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Scholar Results 1 - 10 of about 101 related to Shao: Chronic hyperglycemia enhances PEPCK gene expression and hepatocellular glucose production.... (0.12 sec) 

Chronic hyperglycemia enhances PEPCK gene expression and hepatocellular glucose production …

- diabetesjournals.org
J Shao, L Qiao, RC Janssen, M Pagliassotti, … - Diabetes, 2005 - Am Diabetes Assoc
Acute hyperglycemia normally suppresses hepatic glucose production (HGP) and
gluconeogenic gene expression. Conversely, chronic hyperglycemia is accompanied
by progressive increases in basal HGP and is a major contributor to ...
Cited by 29 - Related articles - All 5 versions

Knocking down liver CCAAT/enhancer-binding protein {alpha} by adenovirus-transduced …

- endojournals.org
L Qiao, PS MacLean, H You, J Schaack, J … - Endocrinology, 2006 - Endocrine Soc
CCAAT/enhancer-binding protein- (C/EBP ) is a member of the basic leucine zipper
transcription factor family and regulates expression of several enzymes in the
liver that control glucose and lipid metabolism. Using ...
Cited by 10 - Related articles - BL Direct - All 3 versions

Metabolism in the era of molecular biology

- jbc.org
RW Hanson - Journal of Biological Chemistry, 2005 - ASBMB
I have spent a lifetime in the area of intermediary metabolism and have seen it
move from the center of biochemistry to the backwater of our science in a very
short period, only to be re-discovered by a new generation of biologists. ...
Cited by 13 - Related articles - All 4 versions

CCAAT/Enhancer-binding Protein {alpha} Mediates Induction of Hepatic …

- jbc.org
L Qiao, OA MacDougald, J Shao - Journal of Biological Chemistry, 2006 - ASBMB
Excessive hepatic gluconeogenesis and glucose production are important
contributors to hyperglycemia in both type 1 and type 2 diabetes. In diabetic
humans and animal models, elevated levels of p38 mitogen-activated protein ...
Cited by 14 - Related articles - All 6 versions

Hepatic CCAAT/enhancer binding protein {alpha} mediates induction of lipogenesis and …

- endojournals.org
K Matsusue, O Gavrilova, G Lambert, HB … - Molecular Endocrinology, 2004 - Endocrine Soc
CCAAT/enhancer binding protein (C/EBP ) is a critical factor in glucose
metabolism in the neonate as revealed by conventional C/EBP -null mice that do
not survive beyond the first day after birth because of severe hypoglycemia ...
Cited by 16 - Related articles - BL Direct - All 3 versions

C/EBP b isoforms LIP and LAP modulate progression of the cell cycle in the regenerating …


T Luedde, M Duderstadt, KL Streetz, F Tacke … - Hepatology, 2004 - interscience.wiley.com
The CCAAT enhancer-binding protein (C/EBP) gene can produce several N-terminally
truncated isoforms. Liver-enriched activator protein (LAP) is a transcriptional
activator in many systems, whereas liver-enriched inhibitory protein (LIP) ...
Cited by 21 - Related articles - All 4 versions

C/EBPα regulates human adiponectin gene transcription through an intronic enhancer

- shouxi.net
L Qiao, PS MacLean, J Schaack, DJ Orlicky, C … - Diabetes, 2005 - Am Diabetes Assoc
Adiponectin is an adipose-derived hormone that enhances insulin sensitivity and
plays an important role in regulating energy homeostasis. Here, we demonstrate
that the DNA encoding the first intron of the human adiponectin gene ...
Cited by 63 - Related articles - All 5 versions

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis

- jbc.org
W Cao, QF Collins, TC Becker, J Robidoux, EG … - Journal of Biological Chemistry, 2005 - ASBMB
Hepatic gluconeogenesis is essential for maintaining blood glucose levels during
fasting and is the major contributor to postprandial and fasting hyperglycemia
in diabetes. Gluconeogenesis is a classic cAMP/protein kinase A-dependent ...
Cited by 39 - Related articles - BL Direct - All 5 versions

C/EBPbeta, when expressed from the C/ebpalpha gene locus, can functionally replace C/ …

- nih.gov
SS Chen, JF Chen, PF Johnson, V Muppala, … - Molecular and Cellular Biology, 2000 - Am Soc Microbiol
Knockout of C/EBP causes a severe loss of liver function and, subsequently,
neonatal lethality in mice. By using a gene replacement approach, we generated a
new C/EBP -null mouse strain in which C/EBP , in addition to its own ...
Cited by 65 - Related articles - BL Direct - All 4 versions

Metabolic response of mice to a postnatal ablation of CCAAT/enhancer-binding protein α

- shouxi.net
J Yang, CM Croniger, J Lekstrom-Himes, P … - Journal of Biological Chemistry, 2005 - ASBMB
Although CCAAT/enhancer-binding protein α (C/EBPα) is essential for initiating
or sustaining several metabolic processes during the perinatal period, the
consequences of total ablation of C/EBPα during postnatal development have ...
Cited by 32 - Related articles - BL Direct - All 5 versions


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