- ►shouxi.net KM Gillespie, R Nolsøe, VM Betin, OP … - Diabetes, 2005 - Am Diabetes Assoc The pubertal peak in onset of type 1 diabetes occurs earlier in girls than boys.
We postulated that this sex difference might be mediated in part by estrogen or
by genes regulated by estrogen, such as the interleukin-6 (IL6) gene. ... Cited by 19 - Related articles - All 5 versions
PDF Version - john-libbey-eurotext.fr Summary : Multiple immune mediators have been mentioned as playing a role in the
pathomechanism of type1 DM. Interleukin (IL)-1β, and tumor necrosis factor
(TNF)-α play a central role in the autoimmune destruction of pancreatic β- ... Cited by 6 - Related articles - All 5 versions
MM Jahromi, BA Millward, AG Demaine - Journal of interferon & cytokine research, 2000 - liebertonline.com Page 1. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 20:885–888 (2000) Mary Ann Liebert,
Inc. A Polymorphism in the Promoter Region of the Gene for ... Cited by 76 - Related articles - BL Direct - All 3 versions
- ►oxfordjournals.org OP Kristiansen, RL Nolsoe, L Larsen, AMP … - Human Molecular Genetics, 2003 - Oxford Univ Press The type 1 diabetes mellitus (T1DM) candidate gene SNP IL6-174G/C was genotyped
in 253 Danish T1DM families (1129 individuals). TDT analysis demonstrated
linkage in the presence of association between the IL6-174C allele and T1DM ... Cited by 25 - Related articles - BL Direct - All 4 versions
SJ Privat, A Oo, LD Waterbury - PROCEEDINGS-WESTERN PHARMACOLOGY …, 2001 - unr.edu Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects
systemic joints. Chronic synovitis of- ten leads to irreversible destruction of
periarticular carti- lage and bone. The inflamed synovium is characterized by Cited by 3 - Related articles - View as HTML - BL Direct - All 6 versions
[CITATION] Tejido adiposo: órgano de almacenamiento y secreción
GVZ Dedoussis, Y Manios, DM Choumerianou, … - Obesity research, 2004 - 万方数据资源系统 Interleukin-6 (IL-6) is a pleiotropic cytokine expressed in many tissues. A
polymorphism in the IL-6 gene, associated with differences in IL-6 transcription
rate, has been recently described. Subjects with the -174GG genotype are ... Cited by 11 - Related articles - BL Direct - All 3 versions
P Eerligh, BPC Koeleman, F Dudbridge, GJ … - Genes and Immunity, 2004 - nature.com Genetic association with type 1 diabetes (T1D) has been established for two
chromosomal regions: HLA DQ/DR (IDDM1) and INS VNTR (IDDM2). To identify
additional genetic markers, we tested polymorphisms in regulatory regions ... Cited by 27 - Related articles - BL Direct - All 3 versions
T Illig, F Bongardt, A Schöpfer-Wendels, C … - Gesundheitswesen, 2005 - thieme-connect.com Die KORA-Studien bieten eine hervorragende Basis, um komplexe Erkrankungen wie
Typ-2-Diabetes oder das metabolische Syndrom auf genetischer Ebene zu
analysieren. In diesen Studien wurden mehr als 2000 Typ-2-Diabetiker ... Cited by 12 - Related articles - BL Direct - All 4 versions