PA Tataranni, E Ortega - Diabetes, 2005 - Am Diabetes Assoc There is growing support for the hypothesis that obesity is an inflammatory condition leading
to chronic activation of the innate immune system, which ultimately causes progressive impairment
of glucose tolerance. Experimental studies in animals and evidence from prospective and ... Cited by 103 - Related articles - All 9 versions
AB Question - PAT, 2004 - Am Diabetes Assoc There is growing support for the hypothesis that obesity is an inflammatory condition leading
to chronic activa- tion of the innate immune system, which ultimately causes progressive impairment
of glucose tolerance. Experimental studies in animals and evidence from prospective and ... Related articles
PA Tataranni - Drug Discovery Today: Disease Mechanisms, 2005 - Elsevier There is increasing evidence that subclinical inflammation is a risk factor for insulin
resistance, type 2 diabetes mellitus and cardiovascular disease. Consequently, because the
chain of molecular events linking inflammation to impairment of insulin signaling and ... Cited by 5 - Related articles
BB Duncan, MI Schmidt - Diabetes Technology & Therapeutics, 2006 - liebertonline.com The fattening of the human species and the accompanying emergence of the metabolic syn-
drome and of type 2 diabetes as remarkably frequent clinical entities are among the major
epi- demiologic events of our time. Control of the diabetes epidemic requires a greater ... Cited by 21 - Related articles - BL Direct - All 3 versions
S Liu, L Tinker, Y Song, N Rifai, DE Bonds, … - Archives of Internal …, 2007 - archinte.highwire.org Methods Among 82 069 postmenopausal women aged 50 to 79 years without cardiovascular
disease or diabetes mellitus who participated in the Women's Health Initiative Observational
Study, we prospectively examined the relationships of plasma levels of tumor necrosis ... Cited by 26 - Related articles - BL Direct - All 4 versions
H Chen - Pharmacological research, 2006 - Elsevier Type 2 diabetes is rapidly becoming a worldwide epidemic. Obesity and sedentary lifestyle are
the main environmental causes for the development of insulin resistance and type 2
diabetes. In the past decade, it has been increasingly recognized that obesity and insulin ... Cited by 32 - Related articles - All 4 versions
- ►diabetesjournals.org FB Hu, JB Meigs, TY Li, N Rifai, JAE Manson - Diabetes, 2004 - Am Diabetes Assoc We conducted a prospective, nested, case-control study of inflammatory markers as predictors
of type 2 diabetes among 32,826 women who provided blood samples in 1989 through 1990
in the Nurses' Health Study. Among women free of diabetes, cardiovascular disease, or ... Cited by 235 - Related articles - BL Direct - All 7 versions
JC Pickup - Diabetes care, 2004 - Am Diabetes Assoc There is increasing evidence that an ongoing cytokine-induced acute-phase response (sometimes
called low-grade inflammation, but part of a widespread activation of the innate immune
system) is closely involved in the pathogenesis of type 2 diabetes and associated ... Cited by 365 - Related articles - BL Direct - All 8 versions
- ►ejcpr-selection.com M Pirro, G Schillaci, G Savarese, F Gemelli, … - European Journal of …, 2004 - journals.lww.com Background: Increased arterial stiffness has been found in patients with chronic high-grade inflammatory
diseases. Whether mitigation of low-grade systemic inflammation, through a
low-cholesterol/low-saturated fat diet, may have a role in improving arterial stiffness is still ... Cited by 19 - Related articles - All 11 versions
S Stranges, LB Rafalson, J Dmochowski, K Rejman, … - Obesity, 2008 - nature.com In conditional logistic regression analyses accounting for traditional risk factors (age, family history
of diabetes, smoking, drinking status, and BMI), E-selectin was positively related (3rd vs. 1st
tertile: odds ratio 2.77, 95% confidence interval (CI) 1.13–6.79, P for linear trend = 0.023) ... Related articles - All 3 versions
