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Scholar Results 1 - 10 of about 101 related to Poulsen: Impact of genetic versus environmental factors on the control of muscle glycogen.... (0.08 sec) 

Impact of genetic versus environmental factors on the control of muscle glycogen …

- diabetesjournals.org
P Poulsen, JFP Wojtaszewski, I Petersen, K … - Diabetes, 2005 - Am Diabetes Assoc
Storage of glucose as glycogen accounts for the largest proportion of muscle glucose metabolism
during insulin infusion in normal and insulin-resistant subjects. Studies in first-degree relatives
have indicated a genetic origin of the defective insulin activation of muscle glycogen ...
Cited by 7 - Related articles - All 5 versions

Partial rescue of in vivo insulin signalling in skeletal muscle by impaired insulin …


K Højlund, JFP Wojtaszewski, J Birk, BF Hansen, H … - Diabetologia, 2006 - Springer
Abstract Aims/hypothesis Recently we reported the coexistence of postprandial hypoglycaemia
and moderate insulin resis- tance in heterozygous carriers of the Arg1174Gln mutation in the
insulin receptor gene (INSR). Controlled studies of in vivo insulin signalling in humans ...
Cited by 5 - Related articles - BL Direct - All 3 versions

The primary defect in glycogen synthase activity is not based on increased …


M Gaster, K Brusgaard, A Handberg, K Højlund, … - … and Biophysical Research …, 2004 - Elsevier
The mechanism responsible for the diminished activation of glycogen synthase (GS) in diabetic
myotubes remains unclear, but may involve increased activity and/or expression of glycogen
synthase kinase-3 (GSK-3). In myotubes established from type 2 diabetic and healthy ...
Cited by 7 - Related articles - All 5 versions

Impaired insulin activation and dephosphorylation of glycogen synthase in skeletal …

- endojournals.org
D Glintborg, K Hojlund, NR Andersen, BF … - Journal of Clinical …, 2008 - Endocrine Soc
Results: Reduced insulin-mediated glucose disposal (P < 0.05) was associated with a lower
insulin-stimulated GS activity in PCOS patients (P < 0.05), compared with controls. This was,
in part, explained by absent insulin-mediated dephosphorylation of GS at the NH 2 ...
Cited by 3 - Related articles - All 3 versions

[CITATION] Exercise test and exercise ECG in the diagnosis and treatment of ischemic heart …


JP Clausen, H Oxhøj, JF Hansen, O Pedersen- … - Ugeskrift for …, 1980 - ncbi.nlm.nih.gov
1: Ugeskr Laeger. 1980 Jun 30;142(27):1743-9. [Exercise test and exercise ECG in the
diagnosis and treatment of ischemic heart disease]. [Article in Danish] Clausen JP, Oxhøj
H, Hansen JF, Pedersen-Bjergaard O, Henningsen P, Uhrenholdt A. ...
Cited by 3 - Related articles

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and …


J Rung, S Cauchi, A Albrechtsen, L Shen, G Rocheleau … - Nature Genetics, 2009 - nature.com
Genome-wide association studies have identified common variants that only partially explain
the genetic risk for type 2 diabetes (T2D). Using genome-wide association data from 1,376 French
individuals, we identified 16,360 SNPs nominally associated with T2D and studied these ...
Cited by 1 - Related articles - All 3 versions

Genetic and metabolic effects on skeletal muscle AMPK in young and older twins


B Mortensen, P Poulsen, L Wegner, KL … - American Journal of …, 2009 - Am Physiological Soc
The protein complex AMP-activated protein kinase (AMPK) is believed to play an important role
in the regulation of skeletal muscle glucose and lipid metabolism. Defects in the AMPK system
might therefore be an important factor in the pathogenesis of type 2 diabetes. We aimed ...
Related articles - All 3 versions

Dysregulation of Glycogen Synthase COOH-and NH2-Terminal Phosphorylation by …


K Hojlund, JB Birk, DK Klein, K Levin, AJ Rose, … - Journal of Clinical …, 2009 - Endocrine Soc
Copenhagen Muscle Research Centre (JBB, DKK, AJR, JNN, JFPW), Molecular Physiology
Group, Section of Human Physiology, Department of Exercise and Sport Sciences, University
of Copenhagen, DK-2100 Copenhagen, Denmark; Diabetes Research Centre (KH, KL, ...
Related articles - All 2 versions

Dual Regulation of Muscle Glycogen Synthase during Exercise by Activation and …


C Prats, JW Helge, P Nordby, K Qvortrup, T Ploug, … - Journal of Biological …, 2009 - ASBMB
Glycogen synthase (GS) is considered the rate-limiting enzyme in glycogenesis but still today
there is a lack of understanding on its regulation. We have previously shown
phosphorylation-dependent GS intracellular redistribution at the start of glycogen re- ...
Cited by 1 - Related articles - All 3 versions

Skeletal muscle insulin signaling defects downstream of phosphatidylinositol 3- …


SB Haugaard, O Andersen, S Madsbad, C Frøsig, J … - Diabetes, 2005 - Am Diabetes Assoc
More than 40% of HIV-infected patients on highly active antiretroviral therapy (HAART) experience
fat redistribution (lipodystrophy), a syndrome associated with insulin resistance primarily affecting
insulin-stimulated nonoxidative glucose metabolism (NOGM ins ). Skeletal muscle ...
Cited by 11 - Related articles - BL Direct - All 5 versions


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