- ►diabetesjournals.org LD Mastrandrea, SM Sessanna, SG Laychock - Diabetes, 2005 - Am Diabetes Assoc Sphingosine-1 phosphate (S1P) is a bioactive sphingolipid with the potential to
mobilize Ca 2+ , to inhibit apoptosis, and to promote mitogenesis. Sphingosine
kinase (SPHK) and S1P were characterized in INS-1 insulinoma cells and ... Cited by 21 - Related articles - All 5 versions
SG Laychock, Y Tian, SM Sessanna - Diabetes, 2003 - Am Diabetes Assoc The endothelial differentiation gene (EDG) receptors are a class of G
protein-coupled receptors. EDG-1, -3, -5, -6, and -8 bind the bioactive lipid
sphingosine-1-phosphate (SPP) as the primary signaling ligand. EDG-2, -4, ... Cited by 11 - Related articles - BL Direct - All 4 versions
- ►endojournals.org SG Laychock, SM Sessanna, MH Lin, LD … - Endocrinology, 2006 - Endocrine Soc Cytokines mediate pancreatic islet ß-cell apoptosis and necrosis, leading to
loss of insulin secretory capacity and type 1 diabetes mellitus. The cytokines,
IL-1ß and interferon- , induced terminal deoxynucleotidyl ... Cited by 14 - Related articles - BL Direct - All 4 versions
ZHU Qun, JIN Jun-fei, S Xiao-hong, LIU Cui- … - Acta Pharmacologica Sinica, 2008 - chinaphar.com Ceramidase (CDase) deacylates Cer to form SPH, which can be further
phosphorylated to S1P by the sphingosine kinase (SPHK). Thus far, 3 subtypes of
CDase, namely, acid, neutral, and alkaline CDase, have been cloned and ... Cited by 3 - Related articles - Cached - BL Direct - All 8 versions
MH Kim, JS Park, HJ Chang, MK Baek, HR … - Journal of cellular biochemistry, 2008 - interscience.wiley.com There is a strong correlation between the overexpression of urokinase-type
plasminogen activator receptor (uPAR) and gastric cancer invasion. This study
examined the effect of phospholipid lysophosphatidic acid (LPA) on uPAR ... Cited by 4 - Related articles - BL Direct - All 4 versions
K Geoffroy, N Wiernsperger, M Lagarde, S El … - Journal of Biological Chemistry, 2004 - ASBMB Advanced glycation end-products (AGE) are generated by chronic hyperglycaemia
and may cause diabetic microvascular complications such as diabetic nephropathy.
Many factors influence the development of diabetic nephropathy; however, ... Cited by 17 - Related articles - BL Direct - All 4 versions
[CITATION] Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell …
A Billich, F Bornancin, D Mechtcheriakova, F … - Cellular Signalling, 2005 - Oxford; New York: Pergamon Press, 1988- Cited by 5 - Related articles
R Kacimi, DA Vessey, N Honbo, JS Karliner - Journal of molecular and cellular cardiology, 2007 - Elsevier Cardiac fibroblasts are critical for the maintenance of extracellular matrix
deposition and turnover in the normal heart and are key mediators of
inflammatory and fibrotic myocardial remodeling in the injured and failing ... Cited by 5 - Related articles - All 8 versions
MM Ma, JL Chen, GG Wang, H Wang, Y Lu, JF … - Diabetologia, 2007 - Springer Page 1. ARTICLE Sphingosine kinase 1 participates in insulin signalling and regulates
glucose metabolism and homeostasis in KK/Ay diabetic mice ... Cited by 6 - Related articles - BL Direct - All 4 versions
CB Xu, J Hansen-Schwartz, L Edvinsson - Acta pharmacologica Sinica, 2004 - ncbi.nlm.nih.gov Sphingosine-1-phosphate (S1P) has diverse biological functions acting inside
cells as a second messenger to regulate cell proliferation and survival, and
extracellularly, as a ligand for a group of G protein-coupled receptors ... Cited by 22 - Related articles - BL Direct - All 2 versions
