- ►diabetesjournals.org J Shao, L Qiao, RC Janssen, M Pagliassotti, … - Diabetes, 2005 - Am Diabetes Assoc Acute hyperglycemia normally suppresses hepatic glucose production (HGP) and
gluconeogenic gene expression. Conversely, chronic hyperglycemia is accompanied
by progressive increases in basal HGP and is a major contributor to ... Cited by 29 - Related articles - All 5 versions
- ►endojournals.org L Qiao, PS MacLean, H You, J Schaack, J … - Endocrinology, 2006 - Endocrine Soc CCAAT/enhancer-binding protein- (C/EBP ) is a member of the basic leucine zipper
transcription factor family and regulates expression of several enzymes in the
liver that control glucose and lipid metabolism. Using ... Cited by 10 - Related articles - BL Direct - All 3 versions
- ►jbc.org RW Hanson - Journal of Biological Chemistry, 2005 - ASBMB I have spent a lifetime in the area of intermediary metabolism and have seen it
move from the center of biochemistry to the backwater of our science in a very
short period, only to be re-discovered by a new generation of biologists. ... Cited by 13 - Related articles - All 4 versions
- ►jbc.org L Qiao, OA MacDougald, J Shao - Journal of Biological Chemistry, 2006 - ASBMB Excessive hepatic gluconeogenesis and glucose production are important
contributors to hyperglycemia in both type 1 and type 2 diabetes. In diabetic
humans and animal models, elevated levels of p38 mitogen-activated protein ... Cited by 14 - Related articles - All 6 versions
- ►endojournals.org K Matsusue, O Gavrilova, G Lambert, HB … - Molecular Endocrinology, 2004 - Endocrine Soc CCAAT/enhancer binding protein (C/EBP ) is a critical factor in glucose
metabolism in the neonate as revealed by conventional C/EBP -null mice that do
not survive beyond the first day after birth because of severe hypoglycemia ... Cited by 16 - Related articles - BL Direct - All 3 versions
T Luedde, M Duderstadt, KL Streetz, F Tacke … - Hepatology, 2004 - interscience.wiley.com The CCAAT enhancer-binding protein (C/EBP) gene can produce several N-terminally
truncated isoforms. Liver-enriched activator protein (LAP) is a transcriptional
activator in many systems, whereas liver-enriched inhibitory protein (LIP) ... Cited by 21 - Related articles - All 4 versions
- ►shouxi.net L Qiao, PS MacLean, J Schaack, DJ Orlicky, C … - Diabetes, 2005 - Am Diabetes Assoc Adiponectin is an adipose-derived hormone that enhances insulin sensitivity and
plays an important role in regulating energy homeostasis. Here, we demonstrate
that the DNA encoding the first intron of the human adiponectin gene ... Cited by 63 - Related articles - All 5 versions
- ►jbc.org W Cao, QF Collins, TC Becker, J Robidoux, EG … - Journal of Biological Chemistry, 2005 - ASBMB Hepatic gluconeogenesis is essential for maintaining blood glucose levels during
fasting and is the major contributor to postprandial and fasting hyperglycemia
in diabetes. Gluconeogenesis is a classic cAMP/protein kinase A-dependent ... Cited by 39 - Related articles - BL Direct - All 5 versions
- ►nih.gov SS Chen, JF Chen, PF Johnson, V Muppala, … - Molecular and Cellular Biology, 2000 - Am Soc Microbiol Knockout of C/EBP causes a severe loss of liver function and, subsequently,
neonatal lethality in mice. By using a gene replacement approach, we generated a
new C/EBP -null mouse strain in which C/EBP , in addition to its own ... Cited by 65 - Related articles - BL Direct - All 4 versions
- ►shouxi.net J Yang, CM Croniger, J Lekstrom-Himes, P … - Journal of Biological Chemistry, 2005 - ASBMB Although CCAAT/enhancer-binding protein α (C/EBPα) is essential for initiating
or sustaining several metabolic processes during the perinatal period, the
consequences of total ablation of C/EBPα during postnatal development have ... Cited by 32 - Related articles - BL Direct - All 5 versions