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Scholar Results 1 - 10 of about 101 related to Wolf: From the periphery of the glomerular capillary wall toward the center of disease. (0.09 sec) 

From the periphery of the glomerular capillary wall toward the center of disease

- diabetesjournals.org
G Wolf, S Chen, FN Ziyadeh - Diabetes, 2005 - Am Diabetes Assoc
Nephropathy is a major complication of diabetes. Alterations of mesangial cells
have traditionally been the focus of research in deciphering molecular
mechanisms of diabetic nephropathy. Injury of podocytes, if recognized at ...
Cited by 188 - Related articles - All 9 versions

Perspectives in Diabetes


G Wolf, S Chen, FN Ziyadeh - AGE, 2005 - Am Diabetes Assoc
Nephropathy is a major complication of diabetes. Alter- ations of mesangial
cells have traditionally been the focus of research in deciphering molecular
mechanisms of diabetic nephropathy. Injury of podocytes, if recog- nized at ...
Related articles

Nephrin expression is reduced in human diabetic nephropathy

- diabetesjournals.org
S Doublier, G Salvidio, E Lupia, V … - Diabetes, 2003 - Am Diabetes Assoc
We studied the distribution of nephrin in renal biopsies from 17 patients with
diabetes and nephrotic syndrome (7 type 1 and 10 type 2 diabetes), 6 patients
with diabetes and microalbuminuria (1 type 1 and 5 type 2 diabetes), and 10 ...
Cited by 163 - Related articles - BL Direct - All 6 versions

Selective impairment of gene expression and assembly of nephrin in human diabetic …


A Benigni, E Gagliardini, S Tomasoni, M … - Kidney international, 2004 - nature.com
Recent disclosure of podocyte proteins has unraveled previously rather
mysterious mechanisms that govern glomerular perm-selectivity in health and
disease. Here we addressed the role of nephrin, CD2-associated protein ...
Cited by 79 - Related articles - BL Direct - All 4 versions

Glomerular cell number in normal subjects and in type 1 diabetic patients


MW Steffes, D Schmidt, R Mccrery, JM … - Kidney international, 2001 - nature.com
1 The International Diabetic Nephropathy Study Group (institution) members
include: (1) Keith Drummond (principal investigator), Christine Aebi, Mimi
Belmonte, Robert Gardiner, Paul Goodyear, Michael Kramer, Constantin ...
Cited by 142 - Related articles - BL Direct - All 4 versions

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte …

- diabetesjournals.org
K Susztak, AC Raff, M Schiffer, EP Böttinger - Diabetes, 2006 - Am Diabetes Assoc
Diabetic nephropathy is the most common cause of end-stage renal disease in the
US Recent studies demonstrate that loss of podocytes is an early feature of
diabetic nephropathy that predicts its progressive course. Cause and ...
Cited by 165 - Related articles - BL Direct - All 7 versions

Podocyte loss and progressive glomerular injury in type II diabetes.

- nih.gov [PDF] 
ME Pagtalunan, PL Miller, S Jumping-Eagle, … - Journal of Clinical Investigation, 1997 - Am Soc Clin Investig
Kidney biopsies from Pima Indians with type II diabetes were analyzed. Subjects
were classified clinically as having early diabetes (n = 10), microalbuminuria
(n = 17), normoalbuminuria, despite a duration of diabetes equal to that of ...
Cited by 358 - Related articles - BL Direct - All 8 versions

Is Podocyte Injury Relevant in Diabetic Nephropathy?

- diabetesjournals.org
M Dalla Vestra, A Masiero, AM Roiter, A Saller … - Diabetes, 2003 - Am Diabetes Assoc
Podocyte structural changes have been suggested to be involved in the
pathogenesis of albuminuria in diabetes. We evaluated podocytes density, number,
and structure in 67 white patients with type 2 diabetes: 21 ...
Cited by 125 - Related articles - BL Direct - All 4 versions

Effects of high glucose and TGF-&bgr; 1 on the expression of collagen IV and vascular …


MC Iglesias-de la Cruz, FN Ziyadeh, M Isono … - Kidney international, 2002 - nature.com
The podocyte takes center stage in the pathogenesis of glomerular basement
membrane (GBM) thickening and proteinuria in diabetic glomerulopathy. In part,
GBM thickening may occur when the podocyte synthesizes increased amounts of ...
Cited by 121 - Related articles - BL Direct - All 7 versions

Angiotensin II stimulates {alpha} 3 (IV) collagen production in mouse podocytes via TGF-{ …

- oxfordjournals.org
S Chen, JS Lee, MC Iglesias-De La Cruz, A … - Nephrology Dialysis Transplantation, 2005 - ERA-EDTA
Results. AngII 10 –10 M was found to stimulate the production of 3(IV)
collagen significantly in as short a time as 3 h. The expression of 3(IV)
collagen was influenced by the TGF-ß system, but AngII did not increase ...
Cited by 43 - Related articles - All 5 versions


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