N Abate, M Chandalia, P Satija, B Adams-Huet, SM … - Diabetes, 2005 - Am Diabetes Assoc Genetic susceptibility modulates the impact of obesity on risk for type 2 diabetes. The present
study evaluates the role of ENPP1 K121Q polymorphism in prediction of type 2 diabetes in three
populations that differ in ... Cited by 74 - Related articles - All 9 versions
S Bacci, O Ludovico, S Prudente, YY Zhang, R Di … - Diabetes, 2005 - Am Diabetes Assoc Insulin resistance (IR) is pathogenic for type 2 diabetes and coronary artery disease (CAD). The
K121Q polymorphism of the ENPP1/PC-1 gene is associated with IR. Our aim was to investigate the role
of the 121Q variant on the risk of ... Cited by 54 - Related articles - BL Direct - All 5 versions
N Matsuoka, A Patki, HK Tiwari, DB Allison, SB … - International Journal of …, 2005 - nature.com To test for association of the ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) K121Q
polymorphism with body mass index (BMI) and diabetes in a large sample of Caucasians and
African-Americans by selectively ... Cited by 40 - Related articles - BL Direct - All 4 versions
- ►pubget.com [PDF] N Grarup, SA Urhammer, J Ek, A Albrechtsen, C … - Diabetologia, 2006 - Springer Page 1. ARTICLE Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes,
insulin resistance and obesity in 7,333 Danish white subjects N. Grarup & SA Urhammer & J. Ek & A.
Albrechtsen & C. Glümer & K. Borch-Johnsen & T. Jørgensen & T. Hansen & O. Pedersen ... Cited by 41 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org J Bochenski, G Placha, K Wanic, M Malecki, J Sieradzki … - Diabetes, 2006 - Am Diabetes Assoc The K121Q polymorphism in ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is associated
with type 2 diabetes and obesity. The possibility of other ENPP1 polymorphisms influencing these
phenotypes has received little ... Cited by 35 - Related articles - BL Direct - All 6 versions
D Meyre, N Bouatia-Naji, A Tounian, C Samson, … - Nature …, 2005 - pubmedcentral.nih.gov We identified a childhood obesity locus on chromosome 6q16.3-q24.2 1 that includes 2.4 Mb common to
eight genome scans for Type 2 diabetes (T2D) or obesity 1 - 8 . Analysis of the ENPP1 (PC-1) gene, a
candidate for insulin resistance 9 ... Cited by 161 - Related articles - BL Direct - All 10 versions
- ►tokushima-u.ac.jp [PDF] P Keshavarz, H Inoue, Y Sakamoto, K Kunika, T … - Journal of Human …, 2006 - Springer Abstract Ecto-nucleotide pyrophosphatase/phosphodi- esterase 1 (ENPP1, also known as PC-1) inhibits
insulin signal transduction pathway(s). Previous studies have demonstrated the K121Q variant of the
ENPP1 gene to have a significant ... Cited by 29 - Related articles - BL Direct - All 9 versions
- ►endojournals.org N Abate, L Carulli, A Cabo-Chan Jr, M … - Journal of Clinical …, 2003 - Endocrine Soc Genetic susceptibility may be responsible for high prevalence of insulin resistance in Asian
Indians. This study was carried out in samples of local Asian Indians and Caucasians to determine
whether plasma cell membrane ... Cited by 61 - Related articles - BL Direct - All 4 versions
BV Costanzo, V Trischitta, R Di Paola, D Spampinato, A … - Diabetes, 2001 - Am Diabetes Assoc When overexpressed, the membrane glycoprotein PC-1 may play a role in human insulin resistance
through the inhibition of insulin receptor (IR) autophosphorylation. A PC-1 variant (K 121 Q, with
lysine 121 replaced by glutamine) ... Cited by 76 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org HN Lyon, JC Florez, T Bersaglieri, R Saxena, W … - Diabetes, 2006 - Am Diabetes Assoc The common missense single nucleotide polymorphism (SNP) K121Q in the ectoenzyme nucleotide
pyrophosphate phosphodiesterase (ENPP1) gene has recently been associated with type 2 diabetes in
Italian, US, and South-Asian ... Cited by 48 - Related articles - BL Direct - All 7 versions
