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Scholar Results 1 - 10 of about 101 related to Sima: The effect of C-peptide on cognitive dysfunction and hippocampal apoptosis in type.... (0.12 sec) 

The effect of C-peptide on cognitive dysfunction and hippocampal apoptosis in type 1 …

- shouxi.net
AAF Sima, Z Li - Diabetes, 2005 - Am Diabetes Assoc
Primary diabetic encephalopathy is a recently recognized late complication of
diabetes resulting in a progressive decline in cognitive faculties. In the
spontaneously type 1 diabetic BB/Wor rat, we recently demonstrated that ...
Cited by 34 - Related articles - All 6 versions

The role of impaired insulin/IGF action in primary diabetic encephalopathy


Z Li, W Zhang, AAF Sima - Brain research, 2005 - Elsevier
We have previously shown that hippocampal neuronal apoptosis accompanied by
impaired cognitive functions occurs in type 1 diabetic BB/Wor rats. To
differentiate the contribution by insulin deficiency vs. that by ...
Cited by 31 - Related articles - All 4 versions

Insulin, C-peptide, hyperglycemia, and central nervous system complications in diabetes


AAF Sima, H Kamiya, Z Guo Li - European journal of pharmacology, 2004 - Elsevier
Diabetes is an increasingly common disorder which causes and contributes to a
variety of central nervous system (CNS) complications which are often associated
with cognitive deficits. There appear to be two types of diabetic ...
Cited by 47 - Related articles - All 3 versions

Hippocampal neuronal apoptosis in type 1 diabetes


ZG Li, W Zhang, G Grunberger, AAF Sima - Brain research, 2002 - Elsevier
Duration-related cognitive impairment is an increasingly recognized complication
of type 1 diabetes. To explore potential underlying mechanisms, we examined
hippocampal abnormalities in the spontaneously type 1 diabetic BB/W rat. As ...
Cited by 102 - Related articles - All 4 versions

Molecular alterations underlie nodal and paranodal degeneration in type 1 diabetic …


AAF Sima, W Zhang, ZG Li, Y Murakawa, CR … - Diabetes, 2004 - Am Diabetes Assoc
To explore the molecular abnormalities underlying the degeneration of the node
of Ranvier, a characteristic aberration of type 1 diabetic neuropathy, we
examined in type 1 BB/Wor and type 2 BBZDR/Wor rats changes in expression ...
Cited by 40 - Related articles - BL Direct - All 4 versions

C-peptide enhances insulin-mediated cell growth and protection against high glucose- …


Z Li, W Zhang, A Sima - Diabetes/Metabolism Reviews - interscience.wiley.com
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Cited by 67 - Related articles - BL Direct - All 4 versions

C-peptide and central nervous system complications in diabetes


Z Li, AAF Sima - Experimental Diabesity Research, 2004 - pubmedcentral.nih.gov
Substantial evidence collected from clinical data and experimental studies has
indicated that CNS is not spared from diabetes complications. Impairments in CNS
function are well documented in both type 1 and type 2 diabetic patients as ...
Cited by 16 - Related articles - All 4 versions

C-peptide prevents nociceptive sensory neuropathy in type 1 diabetes


H Kamiya, W Zhang, AAF Sima - Annals of neurology, 2004 - interscience.wiley.com
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Cited by 33 - Related articles - BL Direct - All 3 versions

[CITATION] The BB/ZDR-rat; A model for type II diabetic neuropathy


AAF Sima, AC Merry, DE Hall, M Grant, FT … - Exp Clin Endocrinol Diabetes, 1997
Cited by 15 - Related articles

Alzheimer-like changes in rat models of spontaneous diabetes

- diabetesjournals.org
Z Li, W Zhang, AAF Sima - Diabetes, 2007 - Am Diabetes Assoc
RESULTS—Neuronal loss occurred in both models, significantly more so in type 2
diabetic BBZDR/Wor rats compared with type 1 diabetic BB/Wor rats and was
associated with a ninefold increase of dystrophic neurites. APP, ...
Cited by 27 - Related articles - BL Direct - All 5 versions


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