M Foretz, N Ancellin, F Andreelli, Y Saintillan … - Diabetes, 2005 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) is a major therapeutic target for the
treatment of diabetes. We investigated the effect of a short-term overexpression
of AMPK specifically in the liver by adenovirus-mediated transfer of a gene ... Cited by 102 - Related articles - All 5 versions
- ►endojournals.org F Andreelli, M Foretz, C Knauf, PD Cani, C … - Endocrinology, 2006 - Endocrine Soc The AMP-activated kinase (AMPK) is a serine threonine kinase that functions as a
fuel sensor to regulate energy balance at both cellular and whole-body levels.
Here we studied how hepatic AMPK 2 isoform affects hepatic glucose ... Cited by 62 - Related articles - All 3 versions
- ►diabetesjournals.org R Bergeron, SF Previs, GW Cline, P Perret, … - Diabetes, 2001 - Am Diabetes Assoc Activation of AMP-activated protein kinase (AMPK) with
5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) increases glucose
transport in skeletal muscle via an insulin-independent pathway. To examine ... Cited by 134 - Related articles - BL Direct - All 4 versions
- ►nih.gov B Viollet, F Andreelli, SB Jørgensen, C … - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig AMP-activated protein kinase (AMPK) is viewed as a fuel sensor for glucose and
lipid metabolism. To better understand the physiological role of AMPK, we
generated a knockout mouse model in which the AMPKα2 catalytic subunit ... Cited by 207 - Related articles - BL Direct - All 11 versions
B Cool, B Zinker, W Chiou, L Kifle, N Cao, M … - Cell metabolism, 2006 - Elsevier AMP-activated protein kinase (AMPK) is a key sensor and regulator of
intracellular and whole-body energy metabolism. We have identified a
thienopyridone family of AMPK activators. A-769662 directly stimulated ... Cited by 91 - Related articles - All 9 versions
AK Saha, PR Avilucea, JM Ye, MM Assifi, … - Biochemical and Biophysical Research …, 2004 - Elsevier Thiazolidinediones have been shown to activate AMP-activated protein kinase
activity in cultured cells. Whether they have a similar effect in vivo and if so
whether it is physiologically relevant is not known. To assess these ... Cited by 102 - Related articles - All 4 versions
B Viollet, M Foretz, B Guigas, S Horman, R … - The Journal of physiology, 2006 - Physiological Soc It is now becoming evident that the liver has an important role in the control
of whole body metabolism of energy nutrients. In this review, we focus on recent
findings showing that AMP-activated protein kinase (AMPK) plays a major ... Cited by 80 - Related articles - BL Direct - All 9 versions
- ►physiology.org MM Assifi, G Suchankova, S Constant, M … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Acute increases in the concentration of malonyl-CoA play a pivotal role in
mediating the decrease in fatty acid oxidation that occurs in many tissues
during refeeding after a fast. In this study, we assess whether such ... Cited by 27 - Related articles - BL Direct - All 4 versions
SB Jørgensen, B Viollet, F Andreelli, C … - Journal of Biological Chemistry, 2004 - ASBMB We investigated the importance of the two catalytic α-isoforms of the
5′-AMP-activated protein kinase (AMPK) in 5-aminoimidazole-4-carboxamide-1-β-
4-ribofuranoside (AICAR) and contraction-induced glucose uptake in skeletal ... Cited by 190 - Related articles - BL Direct - All 4 versions
- ►jbc.org T Kawaguchi, K Osatomi, H Yamashita, T … - Journal of Biological Chemistry, 2002 - ASBMB Carbohydrate-responsive element-binding protein (ChREBP) is a new transcription
factor that binds to the carbohydrate-responsive element of the L-type pyruvate
kinase gene (L-PK). The aim of this study was to investigate the mechanism ... Cited by 139 - Related articles - BL Direct - All 5 versions
