- ►shouxi.net I Bogacka, H Xie, GA Bray, SR Smith - Diabetes, 2005 - Am Diabetes Assoc Thiazolidenediones such as pioglitazone improve insulin sensitivity in diabetic
patients by several mechanisms, including increased uptake and metabolism of
free fatty acids in adipose tissue. The purpose of the present study was to ... Cited by 120 - Related articles - All 5 versions
- ►nih.gov L Wilson-Fritch, S Nicoloro, M Chouinard, MA … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig Adipose tissue plays a central role in the control of energy homeostasis through
the storage and turnover of triglycerides and through the secretion of factors
that affect satiety and fuel utilization. Agents that enhance insulin ... Cited by 152 - Related articles - BL Direct - All 15 versions
- ►endojournals.org I Bogacka, B Ukropcova, M McNeil, JM Gimble … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc Results: The treatment of adipocytes with forskolin increased mitochondrial copy
number and the expression of genes involved in mitochondrial biogenesis (PPAR
coactivator 1 and transcriptional factor A) and fatty acid oxidation (PPAR ... Cited by 50 - Related articles - BL Direct - All 5 versions
- ►nih.gov L Wilson-Fritch, A Burkart, G Bell, K … - Molecular and Cellular Biology, 2003 - Am Soc Microbiol White adipose tissue is an important endocrine organ involved in the control of
whole-body metabolism, insulin sensitivity, and food intake. To better
understand these functions, 3T3-L1 cell differentiation was studied by ... Cited by 135 - Related articles - BL Direct - All 8 versions
RK Semple, VC Crowley, CP Sewter, M Laudes, … - International Journal of Obesity, 2003 - nature.com Peroxisome proliferator-activated receptor gamma coactivator 1 (PGC1 ) is an
accessory protein which can potentiate the transcriptional activation function
of many nuclear hormone receptors. Its tissue distribution and ... Cited by 56 - Related articles - BL Direct - All 3 versions
- ►endojournals.org E Hondares, O Mora, P Yubero, MR de la … - Endocrinology, 2006 - Endocrine Soc Thiazolidinediones (TZDs) are insulin-sensitizing drugs currently used to treat
type 2 diabetes. They are activators of peroxisome proliferator-activated
receptor (PPAR)- , and adipose tissue constitutes a major site for their ... Cited by 42 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org JX Rong, Y Qiu, MK Hansen, L Zhu, V Zhang, … - Diabetes, 2007 - Am Diabetes Assoc The objective of this study was to further establish and confirm the
relationship of adipose mitochondrial biogenesis in diabetes/obesity and the
effects of rosiglitazone (RSG), a peroxisome proliferator–activated ... Cited by 19 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org G Boden, C Homko, M Mozzoli, LC Showe, C … - Diabetes, 2005 - Am Diabetes Assoc Thiazolidinediones (TZDs) are a new class of insulin-sensitizing drugs. To
explore how and in which tissues they improve insulin action, we obtained fat
and muscle biopsies from eight patients with type 2 diabetes before and 2 ... Cited by 53 - Related articles - All 5 versions
MF McCarty - Medical hypotheses, 2005 - Elsevier Excessive accumulation of triglycerides and certain fatty acid derivatives in
skeletal muscle and other tissues appears to mediate many of the adverse effects
of insulin resistance syndrome. Although fatty diets and obesity can ... Cited by 18 - Related articles - All 19 versions
