylase/N-sulfotransferase 1 (Ndst1) in hepatocytes
using the Cre-loxP system, which resulted in an approximately 50% reduction in sulfation ...
Cited by 63 - Related articles - BL Direct - All 7 versions

Fatty acids cause alterations of human arterial smooth muscle cell proteoglycans …

- ahajournals.org [PDF] 
M Rodriguez-Lee, G Ostergren-Lunden, B … - … , and vascular biology, 2006 - Am Heart Assoc
Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams & Wilkins, a division
of Wolters ... Fatty Acids Cause Alterations of Human Arterial Smooth
Cited by 16 - Related articles - All 7 versions

Influence of high glucose concentrations on the expression of glycosaminoglycans …

- oxfordjournals.org
B Yard, Y Feng, H Keller, C Mall, F van der … - Nephrology Dialysis …, 2002 - ERA-EDTA
Results. In each group of patients, 25 mM D-glucose significantly reduced the incorporation of
[ 3 H]glucosamine (P<0.01), but not [ 35 S]sulphate. The quantity of NDST 1 mRNA expression
did not differ between the four groups. In the non-diabetic group only, 25 mM D-glucose ...
Cited by 6 - Related articles - BL Direct - All 4 versions

[PDF] Lipoprotein-matrix interactions in macrovascular disease in diabetes


LR Tannock, A Chait - Front Biosci, 2004 - bioscience.org
1. Abstract 2. Introduction 2.1. Response to retention hypothesis 2.2. Composition of vascular
extracellular matrix 3. Lipoprotein Determinants of Retention 3.1. Proteoglycan binding site of
apo B100 3.2. Proteoglycan binding site of apo B48 3.3. Proteoglycan binding site of apo ...
Cited by 17 - Related articles - View as HTML - All 3 versions

Influence of glucose on production and N-sulfation of heparan sulfate in cultured …


N Parthasarathy, LF Gotow, JD Bottoms, JC … - Molecular and Cellular …, 2000 - Springer
Page 1. 1 Molecular and Cellular Biochemistry 213: 1–9, 2000. © 2000 Kluwer
Academic Publishers. Printed in the Netherlands. Influence of glucose on production
and N-sulfation of heparan sulfate in cultured adipocyte cells ...
Cited by 8 - Related articles - BL Direct - All 5 versions

Retention of low-density lipoprotein in atherosclerotic lesions of the mouse: …

- ahajournals.org
M Gustafsson, M Levin, K Skalen, J Perman, V … - Circulation …, 2007 - Am Heart Assoc
Direct binding of apolipoprotein (apo)B-containing lipoproteins to proteoglycans is the initiating
event in atherosclerosis, but the processes involved at later stages of development are
unclear. Here, we investigated the importance of the apoB–proteoglycan interaction in the ...
Cited by 18 - Related articles - All 5 versions

Rapid regression of atherosclerosis: insights from the clinical and experimental …


KJ Williams, JE Feig, EA Fisher - Nature Clinical Practice Cardiovascular …, 2008 - nature.com
KJ Williams is Professor of Medicine, Professor of Biochemistry and Molecular Biology, and a
Member of the Center for Human Virology and Biodefense at Thomas Jefferson University,
Philadelphia, PA, USA. His research on cardiovascular disease focuses on how normal ...
Cited by 20 - Related articles - BL Direct - All 5 versions

Changes in matrix proteoglycans induced by insulin and fatty acids in hepatic cells …


U Olsson, AC Egnell, MR Lee, GÖ Lundén, M … - Diabetes, 2001 - Am Diabetes Assoc
Insulin resistance and type 2 diabetes are associated with elevated circulating levels of
insulin, nonesterified fatty acids (NEFAs), and lipoprotein remnants. Extracellular matrix proteoglycan
(PG) alterations are also common in macro- and microvascular complications of type 2 ...
Cited by 22 - Related articles - BL Direct - All 5 versions

[CITATION] Classic Paper: The birth of proteoglycans: the nature of the link between protein …


TE Hardingham - Biochem J, 2007
Cited by 2 - Related articles


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