- ►diabetesjournals.org DP Pomerleau, RJ Bagley, DV Serreze, CE … - Diabetes, 2005 - Am Diabetes Assoc The diabetogenic major histocompatibility complex (MHC) (H2 g7 ) of NOD mice
comprises contributions from several class II loci collectively designated as
Idd1. Introduction of the H2 gx haplotype from the related but diabetes- ... Related articles - All 3 versions
N Babaya, H Ikegami, Y Kawaguchi, T … - INTERNATIONAL JOURNAL OF DIABETES, 2000 - ijod.uaeu.ac.ae By using a congenic non-obese diabetic (NOD) mouse strain that possesses a
recombinant major histocompatibility complex (MHC) from a diabetes-resistant
sister strain, the CTS mouse, we have previously mapped a second component ... Cited by 8 - Related articles - View as HTML - BL Direct - All 2 versions
K Inoue, H Ikegami, T Fujisawa, S Noso, K … - Diabetologia, 2004 - Springer Aims/hypothesis. Recent studies have revealed that MHC-linked susceptibility to
Type 1 diabetes is deter- mined by multiple components. In the non-obese dia-
betic (NOD) mouse, a second component (Idd16) has been mapped to a region ... Cited by 10 - Related articles - BL Direct - All 4 versions
N Babaya, H Ikegami, T Fujisawa, H Ueda, K … - Autoimmunity, 2002 - informahealthcare.com Autoimmune type 1 diabetes is caused by specific destruction of the pancreatic b
cells. Although the precise mechanism of b cell destruction is still under
investi- gation, it is known that autoimmunity plays a major role in the ... Cited by 10 - Related articles - BL Direct - All 7 versions
[CITATION] Individual NOD mice exhibit unique patterns of CD8 T cell reactivity to three islet antigens, …
- ►jimmunol.org T Takaki, SM Lieberman, TM Holl, B Han, P … - The Journal of Immunology, 2004 - Am Assoc Immnol The NOD mouse is a model for autoimmune type 1 diabetes in humans. CD8 + T cells
are essential for the destruction of the insulin-producing pancreatic cells
characterizing this disease. AI4 is a pathogenic CD8 + T cell clone, ... Cited by 11 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org N Deruytter, O Boulard, HJ Garchon - Diabetes, 2004 - Am Diabetes Assoc Major histocompatibility complex (MHC) plays a largely predominant role in the
genetic predisposition to type 1 diabetes, in both humans and rodents. While
class II loci have long been recognized as essential, they do not fully ... Cited by 16 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] CE Mathews, RT Graser, DV Serreze, EH … - Diabetes, 2000 - Am Diabetes Assoc MHC class II region identity with the H 2 g 7 haplotype of NOD mice. However,
CTS mice were reported to express distinct but undefined MHC class I gene prod-
ucts. Because diabetes frequency was reduced 56% in females of a NOD stock ... Cited by 19 - Related articles - BL Direct - All 3 versions
RT Graser, CE Mathews, EH Leiter, DV … - Immunogenetics, 1999 - Springer RT Graser 7 CE Mathews 7 EH Leiter 7 DV Serreze (Y) The Jackson Laboratory, 600
Main St., Bar Harbor, ME 04609, USA e-mail: dvs6aretha.jax.org, Tel.:
c1-207-2886403, Fax: c1-207-2886079 The first two authors contributed ... Cited by 17 - Related articles - BL Direct - All 3 versions
